Intranasal Corticosteroid Theraphy in Idiopathic Rhinitis: a Comparative Study with Allergic Rhinitis

American-Academy-of-Allergy-Asthma-and-Immunology Annual Meeting -- MAR 18-22, 2011 -- San Francisco, CAWOS: 000295846400777…Amer Acad Allergy Asthma & Immuno

Efficacy and safety of once daily triamcinolone acetonide aqueous nasal spray in adults with non-allergic and allergic rhinitis

WOS: 000328809500005PubMed: 23031657Background: The efficacy of corticosteroid has not been thoroughly studied in the treatment of non-allergic rhinitis. This study was designed to compare the efficacy of nasal corticosteroid in patients with allergic rhinitis (AR), and non-allergic rhinitis (NAR). Methods: The efficacy of triamcinolone acetonide nasal spray (TANS) on total nasal symptom scores (TNSS), and nasal peak inspiratory flow rate (nPIFR) was studied in a six-week parallel-group trial of NAR (n: 25), and AR (n: 16) patients. Health-related quality of life (HRQoL) and Epworth Sleepiness Scale (ESS) were also analysed. Results: The TNSSs, and symptom scores of conjunctivitis, snoring, and postnasal drainage were significantly improved in both groups, after two and six weeks of treatment. In contrast to AR, patients with NAR had statistically significant improvement in nasal obstruction, and postnasal drainage beginning from two weeks of the treatment. nPIFR slightly increased in both groups. Scores of generic (SF-36), rhinitis specific (MiniRQLQ) and ESS questionnaires generally improved better in AR than MAR. TANS was well-tolerated in AR and NAR groups with minor adverse events including headache, nasal burning, and bitter mouth taste. Conclusions: Our study disproved the idea of ineffectiveness of corticosteroid treatment in NAR, and showed that triamcinolone acetate may be an alternative drug in the treatment of NAR. (C) 2012 SEICAP Published by Elsevier Espana, S.L. All rights reserved.Kirikkale University Projects of Scientific ResearchesKirikkale University [2007/4]This work was supported by a grant from Kirikkale University Projects of Scientific Researches (grant no: 2007/4) which was received by Baccioglu Kavut, and Kalpaklioglu

Comparement of Azelastin versus Triamcinolone Nasal Spray in Allergic and Nonallergic Rhinitis

65th Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology -- MAR 13-17, 2009 -- Washington, DCWOS: 000263596300520…Amer Acad Allergy, Asthma & Immuno

Does Nasal Provocation Test Affect Quality Of Life In Idiopathic Rhinitis Compared To Allergics?

66th Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology -- FEB 26-MAR 02, 2010 -- New Orleans, LAWOS: 000280204100662…Amer Acad Allergy, Asthma & Immuno

Allergic and Nonallergic Rhinitis: Can We Find the Differences/Similarities between the Two Pictures?

WOS: 000267195300010PubMed: 19544169The diagnostic challenge of rhinitis is to determine the etiology, specifically whether it is allergic or nonallergic. We therefore evaluated the general features of patients with allergic (AR) and nonallergic rhinitis (NAR), as well as health-related quality of life (HRQoL). The study group consisted of 323 patients (201 F/122 M) with a mean age of 31.79 +/- 12.64 years. Almost two thirds of the population had AR (63.5%). Neither the demographic characteristics nor the duration of rhinitis was different between the two groups. Total immunoglobulin E was significantly higher in AR. Although both groups displayed a mild-intermittent rhinitis profile, patients with AR had more seasonal and NAR had more perennial symptoms (p = 0.01). Frequency of nasal obstruction was comparable in both groups, whereas patients with AR significantly complained of rhinorrhea (86.8%), followed by nasal obstruction, sneezing, and nasal itching compared with the NAR group. Conjunctivitis and sinusitis were more prominent in the AR than NAR group (p = 0.01). However, the prevalences of asthma and bronchial hyperreactivity were not different, as well as the other allergic or systemic comorbidities. Furthermore, the impairment in HRQoL was similar in both groups, using a generic questionnaire- Short form-36 (SF-36). In conclusion, although the allergy test results still remain the only relevant difference, the diagnosis of NAR is important as it has many differences/similarities with AR and is seen almost half as often as AR in patients with chronic rhinitis

Which is the current hypothesis for idiopathic rhinitis; allergic or neurogenic?

29th Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI) -- JUN 05-09, 2010 -- London, ENGLANDWOS: 000329462100360…European Acad Allergy and Clin Immuno

Predicting the outcome of a non-steroidal anti-inflammatory drug provocation test-do we really need it?

30th Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI) -- JUN 11-15, 2011 -- Istanbul, TURKEYKalpaklioglu, A. Fusun/0000-0002-6548-6932WOS: 000329462200360…European Acad Allergy & Clin Immunol (EAACI

Comparison of nasal nitric oxide in allergic versus nonallergic rhinitis

World Allergy and Asthma Congress of the European-Academy-of-Allergy-and-Clinical-Immunology and World-Allergy-Organization -- JUN 22-26, 2013 -- Milan, ITALYWOS: 000325142901177…European Acad Allergy & Clin Immunol, World Allergy Or

Medication adherence, personality traits and health-related quality of life in rhinitis patients

29th Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI) -- JUN 05-09, 2010 -- London, ENGLANDKalpaklioglu, A. Fusun/0000-0002-6548-6932WOS: 000329462103271…European Acad Allergy and Clin Immuno

Allergic Rhinitis: Can We Identify Nonadherence to Therapy and Its Predictors Easily in Daily Practice?

WOS: 000323873700004PubMed: 24260976Background: Allergic rhinitis (AR) is a common chronic condition with significant consequences if left untreated (eg, poor health outcomes, disease progression, and increased health care costs). However, about half of all patients do not fill their prescription. The factors associated with adherence are complex, and many remain poorly defined and understood. Objectives: This pilot study had 2 objectives. First, to determine whether the medication adherence report scale (MARS) can be applied to identify adherence/nonadherence in patients with AR using patients with chronic obstructive pulmonary disease (COPD) as controls. Second, to identify AR profiles that indicate a particularly high risk of nonadherence. Methods: AR patients completed the Eysenck Personality Questionnaire-Revised Abbreviated-Form (EPQR-A), the Short Form 36 Health Survey (SF-36), the Mini Rhinitis Quality of Life Questionnaire (Mini-RQLQ), and the MARS. Symptom severity was assessed before and after treatment. Results: The study population comprised 85 AR patients and 50 COPD patients. Females had worse adherence (significant only in total and unintentional scores) and higher extraversion scores. None of the personality traits predicted adherence. Neuroticism was negatively correlated with the SF-36 score (P<.001). A low to moderate correlation was observed between posttreatment improvement in specific/generic health-related quality of life and MARS scores in AR patients (P=.002, r=0.332; and P=.022, r=-0.251; respectively). Higher educational level was found to significantly increase adherence (P=.01, r=0.223). Conclusions: Our study did not reveal a personality effect. However, it did suggest that use of a brief, self-completed medication adherence questionnaire in daily practice can enable health professionals to identify suboptimal adherence in patients who would benefit from close follow-up