Platelet-rich fibrin (PRF) as an autologous biomaterial after an endodontic surgery: Case reports

The successful treatment of periapical inflammatory lesion depends on the reduction and elimination of the offending organism. Periapical surgery, one of the treatment alternatives, includes the curettage of all periapical soft tissues and sometimes application of different biomaterials to enhance the new bone formation in the defect site. The cases reported here present the management of the periapical inflammatory lesion using platelet-rich fibrin (PRF) which acts as a source of growth factors at the healing site. PRF features all the necessary parameters permitting optimal healing, but numerous perspectives of PRF have still to be clinically tested