129 research outputs found
Patterns of Retinal Damage Facilitate Differential Diagnosis between Susac Syndrome and MS
Susac syndrome, a rare but probably underdiagnosed combination of encephalopathy, hearing loss, and visual deficits due to branch retinal artery occlusion of unknown aetiology has to be considered as differential diagnosis in various conditions. Particularly, differentiation from multiple sclerosis is often challenging since both clinical presentation and diagnostic findings may overlap. Optical coherence tomography is a powerful and easy to perform diagnostic tool to analyse the morphological integrity of retinal structures and is increasingly established to depict characteristic patterns of retinal pathology in multiple sclerosis. Against this background we hypothesised that differential patterns of retinal pathology facilitate a reliable differentiation between Susac syndrome and multiple sclerosis. In this multicenter cross-sectional observational study optical coherence tomography was performed in nine patients with a definite diagnosis of Susac syndrome. Data were compared with age-, sex-, and disease duration-matched relapsing remitting multiple sclerosis patients with and without a history of optic neuritis, and with healthy controls. Using generalised estimating equation models, Susac patients showed a significant reduction in either or both retinal nerve fibre layer thickness and total macular volume in comparison to both healthy controls and relapsing remitting multiple sclerosis patients. However, in contrast to the multiple sclerosis patients this reduction was not distributed over the entire scanning area but showed a distinct sectorial loss especially in the macular measurements. We therefore conclude that patients with Susac syndrome show distinct abnormalities in optical coherence tomography in comparison to multiple sclerosis patients. These findings recommend optical coherence tomography as a promising tool for differentiating Susac syndrome from MS
Fructo-oligosaccharides and glucose homeostasis: a systematic review and meta-analysis in animal models
Testing CPT- and Lorentz-odd electrodynamics with waveguides
We study CPT- and Lorentz-odd electrodynamics described by the Standard Model
Extension. Its radiation is confined to the geometry of hollow conductor
waveguide, open along . In a special class of reference frames, with
vanishing both 0-th and components of the background field, , we realize a number of {\em huge and macroscopically detectable}
effects on the confined waves spectra, compared to standard results.
Particularly, if points along (or ) direction only
transverse electric modes, with , should be observed propagating
throughout the guide, while all the transverse magnetic, , are absent.
Such a strong mode suppression makes waveguides quite suitable to probe these
symmetry violations using a simple and easily reproducible apparatus.Comment: 11pages, double-spacing, tex forma
Considering Soil Potassium Pools with Dissimilar Plant Availability
Soil potassium (K) has traditionally been portrayed as residing in four functional pools: solution K, exchangeable K, interlayer (sometimes referred to as “fixed” or “nonexchangeable”) K, and structural K in primary minerals. However, this four-pool model and associated terminology have created confusion in understanding the dynamics of K supply to plants and the fate of K returned to the soil in fertilizers, residues, or waste products. This chapter presents an alternative framework to depict soil K pools. The framework distinguishes between micas and feldspars as K-bearing primary minerals, based on the presence of K in interlayer positions or three-dimensional framework structures, respectively; identifies a pool of K in neoformed secondary minerals that can include fertilizer reaction products; and replaces the “exchangeable” K pool with a pool defined as “surface-adsorbed” K, identifying where the K is located and the mechanism by which it is held rather than identification based on particular soil testing procedures. In this chapter, we discuss these K pools and their behavior in relation to plant K acquisition and soil K dynamics
Short hairpin RNA- mediated gene knockdown of FOXM1 inhibits the proliferation and metastasis of human colon cancer cells through reversal of epithelial-to-mesenchymal transformation
Central role of Snail1 in the regulation of EMT and resistance in cancer: a target for therapeutic intervention
Wochenbettverlauf nach drohender FrĂĽhgeburt - Auswirkungen eines Infektions-Screenings in der Schwangerschaft
Wochenbettverlauf nach drohender FrĂĽhgeburt - Auswirkungen eines Infektions-Screenings in der Schwangerschaft
Ăśber den Entwurf eines hochratigen digitalen Ăśbertragungssystems mit Hilfe der Pol-Nullstellen-Verteilung
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