14 research outputs found
Figure S5 from EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth
Figure S5: PPARγ Antagonist GW9662 modulates induces tumor regression and modulates the TME.</p
Figure S2 from EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth
Figure S2: Innate immune cells are regulated by GM-CSF and contributes to tumorigenesis.</p
Table S1 from EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth
Table S1: BALF Patient Sample Clinical Features</p
Figure S1 from EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth
Figure S1: Myeloid cell regulation during lung tumorigenesis.</p
Figure S8 from EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth
Figure S8: AMs transfer nutrients to tumor cells.</p
Figure S4 from EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth
Figure S4: Deficiency of PPARγ in CSF1R- or CD11c-expressing cells suppresses tumor growth. </p
Figure S7 from EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth
Figure S7: PPARγ antagonist GW9662 rewires Alveolar macrophage metabolism within the TME.</p
Figure S6 from EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth
Figure S6: Single cell analysis of tumorigenesis in humans reveals rewired LUAD patient macrophage lipid and mitochondrial metabolism.</p
Figure S9 from EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth
Figure S9: Statins inhibit EGFRmutant tumor cell growth and oncogenic signaling.</p
Figure S3 from EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth
Figure S3. Lipid import from myeloid cells in the TME.</p