712 research outputs found

    Prosecution and Peace: A Role for Amnesty before the ICC

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    Enforcing access to information and privacy rights: evaluating proposals for an information protection regulator for SA

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    Note on current developments, the necessity for a proposed statutory regime for the protection of privacy rights

    Upper Columbia United Tribes Fisheries Center Fisheries Technical Report No. 12

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    Predicting the Effect of Reduced Streamflow on Rainbow Trout, Brown Trout, and Sculpin Populations in Chamokane Creek Using the Instream Flow Incremental Methodology (IFIM

    Feasibility of a randomized controlled trial of functional strength training for people between six months and five years after stroke: FeSTivaLS trial

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    Background: Functional Strength Training (FST) could enhance recovery late after stroke. The aim of this study was to evaluate the feasibility of a subsequent fully powered, randomized controlled trial. Methods: The study was designed as a randomized, observer-blind trial. Both interventions were provided for up to one hour a day, four days a week, for six weeks. Evaluation points were before randomization (baseline), after six weeks intervention (outcome), and six weeks thereafter (follow-up). The study took place in participantsā€™ own homes. Participants (nā€‰=ā€‰52) were a mean of 24.4 months after stroke with a mean age of 68.3 years with 67.3% male. All had difficulty using their paretic upper (UL) and lower limb (LL). Participants were allocated to FST-UL or FST-LL by an independent randomization service. The outcome measures were recruitment rate, attrition rate, practicality of recruitment strategies, occurrence of adverse reactions, acceptability of FST, and estimation of sample size for a subsequent trial. Primary clinical efficacy outcomes were the Action Research Arm Test (ARAT) and the Functional Ambulation Categories (FAC). Analysis was conducted using descriptive statistics and thematic analysis of participantsā€™ views of FST. A power calculation used estimates of clinical efficacy variance to estimate sample size for a subsequent trial. Results: The screening process identified 1,127 stroke survivors of whom 52 (4.6%) were recruited. The recruitment rate was higher for referral from community therapists than for systematic identification of people discharged from an acute stroke unit. The attrition rate was 15.5% at the outcome and follow-up time-points. None of the participants experienced an adverse reaction. The participants who remained in the study at outcome had received 68% of the total possible amount of therapy. Participants reported that their experience of FST provided a sense of purpose and involvement and increased their confidence in performing activities. The power calculation provides estimation that 150 participants in each group will be required for a subsequent clinical trial. Conclusions: This study found that a subsequent clinical trial was feasible with modifications to the recruitment strategy to be used

    Uptake of hepatitis C specialist services and treatment following diagnosis by dried blood spot in Scotland

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    Background: Dried blood spot (DBS) testing for hepatitis C (HCV) was introduced to Scotland in 2009. This minimally invasive specimen provides an alternative to venipuncture and can overcome barriers to testing in people who inject drugs (PWID). Objectives: The objective of this study was to determine rates and predictors of: exposure to HCV, attendance at specialist clinics and anti-viral treatment initiation among the DBS tested population in Scotland. Study design: DBS testing records were deterministically linked to the Scottish HCV Clinical database prior to logistic regression analysis. Results: In the first two years of usage in Scotland, 1322 individuals were tested by DBS of which 476 were found to have an active HCV infection. Linkage analysis showed that 32% had attended a specialist clinic within 12 months of their specimen collection date and 18% had begun anti-viral therapy within 18 months of their specimen collection date. A significantly reduced likelihood of attendance at a specialist clinic was evident amongst younger individuals (<35 years), those of unknown ethnic origin and those not reporting injecting drug use as a risk factor. Conclusion: We conclude that DBS testing in non-clinical settings has the potential to increase diagnosis and, with sufficient support, treatment of HCV infection among PWID

    The experience of teasing in elective cosmetic surgery patients

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    The role of teasing as a motivator for patients undertaking elective cosmetic surgery was investigated. Pre-operative data were collected, using a range of standardized tests in addition to open ended questions about their experience of teasing, from 449 patients aged 18 to 70 undergoing elective cosmetic surgery in Australia. Just under half of the sample indicated that they had been teased or bullied about their appearance. Teased patients showed significantly higher levels of anxiety, depression and dysmorphic concern; lower levels of physical attractiveness and appearance satisfaction; and lower levels of satisfaction with discrete aspects of their appearance than nonteased patients. Teasing also contributed to longer periods of considering surgery as an answer to body dissatisfaction concerns, even when controlling for age. Prevention education initiatives on appearance-related teasing should be targeted at school students. This, along with earlier detection of the psychological impacts of weight and appearance-related teasing, fewer people, if offered strategies for coping through counseling, may contemplate surgery as a response to this teasing

    Emotion regulation and residual depression predict psychosocial functioning in bipolar disorder: Preliminary study

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    This study explores the predictive value of various clinical, neuropsychological, functional, and emotion regulation processes for recovery in Bipolar Disorder. Clinical and demographic information was collected for 27 euthymic or residually depressed BD participants. Seventy one percent of the sample reported some degree of impairment in psychosocial functioning. Both residual depression and problems with emotion regulation were identified as significant predictors of poor psychosocial functioning. In addition, to residual depression, the results of the current study introduce a variable of emotion dysregulation to account for poor psychosocial functioning among BD populations. Improving emotion regulation strategies, in particular, concentration and task accomplishment during negative emotional states could have important consequences for improving overall psychosocial functioning among this population, helping to reduce both the economic burden and high costs to personal wellbeing associated with B

    Emotion regulation in bipolar disorder: Are emotion regulation abilities less compromised in euthymic bipolar disorder than unipolar depressive or anxiety disorders?

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    This study investigated the profile of emotion dysregulation in Bipolar Disorder (BD) and com- pared it to Unipolar Depression, Anxiety, and Heal- thy control groups. Methods: 148 euthymic patients diagnosed with BD (n = 48), Unipolar Depressive dis- order (n = 50), Anxiety disorder (n = 50), and a Healthy Control (HC) group (n = 48) were evaluated using the Difficulties in Emotion Regulation Scale (DERS). The DERS yields a total score in addition to scores on six subcomponents believed to encapsulate the emotion dysregulation construct. Results: Com- pared to the healthy control group, all clinical groups (BD, Unipolar Depression, and Anxiety) reported significantly greater overall difficulties in emotion re- gulation (Total DERS) and difficulties specific to the DERS subcomponent measures: Goals, Impulse, and Strategies. The profile of emotion dysregulation was virtually identical for the Unipolar Depression and Anxiety groups, with BD demonstrating emotion regulation difficulties intermediate between controls and the two clinical groups. Specifically, emotion re- gulation in the BD group was significantly less com-promised in the domains of acceptance of emotions, emotional awareness, and emotional clarity com- pared to the depression and anxiety groups. Conclu- sions: Emotion regulation abilities among people with euthymic BD were significantly less compromised than Unipolar Depression and Anxiety groups with regards to emotional awareness, acceptance of emo- tions, and understanding of emotions. However, emo- tion regulation abilities pertaining to engagement in goal directed behaviour, impulse control, and access to emotion regulation strategies were similarly com- promised across all three clinical groups. This profile might help enrich extant adjunct psychological in- terventions for BD by enlisting emotion regulation strategies with the aim of decreasing the relapse rate that characterises BD

    A decision support tool for parasite management in fish aquaculture

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    A decision support tool was developed to aid management of problematic parasites in marine fish aquaculture. The tool provides biologically relevant treatment intervals to interrupt the life cycle of ectoparasitic flatworms that occur in global kingfish and amberjack (Seriola spp.) aquaculture. Temperature-dependent life cycle parameters for the ā€˜skin flukesā€™, Benedenia seriolae and Neobenedenia girellae, and the ā€˜gill flukeā€™, Zeuxapta seriolae, were derived from published data and modelled using non-linear regressions. Increasing temperatures shortened the duration of most life cycle parameters of all parasites. Salinity had no effect on the timing of life cycle parameters but limited hatching success in hypo- and hypersaline conditions. The tool, named BeNeZe after the first two letters of each parasite genera, enables rapid determination of treatment intervals for two consecutive medicinal immersion or ā€˜bathingā€™ treatmentsā€”the first to kill adult flatworms attached to fish and the second to prevent maturity of new parasite recruits. As temperature increases, the interval between treatments and the ā€˜windowā€™ within which the second treatment should be applied is reduced. The tool can be used for multi-species infections. The inclusion of parasite taxonomy, biology and behaviour as part of an integrated management strategy is reviewed. Available through an open access app, BeNeZe is intended to be applied in conjunction with farm biosecurity, surveillance, management measures and recognition of independent management units. BeNeZe can be used to reduce infection burdens, improve fish welfare and production and reduce treatment number and frequency
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