17 research outputs found
Tenth, 25<sup>th</sup>, 50<sup>th</sup>, 75<sup>th</sup>, and 90<sup>th</sup> percentiles of HCV RNA level in relation to <i>IL28B</i>.
<p>Tenth, 25<sup>th</sup>, 50<sup>th</sup>, 75<sup>th</sup>, and 90<sup>th</sup> percentiles of HCV RNA level in relation to <i>IL28B</i>.</p
Study enrollment and disposition of patients.
<p>Study enrollment and disposition of patients.</p
Baseline characteristics of patients with a valid liver stiffness measurement.
<p>Values are expressed as n<sup>a</sup>, median (IQR)<sup>b</sup> or percentage<sup>e</sup></p>c<p>n = 318, n = 34, and n = 91 for genotype 1, 2, and 3 respectively</p>d<p>n = 152, n = 6, and n = 51 for genotype 1, 2, and 3 respectively</p
Frequency distribution of <i>IL28B</i> variants in relation to HCV genotypes 1-3 among treatment-naïve patients.
<p>Chi-squared (<i>χ</i><sup>2</sup>)-test was used to compare differences in distribution.</p
Tenth, 25<sup>th</sup>, 50<sup>th</sup>, 75<sup>th</sup>, and 90<sup>th</sup> percentiles of APRI score in relation to <i>IL28B</i> variants for genotypes 1, 2 and 3.
<p>Tenth, 25<sup>th</sup>, 50<sup>th</sup>, 75<sup>th</sup>, and 90<sup>th</sup> percentiles of APRI score in relation to <i>IL28B</i> variants for genotypes 1, 2 and 3.</p
Baseline characteristics according to HCV genotype and IL28 B genetic variations (<i>rs12979860</i>).
<p>Values are expressed as median (IQR)<sup>a</sup> or n<sup>b</sup></p>c<p>n = 173 genotype 1, n = 58 genotype 3</p>d<p>n = 373 genotype 1, n = 109 genotype 3</p
Impact of <i>IL28B</i> (<i>rs12979860</i>) on normalized ALT and AST to platelet ratio index (APRI) among HCV genotype 2 and 3 infected patients.
<p>Box plots displaying the 10<sup>th</sup>, 25<sup>th</sup>, 50<sup>th</sup>, 75<sup>th</sup>, and 90<sup>th</sup> percentiles and p-values obtained using Kruskal-Wallis test.</p
Baseline Characteristics with Patients Grouped According to HCV genotype and <i>IL28B</i> Genetic Variations (<i>rs12979860</i>).
<p>Data presented as median (25<sup>th</sup>–75th percentile)<sup>a</sup> or n<sup>b</sup>.</p
Association between <i>IL28B</i> (<i>rs12979860</i>) and portal inflammation grade (Ishak protocol) and steatosis grade among HCV genotype 2 and 3 infected patients.
<p>Histogram displaying the proportion of patients, and p-value obtained using Chi-squared test.</p
Impact of <i>IL28B</i> (<i>rs12979860</i>) on baseline viral load and decline in mean HCV RNA day 0–3 among HCV genotype 2 and 3 infected patients.
<p>Box plots displaying the 10<sup>th</sup>, 25<sup>th</sup>, 50<sup>th</sup>, 75<sup>th</sup>, and 90<sup>th</sup> percentiles, and p-values obtained using Kruskal-Wallis test.</p