Fully differential Vector-Boson Fusion Higgs Pair Production at Next-to-Next-to-Leading Order

We calculate the fully differential next-to-next-to-leading order (NNLO) QCD corrections to vector-boson fusion (VBF) Higgs pair production. This calculation is achieved in the limit in which there is no colored cross-talk between the colliding protons, using the projection-to-Born method. We present differential cross sections of key observables, showing corrections of up to 3-4% at this order after typical VBF cuts, with the total cross section receiving contributions of about 2%. In contrast to single Higgs VBF production, we find that the NNLO corrections are for the most part within the next-to-leading order scale uncertainty bands.Comment: 5 pages, 3 figures, updated to match published versio

Vector-Boson Fusion Higgs Pair Production at N3^3LO

We calculate the next-to-next-to-next-to-leading order (N$^3$LO) QCD corrections to vector-boson fusion (VBF) Higgs pair production in the limit in which there is no partonic exchange between the two protons. We show that the inclusive cross section receives negligible corrections at this order, while the scale variation uncertainties are reduced by a factor four. We present differential distributions for the transverse momentum and rapidity of the final state Higgs bosons, and show that there is almost no kinematic dependence to the third order corrections. Finally we study the impact of deviations from the Standard Model in the trilinear Higgs coupling, and show that the structure of the higher order corrections does not depend on the self-coupling. These results are implemented in the latest release of the proVBFH-incl program.Comment: 10 pages, 9 figures, updated to match published versio

Continuous growth reference from 24th week of gestation to 24 months by gender

<p>Abstract</p> <p>Background</p> <p>Growth charts and child growth assessment have become prime global instruments in child health practice over the 30 years. An updated, continuous growth standard that bridges size at birth values with postnatal growth values can improve child growth screening and monitoring.</p> <p>Methods</p> <p>This novel growth chart was constructed from two sources of information. Size at birth (weight, length and head circumference) reference values were updated based on information of normal deliveries (i.e. singleton live births without severe congenital malformation, with healthy mothers and born vaginally) from the Swedish Medical Birth Registry, 1990–1999 (n = 810393). Weight was evaluated using logarithmic transformation as for postnatal weight. Standard deviations were estimated from data within the empirical mean ± 1.0 SD for each gestational week and gender. These values were smoothed by empirical curve-fitting together with values from our recently published postnatal growth reference including 3650 longitudinally followed children from birth to final height <abbrgrp><abbr bid="B9">9</abbr></abbrgrp>. Timescale and weight axes were made logarithmic in order to magnify the early time part of the graph.</p> <p>Results</p> <p>This study presents the first continuous gender specific growth chart from birth irrespective of gestational age at birth until 2 years of age for weight, length and head circumference. Birth weight at 40 weeks of gestation increased approximately 100 gram and length increased only 1 mm compared with earlier Swedish reference from 1977–81. The curve is now less S-shaped as compared with earlier curves and compared with 4 curves from other countries and with more constant variation over the whole range.</p> <p>Conclusion</p> <p>Our values picture the unrestricted pattern of growth improving the detection of a deviating growth pattern, when the growth of an individual infant is plotted on the charts. Especially for very preterm infants age corrected growth can be more easily evaluated although it must be recognized that the early comparison is with what is estimated as normal growth in uterus. The reference values are useful in child health care systems for population screening, but also in research or in the clinic for evaluating various growth promoting interventions – either nutritional, surgical or therapeutic – that might affect a child in early life.</p

The Lantern Vol. 48, No. 2, May 1982

• Atonement to the Clown • 5 A.M. • Les Moulins a Vent • Isn\u27t It a Bitter Cold • Eyes That Want • I Am a Life Saver • The Death of Chicken Little • The Secret • In a Little Jungle • Night • From Foundlings • Night Was My Friend • The Librarian of Langden Hall • The Heart • Daybreak • City Song • Chance • Cotton Panels • To Phlebas • Attraction • Fall • Coming Home • June • Breaking Free • Mother • Ice Tree • Return from Nhatrang • What It All Comes Down To • To Benjamin • The Light • Piano Practice • Mother\u27s Song to Her Son • Sister\u27s Song • Shopping • Grandfather • Closing Statement • Dreaming • Another Sunset • Clear, Cold and Crystal • Jog!!! • Empty Nightshttps://digitalcommons.ursinus.edu/lantern/1120/thumbnail.jp

Restriction of lung volumes but normal function of pulmonary tissue in mulibrey nanism

Background Mulibrey nanism (MUL) is a rare growth restriction disorder with multiple organ manifestations caused by genetic defects affecting the TRIM37 protein. A perimyocardial heart disease is the most serious manifestation. Many MUL children appear to suffer from airway obstruction related to infection or exercise, prompting use of inhaled therapies. Asthma medication is continued up to adolescence or even to adulthood due to persisting of symptoms. The pulmonary pathophysiology has previously not been evaluated in any MUL cohort. Methods Thirty three finnish MUL patients (median age 20 years) were investigated with several lung function tests: spirometry with bronchodilatation test, single-breath diffusing capacity for carbon monoxide, single-breath lung volume measurements with helium dilution, and thoracic gas volume, airway resistance and specific conductance measurements with a body plethysmograph. As MUL typically affects body proportions, all variables were compared with reference values and with predicted values calculated from sitting height. Results Total lung capacity and forced vital capacity were markedly reduced (total lung capacity [TLC] and forced vital capacity [FVC], P = 12% and >= 200 mL) was found only in one patient. Conclusion MUL patients typically have volume restriction of the lungs, but function of the pulmonary tissue remains intact. Evidence of asthma in lung function testing at adult age is rare.Peer reviewe

Accuracy of self-reported height measurements in parents and its effect on mid-parental target height calculation

BACKGROUND: Clinical determination of mid-parental height is an important part of the assessment of a child's growth, however our clinical impression has been that parents cannot be relied upon to accurately report their own heights. Therefore, we conducted this study to assess the accuracy of parental height self-reporting and its effect on calculated mid-parental target height for children presenting to a pediatric endocrinology office. METHODS: All parents bringing their children for an initial evaluation to a pediatric endocrinology clinic over a period of nine months were questioned and then measured by a pediatric endocrinologist. Parents were blinded to the study. Mid-parental target heights, based on reported and actual height were compared. RESULTS: There were 241 families: 98 fathers and 217 mothers in our study. Mean measured paternal height was 173.2 cm, self reported 174.9 cm (p < 0.0001), partner reported 177 cm (p = 0.0004). Only 50% of fathers and 58% of mothers reported their height within ± 2 cm of their measured height, while 15% of fathers and 12% of mothers were inaccurate by more than 4 cm. Mean measured maternal height was 160.6 cm, self-reported 161.1 cm (NS), partner reported 161.7 cm (NS). Inaccuracy of height self-report had a small but significant effect on the mean MPTH (0.4 cm, p = 0.045). Analysis showed that only 70% of MPTH calculated by reported heights fell within ± 2 cm of MPTH calculated using measured heights, 24% being in ± 2–4 cm range, and 6% were inaccurate by more than 4 cm. CONCLUSION: There is a significant difference in paternal measured versus reported heights with an overall trend for fathers to overestimate their own height. A large subset of parents makes a substantial error in their height self-report, which leads to erroneous MPTH. Inaccuracy is even greater when one parent reports the other parent's height. When a child's growth is in question, measured rather than reported parental heights should be obtained

Precise predictions for double-Higgs production via vector-boson fusion.

Theoretical predictions with next-to-next-to-leading order (NNLO) QCD accuracy combined with the next-to-leading order (NLO) electroweak (EW) corrections are presented for differential observables of the double-Higgs production process via vector-boson fusion. While the QCD corrections were previously known, the EW ones are computed here for the first time. The numerical results are obtained for a realistic experimental set-up at the LHC and are presented in the form of fiducial cross sections and differential distributions. Within this setup we find that the VBF approximation employed in the NNLO QCD correction is accurate at the sub-percent level. We find that the NLO EW corrections within the fiducial volume are - 6.1 % , making them of almost the same order as the NLO QCD corrections. In some kinematic regions they can grow as large as - 30 % making them the dominant radiative corrections. When the EW corrections are combined with the NNLO QCD corrections we find a total correction of - 14.8 % . The results presented here thus comprise the state-of-the-art theoretical predicition for the double-Higgs production via vector-boson fusion, which will be of value to the high-luminosity programme at the LHC

BMI Changes During Childhood and Adolescence as Predictors of Amount of Adult Subcutaneous and Visceral Adipose Tissue in Men: The GOOD Study

Objective. The amount of visceral adipose tissue is a risk factor for the metabolic syndrome. It is unclear how body mass index (BMI) changes during childhood and adolescence predict adult fat distribution. We hypothesized that there are critical periods during development for the prediction of adult subcutaneous and visceral fat mass by BMI changes during childhood and adolescence. Research Design and Methods. Detailed growth charts were retrieved for the men participating in the population-based Gothenburg Osteoporosis and Obesity Determinants (GOOD) study (n=612). Body composition was analysed using Dual X-Ray Absorptiometry and adipose tissue areas using abdominal computed tomography at 18-20 years of age. Results. The main finding in the present study was that subjects with increases in BMI Z-score of >1 SD during adolescence had, independent of prepubertal BMI, both larger subcutaneous (+138%; p1 SD during late childhood had larger amount adult subcutaneous adipose tissue (+83%;