Association of serum adipokine tertiles with the presence of a hyperplastic polyp.

<p>Note: Model is adjusted for age and ever/never smoked.</p

Pearson correlation coefficients.

<p>Note: The top number is the Pearson correlation coefficient. The P values are shown under the correlation coefficient.</p

sRAGE is inversely related to the presence of diverticulosis.

<p>Males with serum sRAGE concentrations between 94.5 and 120.4/ml were 0.5 (CI: 0.2–1.2) less likely to have diverticulosis, and males with sRAGE concentrations above 120.4 pg/ml were 0.2 (CI: 0.08–0.5) times less likely to have diverticulosis than those with sRAGE concentrations below 94.5 pg/ml. For each tertile increase in serum sRAGE, the odds of having diverticulosis decreased by 0.4 (CI: 0.3–0.7) times.</p

Association of biomarker patterns with diverticulosis.

<p>Association of biomarker patterns with diverticulosis.</p

Association of BMI with the presence or severity of polyps in the proximal^† or distal^†† colon.

<p>Note: Model is adjusted for age and ever/never smoked.</p><p>Proximal (right) colon included: cecum, ascending colon, and transverse colon</p><p>Distal (left) colon included: descending colon, sigmoid colon, and rectum</p

Participant^† Characteristics.

<p>All participants (n = 126) were male, >96% Caucasian</p><p>Reported as mean (range)</p

Association of serum adipokine tertiles with the presence of a tubular adenoma.

<p>Note: Model is adjusted for age and ever/never smoked.</p

BMI is associated with polyp number (A) as well as the presence of tubular adenoma (B).

<p>A, Compared to lean males, obese males (BMI ≥30) are 6.5 times more likely to have ≥3 polyps. In addition, for each category increase in BMI, a man is 2.5 times more likely to have ≥3 polyps than no polyps. B, Compared to lean males, obese males are 7.8 times more likely to have a tubular adenoma. For each category increase in BMI, a man is 2.9 times more likely to have a tubular adenoma. The model was adjusted for age and smoking status (ever/never).</p

Association of serum adipokine tertiles with having ≥3 polyps.

<p>Note: Model is adjusted for age and ever/never smoked.</p

Leptin is positively associated with the presence of diverticulosis.

<p>Individuals who had serum leptin concentrations between 4.5 and 9 ng/ml were 2.1 (CI: 0.8–5.6) times more likely and those with concentrations above 9 ng/ml were 5.5 (CI: 2.0–14.7) times more likely to have diverticulosis than individuals with serum concentrations below 4.5 ng/ml. For each tertile increase in serum leptin concentration the risk of having diverticulosis increased 2.4 (CI: 1.4–3.9) times.</p