2 research outputs found

    Lighting Assessment in Knitting Workshop in Yazd

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    Introduction: The sense of sight is one of the most vital human senses and help the environment gets most of its information. Whatever one's job is more subtle, more work will be given brightness. Good lighting, increase work efficiency and general physiological effects on people's moods. The relationship between low and high frequency illumination accidents there Methods: This study was conducted in 10 workshops in Yazd home knitting. Due to maximize natural lighting measurements in June and November this year took place in cloudy days. Thus, in both seasons overall lighting, natural and artificial, were evaluated. That, in order to measure all the natural light, artificial light sources (lamps) and the measurements were off by clarifying re-lamp, the overall lighting (natural and artificial) were measured. In order to measure the general lighting provided by the Illuminating Engineering society and stop the pattern surfaces were used. The workshops with less than standard lighting conditions were identified and interventions to improve the brightness of the workshops were measured again. Results: Average, minimum and maximum overall brightness of spring workshops 4 and 6 respectively, with values of 67/278 and 53/452 is a luxury. Workshops values 5 and 2 47/184 and 43/218 minimum and maximum luxury in order to be daylight in spring. Conclusions: The majority of the studied weaving Workshops lighting was good, with measures such as proper installation and periodic cleaning and dust lamps, replacement lamps burned by use of fluorescent ambient lighting conditions can be improved

    Assessment of adaptive response of gamma radiation in the operating room personnel exposed to anesthetic gases by measuring the relative gene expression changes KU80, LIGASE1 and P53

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    Background: Some operating room personnel are occupationally exposed to genotoxic agents such as anesthetic gases and ionizing radiation. Adaptive response, as a defense mechanism, will occur when cells become exposed to a low dose of factors harming DNA (priming dose), which in the subsequent exposure to higher dose of those factors (challenging dose), show more resistance and sensibility. Objective: The aim of this study was to investigate adaptive response or synergy of ionizing radiation in the operating room personnel exposed to anesthetic gases by evaluation of the relative gene expression changes of effective genes for DNA repair such as Ku80, Ligase1 and P53. Material and Methods: In this case-control study, 20 operating room personnel and 20 nurses (who were not present in the operating room) as controls were studied. Venous blood samples were drawn from participants. In order to evaluate the adaptive response, a challenging dose of 2Gy gamma radiation was applied to blood samples. Moreover, RNA extraction and cDNA synthesis were performed. Gene expression level was studied by RT-qPCR and compared with the control group. Results: Ligase1 and P53 expression in the operating room personnel was signifi-cantly higher than that of the control group before irradiation (P�0.001). Statistically, there was no significant difference in the Ku80 and P53 expression in the operating room personnel before and after irradiation. Conclusion: Given the findings of this study, exposure to challenging dose of gamma radiation can induce adaptive response in expression of Ku80 and P53 genes in operating room personnel. © 2020, Shiraz University of Medical Sciences. All rights reserved
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