Renal cortical active IL-18 production following UUO.

<p>Renal cortical active IL-18 protein levels in vehicle treated and macrophage depleted mice exposed to sham operation or one week of UUO.</p

Renal cortical dual labeled immunofluorescent staining for IL-18 and tubular epithelial cells following UUO.

<p><b>A.</b> Photographs (magnification 400X) depicting renal cortical IL-18 production (red) and distal tubular staining (Peanut Agglutinin; green) in vehicle treated and macrophage depleted mice exposed to sham operation or one week of UUO. White arrows indicate IL-18 staining overlying tubules. T = Tubules.</p

Renal cortical macrophage accumulation following UUO.

<p>Photographs (magnification 400X) depicting macrophage (brown stain; arrows) in vehicle treated and macrophage depleted mice exposed to sham operation or one week of UUO. T = tubule; G = glomerulus.</p

Renal cortical dual labeled immunofluorescent staining for IL-18R and tubular epithelial cells following UUO.

<p><b>A.</b> Photographs (magnification 400X) depicting renal cortical IL-18R production (red) and distal tubular staining (Peanut Agglutinin; green) in vehicle treated and macrophage depleted mice exposed to sham operation or one week of UUO. White arrows indicate IL-18R staining overlying tubules. T = Tubules.</p