Design, synthesis and characterization of novel fluorinated styryl chromones

225-228(E)-3-(3-(Trifluoromethyl)-5-nitrophenyl)acrylic acid 1 when treated with substituted 2-hydroxyacetophenones 2 in dry pyridine and POCl3 affords compound 3 which when reacted with pyridine/KOH by B. V. transformation gives 4. Compound 4 on refluxing with acetic acid in HCl gives 5. The structures of all synthesized compounds have been confirmed by spectroscopic techniques

Synthesis and biological screening of some halogenated thiadiazoles and triazoles

89-95 Acid hydrazide 1 is treated with aryl isothiocyanates to get corresponding thiosemicarbazides 2. Compounds 2 in acidic medium give thiadiazoles 3 and in basic medium give triazoles 4. These compounds are synthesized by conventional method and ultra sound irradiation method. Some of the synthesized compounds are tested for their antimicrobial, antiviral and antioxidant activities. </smarttagtype

<span style="font-size:10.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-bidi-font-family: Mangal;mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language: HI" lang="EN-US">Synthesis and <i style="mso-bidi-font-style:normal">in vitro</i> biological screening of some benzimidazolyl anchored azoles</span>

399-405A series of novel thiadiazoles and triazoles anchored with benzimidazole have been synthesized and evaluated for their biological activities

Synthesis of 3-[2-(4-nitrophenyl)­vinyl]­chromon-4-one by ultrasonic irradiation

1522-1523Various 3-[2-(4-nitrophenyl)vinyl]chromon-4-ones have been synthesized by ultrasonic activation from corresponding 3-formylchromones and 4-nitrophenylacetic acid

Synthesis and biological screening of some novel fluorinated chromones and aurones

434-438Novel trifluoro pyrazolyl chromones and aurones containing thiophene moiety have been synthesized, characterized and screened for their antibacterial, antifungal, antiviral and antioxidant activities

Synthesis, characterisation and antimicrobial screening of some new thiazolyl chromones and pyrazoles

916-920A series of substituted chromones and pyrazole derivatives have been synthesized from esterification of acid 1 with 2-hydroxy acetophenones 2 to give compounds 3 which is in turn converted in to &beta;-diketones 4 in presence of excess of KOH by Baker-Venkatraman transformation. Acid catalysed cyclisation of &beta;-diketones 4 yield a series of 2-substituted chromones 5. 2-Substituted chromones 5 have been used to synthesise substituted pyrazole derivatives 6. All the synthesised compounds have been characterised by spectral and analytical data. Chromones and pyrazoles have been evaluated for their antibacterial and antifungal activities

Ant colony framework for optimal design and scheduling of batch plants

This paper presents a new co-operative search approach, the ant colony optimisation paradigm, for the optimal design of batch chemical processes and illustrates it by solving (1) the combinatorial optimisation problem of multiproduct batch scheduling and (2) the continuous function optimisation problem for the design of multiproduct batch plant with single product campaigns and horizon constraints. The ant algorithm is simple to implement and results of the case studies show its ability to provide speedy and accurate solutions

Synthesis and characterization of thiazole anchored fluorinated 2-heterylchromones and pyrazoles

458-462Esterification of 2-(4-fluorophenyl)-4-methylthiazole-5-carboxylic acid 4 with 2-hydroxyacetophenones 5 yields compounds 6 which have been converted to &beta;-diketones 7 by Baker-Venkataraman transformation. A series of 2-substituted chromones 8 have been obtained by acid catalysed intramolecular cyclization of &beta;-diketones. Substituted pyrazoles 9 have been obtained from &beta;-diketones 7. Formation of all the synthesized compounds have been confirmed by the spectroscopic techniques

Conventional and Ultrasound Mediated Synthesis of Some Thiadiazoles, Triazoles and Oxadiazoles.

2776-2780Acid hydrazide 1 when treated with aryl isothiocyanates gives the compounds 2. These compounds 2 on ultrasound irradiation in acidic medium give compounds 3 i.e. thiadiazoles and in basic medium gives compounds 4 i.e. triazoles. These compounds 2 on treatment with I2/KI and NaOH resulted in compounds 5 i.e. oxadiazoles. These compounds are synthesized by conventional method as well as ultra sound irradiation method

Ant colony approach to continuous function optimization

An ant colony optimization framework has been compared and shown to be a viable alternative approach to other stochastic search algorithms. The algorithm has been tested for variety of different benchmark test functions involving constrained and unconstrained NLP, MILP, and MINLP optimization problems. This novel algorithm handles different types of continuous functions very well and can be successfully used for large-scale process optimization