Adiponectin gene SNP 276G → T, nutrient intakes, and cardiovascular disease risk in Korean type 2 DM patients

Single nucleotide polymorphism (SNP) in adiponectin gene has been associated with insulin resistance, diabetes, and cardiovascular disease (CVD). This study was performed to investigate the association of SNP 276G→T at adiponectin gene with CVD risk factors in Korean type 2 diabetes mellitus (DM) patients. The subjects were 351 type 2 DM patients visited a DM clinic in Seoul, and the patients with known CVD were excluded. The adiponectin SNP 276G→T was analyzed and dietary intakes were assessed by a Food Frequency Questionnaire. The prevalence of G/G, G/T, and T/T genotype was 47.6%, 43.3%, and 9.1%, respectively. Male subjects with T/T genotype showed significantly lower level of adiponectin and HDL-cholesterol and significantly higher C-reactive protein (CRP) level compared to G/G and G/T genotypes. In G/G genotype, protein intake was negatively correlated to body weight, BMI, and waist circumference, and there were positive correlation between carbohydrate intake and BMI, waist-hip ratio, and ApoB/apoA-1 ratio in G/T genotype. However, in T/T genotype, there was no significant association between macronutrient intakes and anthropometric and hematological values. In conclusion, CVD risk would be high in type 2 DM patients with T/T genotype, and the association of macronutrient intakes with anthropometric and hematologic factors was different among the three adiponectin genotypes. These results may imply the need for different dietary management regime according to adiponectin genotype to lower CVD complications in Korean type 2 DM patients

A modified technique for the calibration of a current-comparator-based high voltage capacitance bridge and its comparison between KRISS and NRC

A modified technique for calibrating both the capacitance ratio and dissipation factor (DF) dials of a current-comparator-based high voltage capacitance bridge (CCB-HVCB) has been developed at KRISS. The capacitance ratio and DF dials are calibrated, respectively, in the ratio range from 1/1 to 100/1 and in DF range from 10 \uc3\u2014 10-6 to 1 \uc3\u2014 10-1. From the calculated and measured values of the corresponding dial balanced readings, the errors in the capacitance ratio an DF dial readings can be derived. This modified calibration technique has been implemented on a commercial version of a NRC developed CCB-HVCB. The comparison results of the calibration performed at KRISS and NRC will be presented and discussed.Peer reviewed: YesNRC publication: Ye

A comparison of systems between KRISS and NRC to evaluate performance characteristics of a 400 kV capacitive voltage divider

KRISS has established a reference 400 kV capacitive voltage divider for the purpose of calibrating industrial high voltage measuring systems on-site. In order to confirm the performance characteristics of the divider, a comparison of the calibration systems between KRISS and NRC with the divider used as the transfer standard was conducted. The paper presents the comparison results of its performance evaluations.Peer reviewed: YesNRC publication: Ye

Evaluating the Effectiveness of Cryopreserved Acellular Dermal Matrix in Immediate Expander-Based Breast Reconstruction: A Comparison Study

Background CGCryoDerm was first introduced in 2010 and offers a different matrix preservation processes for freezing without drying preparation. From a theoretical perspective, CGCryoDerm has a more preserved dermal structure and more abundant growth factors for angiogenesis and recellularization. In the current study, the authors performed a retrospective study to evaluate freezing- and freeze-drying-processed acellular dermal matrix (ADM) to determine whether any differences were present in an early complication profile. Methods Patients who underwent ADM-assisted tissue expander placement for two stage breast reconstruction between January of 2013 and March of 2014 were retrospectively reviewed and divided into two groups based on the types of ADM-assisted expander reconstruction (CGDerm vs. CGCryoDerm). Complications were divided into four main categories and recorded as follows: seroma, hematoma, infection, and mastectomy skin flap necrosis. Results In a total of 82 consecutive patients, the CGCryoDerm group had lower rates of seroma when compared to the CGDerm group without statistical significance (3.0% vs. 10.2%, P=0.221), respectively. Other complications were similar in both groups. Reconstructions with CGCryoDerm were found to have a significantly longer period of drainage when compared to reconstructions with CGDerm (11.91 days vs. 10.41 days, P=0.043). Conclusions Preliminary findings indicate no significant differences in early complications between implant/expander-based reconstructions using CGCryoderm and those using CGDerm

A New Method to Improve Detection of Co-seismic Ionospheric Disturbances Using Sequential Measurement Combination

International audienceEarthquakes generate energy that propagates into the ionosphere and incurs co-seismic ionospheric disturbances (CIDs), which can be observed in ionospheric delay measurements. In most cases, the CID has a weak signal strength because the energy in the atmosphere transferred from the earthquake dissipates as it travels toward the ionosphere. It is particularly hard to observe at reference stations that are located far from the epicenter. As the number of Global Navigation Satellite System stations and their positions are restricted, it is important to employ weak CID data in the analysis by improving the detection performance of CIDs. In this study, we suggest a new method to detect CIDs, which mainly uses sequential measurement combination of the carrier phase-based ionospheric delay data with a 1-second interval. The proposed method's performance was compared with conventional methods, including band-pass filters and a representative time-derivative method, through data from the 2011 Tohoku earthquake. As a result, the maximum CID-to-noise ratio can be increased by a maximum of 13% when the proposed method is used, and consequently, the detection performance of the CID can be improved