9 research outputs found
A Risk Prediction Model and Risk Score of SARS-CoV-2 Infection Following Healthcare-Related Exposure
Hospital workers are at high risk of contact with COVID-19 patients. Currently, there is no evidence-based, comprehensive risk assessment tool for healthcare-related exposure; so, we aimed to identify independent factors related to COVID-19 infection in hospital workers following workplace exposure(s) and construct a risk prediction model. We analyzed the COVID-19 contact tracing dataset from 15 July to 31 December 2021 using multiple logistic regression analysis, considering exposure details, demographics, and vaccination history. Of 7146 included exposures to confirmed COVID-19 patients, 229 (4.2%) had subsequently tested positive via RT-PCR. Independent risk factors for a positive test were having symptoms (adjusted odds ratio 4.94, 95%CI 3.83–6.39), participating in an unprotected aerosol-generating procedure (aOR 2.87, 1.66–4.96), duration of exposure >15 min (aOR 2.52, 1.82–3.49), personnel who did not wear a mask (aOR 2.49, 1.75–3.54), exposure to aerodigestive secretion (aOR 1.5, 1.03–2.17), index patient not wearing a mask (aOR 1.44, 1.01–2.07), and exposure distance <1 m without eye protection (aOR 1.39, 1.02–1.89). High-potency vaccines and high levels of education protected against infection. A risk model and scoring system with good discrimination power were built. Having symptoms, unprotected exposure, lower education level, and receiving low potency vaccines increased the risk of laboratory-confirmed COVID-19 following healthcare-related exposure events
Comparisons between bacteremia patients with community-acquired infection and bacteremia patients with hospital-acquired infection.
<p>Comparisons between bacteremia patients with community-acquired infection and bacteremia patients with hospital-acquired infection.</p
Organisms isolated from all blood specimens from all admissions of all included patients.
<p>Organisms isolated from all blood specimens from all admissions of all included patients.</p
Causative and contaminant bacteria isolated from all blood specimens from all admissions of all included patients.
<p>Causative and contaminant bacteria isolated from all blood specimens from all admissions of all included patients.</p
Comparisons between patients who received concordant empirical antibiotic therapy and patients who received non-concordant empirical antibiotic therapy.
<p>Comparisons between patients who received concordant empirical antibiotic therapy and patients who received non-concordant empirical antibiotic therapy.</p
Percentage of antibiotic susceptibility of common or important community-acquired bacterial isolates (CABI) and hospital-acquired bacterial isolates (HABI).
<p>Percentage of antibiotic susceptibility of common or important community-acquired bacterial isolates (CABI) and hospital-acquired bacterial isolates (HABI).</p
In-hospital mortality of patients with priority pathogens as the cause of bacteremia.
<p>In-hospital mortality of patients with priority pathogens as the cause of bacteremia.</p
Comparisons between patients with primary bacteremia and patients with secondary bacteremia.
<p>Comparisons between patients with primary bacteremia and patients with secondary bacteremia.</p