ZrCl₄-Catalyzed C-O Bond to C-N Bond Formation: Synthesis of 1,2,3-Triazoles and Their Biological Evaluation

<div><p></p><p>A simple and efficient protocol was developed for the synthesis of aryl azides directly from aryl carbinols using ZrCl₄ as a Lewis acid catalyst. The azides were converted to novel triazoles under click reaction conditions, which were evaluated for their antimicrobial activity against various strains.</p> </div