16 research outputs found
ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠΎΡΡΠ°Π²Π° ΠΈ ΡΠ²ΠΎΠΉΡΡΠ² Π½Π΅ΡΡΠ΅ΠΉ ΠΌΠ΅ΡΡΠΎΡΠΎΠΆΠ΄Π΅Π½ΠΈΠΉ ΠΠ°ΠΏΠ°Π΄Π½ΠΎΠΉ Π‘ΠΈΠ±ΠΈΡΠΈ
Π Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΠ΅ Π²ΡΠΏΠΎΠ»Π½Π΅Π½Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π² ΠΎΠ±Π»Π°ΡΡΠΈ ΡΠΎΡΡΠ°Π²Π° ΠΈ ΡΠ²ΠΎΠΉΡΡΠ² Π²ΡΡΠΎΠΊΠΎΠΏΠ°ΡΠ°ΡΠΈΠ½ΠΈΡΡΡΡ
Π½Π΅ΡΡΠ΅ΠΉ ΠΌΠ΅ΡΡΠΎΡΠΎΠΆΠ΄Π΅Π½ΠΈΠΉ ΠΠ°ΠΏΠ°Π΄Π½ΠΎΠΉ Π‘ΠΈΠ±ΠΈΡΠΈ. Π¦Π΅Π»Ρ ΡΠ°Π±ΠΎΡΡ: ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠΈΠ·ΠΈΠΊΠΎ-Ρ
ΠΈΠΌΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ²ΠΎΠΉΡΡΠ² Π½Π΅ΡΡΠΈ ΡΠΎ Π²ΡΠ΅ΠΌΠ΅Π½Π΅ΠΌ ΡΠΊΡΠΏΠ»ΡΠ°ΡΠ°ΡΠΈΠΈ ΡΠΊΠ²Π°ΠΆΠΈΠ½ ΠΌΠ΅ΡΡΠΎΡΠΎΠΆΠ΄Π΅Π½ΠΈΠΉ ΠΠ°ΠΏΠ°Π΄Π½ΠΎΠΉ Π‘ΠΈΠ±ΠΈΡΠΈ, Π΄Π»Ρ Π²ΡΠ±ΠΎΡΠ° Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ Π²ΡΠ³ΠΎΠ΄Π½ΠΎΠ³ΠΎ ΠΌΠ΅ΡΠΎΠ΄Π° ΡΡΠ°Π½ΡΠΏΠΎΡΡΠΈΡΠΎΠ²ΠΊΠΈ. ΠΠ»Ρ Π΄ΠΎΡΡΠΈΠΆΠ΅Π½ΠΈΡ ΠΏΠΎΡΡΠ°Π²Π»Π΅Π½Π½ΠΎΠΉ ΡΠ΅Π»ΠΈ ΠΈΠ·ΡΡΠΈΠ»ΠΈ Ρ
ΠΈΠΌΠΈΡΠ΅ΡΠΊΠΈΠΉ ΡΠΎΡΡΠ°Π², ΠΏΡΠΎΠΌΡΡΠ»ΠΎΠ²ΡΡ ΠΏΠΎΠ΄Π³ΠΎΡΠΎΠ²ΠΊΡ Π½Π΅ΡΡΠΈ, ΡΠ°ΡΡΠΌΠΎΡΡΠ΅Π»ΠΈ ΠΏΡΠΎΠ±Π»Π΅ΠΌΡ, Π²ΠΎΠ·Π½ΠΈΠΊΠ°ΡΡΠΈΠ΅ ΠΏΡΠΈ ΠΏΠ΅ΡΠ΅ΠΊΠ°ΡΠΊΠ΅ ΠΈ ΡΠΏΠΎΡΠΎΠ±Ρ ΡΡΠ°Π½ΡΠΏΠΎΡΡΠΈΡΠΎΠ²ΠΊΠΈ ΠΏΠ°ΡΠ°ΡΠΈΠ½ΠΈΡΡΠΎΠΉ Π½Π΅ΡΡΠΈ, ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π»ΠΈ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ΡΠΈΠ·ΠΈΠΊΠΎ β Ρ
ΠΈΠΌΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ²ΠΎΠΉΡΡΠ² ΠΏΠ°ΡΠ°ΡΠΈΠ½ΠΈΡΡΡΡ
Π½Π΅ΡΡΠ΅ΠΉ ΠΠ΅ΡΡ
Π½Π΅-Π‘Π°Π»Π°ΡΡΠΊΠΎΠ³ΠΎ ΠΌΠ΅ΡΡΠΎΡΠΎΠΆΠ΄Π΅Π½ΠΈΡ ΡΠΊΡΠΏΠ»ΡΠ°ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ ΡΠΊΠ²Π°ΠΆΠΈΠ½Ρ β 123.The purpose of the work: study of changes in physical and chemical properties of oil over the time of operation of wells of fields of Western Siberia, in order to choose the most profitable method of transportation. In order to achieve this goal, the chemical composition, field preparation of oil were studied, problems arising during pumping and methods of transportation of paraffinic oil were considered, changes in physical and chemical properties of paraffinic oils of the Verkhne-Salatskoye field of production well No. 123 were investigated
Are anthropogenic factors affecting nesting habitat of sea turtles? The case of Kanzul beach, Riviera Maya-Tulum (Mexico)
Marine coast modification and human pressure affects many species, including sea turtles. In order to study nine anthropogenic impacts that might affect nesting selection of females, incubation and hatching survival of loggerhead (Caretta caretta) and green turtle (Chelonia mydas), building structures were identified along a 5.2 km beach in Kanzul (Mexico). A high number of hotels and houses (88; 818 rooms), with an average density of 16.6 buildings per kilometer were found. These buildings form a barrier which prevents reaching the beach from inland, resulting in habitat fragmentation. Main pressures were detected during nesting selection (14.19% of turtle nesting attempts interrupted), and low impact were found during incubation (0.77%) and hatching (4.7%). There were three impacts defined as high: beach furniture that blocks out the movement of hatchlings or females, direct pressure by tourists, and artificial beachfront lighting that can potentially mislead hatchlings or females. High impacted areas showed lowest values in nesting selection and hatching success. Based on our results, we suggest management strategies to need to be implemented to reduce human pressure and to avoid nesting habitat loss of loggerhead and green turtle in Kanzul, Mexico
Balancing artificial light at night with turtle conservation? Coastal community engagement with light-glow reduction
Artificial lighting is a significant threat to biodiversity. Although efforts to reduce lighting are crucial for species' conservation efforts, management is challenging because light at night is integral to modern society and light use is increasing with population and economic growth. The development and evaluation of appropriate light management strategies will require positive public support, and a comprehensive understanding of public engagement with light pollution. This is the ο¬rst study to examine public engagement with reducing light at night for the protection of a threatened species. A community campaign to reduce artificial light use was initiated in 2008 to protect marine turtles at a globally significant nesting beach. Semi-structured questionnaires assessed community engagement with light-glow reduction, using an existing theoretical constraints framework. Despite high levels of cognitive and affective engagement(knowledge and concern), behavioural engagement(action) with light reduction in this community was limited. Community perceptions of light reduction were dominated by 'uncertainty and scepticism' and 'externalizing responsibility/blame', implying that behavioural engagement in this community may be increased by addressing these widely-held perceptions using modified campaign materials and/or strategic legislation. Further reο¬nement of the theoretical constraints framework would better guide future empirical and conceptual research to improve understanding of public engagement with critical environmental issues
Potential applicability of persuasive communication to light-glow reduction efforts: a case study of marine turtle conservation
Artificial lighting along coastlines poses a significant threat to marine turtles due to the importance of light for their natural orientation at the nesting beach. Effective lighting management requires widespread support and participation, yet engaging the public with light reduction initiatives is difficult because benefits associated with artificial lighting are deeply entrenched within modern society. We present a case study from Queensland, Australia, where an active light-glow reduction campaign has been in place since 2008 to protect nesting turtles. Semi-structured questionnaires explored community beliefs about reducing light and evaluated the potential for using persuasive communication techniques based on the theory of planned behavior (TPB) to increase engagement with light reduction. Respondents (n = 352) had moderate to strong intentions to reduce light. TPB variables explained a significant proportion of variance in intention (multiple regression: R 2 = 0.54β0.69, P < 0.001), but adding a personal norm variable improved the model (R 2 = 0.73β0.79, P < 0.001). Significant differences in belief strength between campaign compliers and non-compliers suggest that targeting the beliefs reducing light leads to "increased protection of local turtles" (P < 0.01) and/or "benefits to the local economy" (P < 0.05), in combination with an appeal to personal norms, would produce the strongest persuasion potential for future communications. Selective legislation and commitment strategies may be further useful strategies to increase community light reduction. As artificial light continues to gain attention as a pollutant, our methods and findings will be of interest to anyone needing to manage public artificial lighting
Twenty years of turtle tracks: marine turtle nesting activity at remote locations in the Pilbara, Western Australia
Measurement of ERK 1/2 in CSF from patients with neuropsychiatric disorders and evidence for the presence of the activated form
The clinical diagnosis of neurodegenerative disorders can be supported by soluble biomarkers in cerebrospinal fluid (CSF), such as tau protein, phospho-tau, and amyloid-beta peptides. In particular, increased CSF levels of phospho-tau in Alzheimer's disease appear to reflect disease specific pathological processes. We report here evidence for the presence of soluble MAP-kinase ERK1/2 in a small set of human CSF samples from patients with Alzheimer's disease, frontotemporal degeneration, and mild cognitive impairment. The level of total ERK1/2 in CSF as measured by electrochemiluminescent assay was correlated with that of total tau and phospho-tau. A small fraction of ERK1/2 in a pooled CSF sample was found to be in the doubly phosphorylated (activated) state. Our findings suggest that i) MAP kinase ERK1/2 is apparently released under neurodegenerative conditions in parallel with tau and phospho-tau and ii) in the future, it might be possible to find in CSF samples evidence for disease related alterations in brain kinase signaling pathways by use of highly sensitive and activation-state specific anti-kinase antibodies
Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study
In this report, we present the results of a multicenter study to test analytic and diagnostic performance of soluble forms of amyloid precursor proteins {alpha} and {beta} (sAPP{alpha} and sAPP{beta}) in the cerebrospinal fluid (CSF) of patients with different forms of dementing conditions. CSF samples were collected from 188 patients with early dementia (mini-mental state examination >or=20 in majority of cases) and mild cognitive impairment (MCI) in 12 gerontopsychiatric centers, and the clinical diagnoses were supported by neurochemical dementia diagnostic (NDD) tools: CSF amyloid{beta} peptides, Tau and phospho-Tau. sAPP{alpha} and sAPP{beta} were measured with multiplexing method based on electrochemiluminescence. sAPP{alpha} and sAPP{beta} CSF concentrations correlated with each other with very high correlation ratio (R=0.96, P<0.001). We observed highly significantly increased sAPP{alpha} and sAPP{beta} CSF concentrations in patients with NDD characteristic for Alzheimer's disease (AD) compared to those with NDD negative results. sAPP{alpha} and sAPP{beta} highly significantly separated patients with AD, whose diagnosis was supported by NDD findings (sAPP{alpha}: cutoff, 117.4 ng ml(-1), sensitivity, 68%, specificity, 85%, P<0.001; sAPP{beta}: cutoff, 181.8 ng ml(-1), sensitivity, 75%, specificity, 85%, P<0.001), from the patients clinically assessed as having other dementias and supported by NDD untypical for AD. We conclude sAPP{alpha} and sAPP{beta} might be regarded as novel promising biomarkers supporting the clinical diagnosis of AD