1,572 research outputs found

    Asynchronous functional reactive programming for GUIs

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    Can the internet reduce the loneliness of 50+ living alone?

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    Published online: 12 May 2020Living alone has been indicated as a key variable to explain loneliness in older adults. In contemporary society, where technology has become one of the main means of communication and personal interaction, has the internet influenced the relationship between living alone and loneliness? This paper aims to answer this research question by using a sample of 64,297 individuals who were surveyed in SHARE project wave 6 – in European countries with different welfare regimes (Portugal, Greece, Italy and Spain, Denmark, Sweden, Austria, Belgium, France, Germany, Switzerland, Luxemburg, Poland, Czech Republic; Slovenia, Estonia, and Croatia). The results of the regression analysis evidence the moderating role of the internet on the relationship between living alone and feelings of loneliness in individuals aged 50 and over, so that the impact of living alone on loneliness is diminished for internet users as compared to their peers who do not use the internet. The results therefore reinforce the importance of policies aimed at fostering e-inclusion as a way of reducing the loneliness of older adultsThis work was supported by European Commission; Fundação para a Ciência e a Tecnologia; U.S National Institute on Aging; Fundação Calouste Gulbenkian; German Ministry of Education and Researc

    Ultrastructural and functional fate of recycled vesicles in hippocampal synapses

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    Efficient recycling of synaptic vesicles is thought to be critical for sustained information transfer at central terminals. However, the specific contribution that retrieved vesicles make to future transmission events remains unclear. Here we exploit fluorescence and time-stamped electron microscopy to track the functional and positional fate of vesicles endocytosed after readily releasable pool (RRP) stimulation in rat hippocampal synapses. We show that most vesicles are recovered near the active zone but subsequently take up random positions in the cluster, without preferential bias for future use. These vesicles non-selectively queue, advancing towards the release site with further stimulation in an actin-dependent manner. Nonetheless, the small subset of vesicles retrieved recently in the stimulus train persist nearer the active zone and exhibit more privileged use in the next RRP. Our findings reveal heterogeneity in vesicle fate based on nanoscale position and timing rules, providing new insights into the origins of future pool constitution

    Single electron yields from semileptonic charm and bottom hadron decays in Au++Au collisions at sNN=200\sqrt{s_{NN}}=200 GeV

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    The PHENIX Collaboration at the Relativistic Heavy Ion Collider has measured open heavy-flavor production in minimum bias Au++Au collisions at sNN=200\sqrt{s_{_{NN}}}=200 GeV via the yields of electrons from semileptonic decays of charm and bottom hadrons. Previous heavy-flavor electron measurements indicated substantial modification in the momentum distribution of the parent heavy quarks due to the quark-gluon plasma created in these collisions. For the first time, using the PHENIX silicon vertex detector to measure precision displaced tracking, the relative contributions from charm and bottom hadrons to these electrons as a function of transverse momentum are measured in Au++Au collisions. We compare the fraction of electrons from bottom hadrons to previously published results extracted from electron-hadron correlations in pp++pp collisions at sNN=200\sqrt{s_{_{NN}}}=200 GeV and find the fractions to be similar within the large uncertainties on both measurements for pT>4p_T>4 GeV/cc. We use the bottom electron fractions in Au++Au and pp++pp along with the previously measured heavy flavor electron RAAR_{AA} to calculate the RAAR_{AA} for electrons from charm and bottom hadron decays separately. We find that electrons from bottom hadron decays are less suppressed than those from charm for the region 3<pT<43<p_T<4 GeV/cc.Comment: 432 authors, 33 pages, 23 figures, 2 tables, 2011 data. v2 is version accepted for publication by Phys. Rev. C. Plain text data tables for the points plotted in figures for this and previous PHENIX publications are (or will be) publicly available at http://www.phenix.bnl.gov/papers.htm

    Inclusive cross section and double-helicity asymmetry for π0\pi^{0} production at midrapidity in pp++pp collisions at s=510\sqrt{s}=510 GeV

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    PHENIX measurements are presented for the cross section and double-helicity asymmetry (ALLA_{LL}) in inclusive π0\pi^0 production at midrapidity from pp++pp collisions at s=510\sqrt{s}=510~GeV from data taken in 2012 and 2013 at the Relativistic Heavy Ion Collider. The next-to-leading-order perturbative-quantum-chromodynamics theory calculation is in excellent agreement with the presented cross section results. The calculation utilized parton-to-pion fragmentation functions from the recent DSS14 global analysis, which prefer a smaller gluon-to-pion fragmentation function. The π0ALL\pi^{0}A_{LL} results follow an increasingly positive asymmetry trend with pTp_T and s\sqrt{s} with respect to the predictions and are in excellent agreement with the latest global analysis results. This analysis incorporated earlier results on π0\pi^0 and jet ALLA_{LL}, and suggested a positive contribution of gluon polarization to the spin of the proton ΔG\Delta G for the gluon momentum fraction range x>0.05x>0.05. The data presented here extend to a currently unexplored region, down to x0.01x\sim0.01, and thus provide additional constraints on the value of ΔG\Delta G. The results confirm the evidence for nonzero ΔG\Delta G using a different production channel in a complementary kinematic region.Comment: 413 authors, 8 pages, 4 figures. v2 is version accepted as PRD Rapid Communication. Plain text data tables for the points plotted in figures for this and previous PHENIX publications are (or will be) publicly available at http://www.phenix.bnl.gov/papers.htm

    Nuclear matter effects on J/ψJ/\psi production in asymmetric Cu+Au collisions at sNN\sqrt{s_{_{NN}}} = 200 GeV

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    We report on J/ψJ/\psi production from asymmetric Cu+Au heavy-ion collisions at sNN\sqrt{s_{_{NN}}}=200 GeV at the Relativistic Heavy Ion Collider at both forward (Cu-going direction) and backward (Au-going direction) rapidities. The nuclear modification of J/ψJ/\psi yields in Cu++Au collisions in the Au-going direction is found to be comparable to that in Au++Au collisions when plotted as a function of the number of participating nucleons. In the Cu-going direction, J/ψJ/\psi production shows a stronger suppression. This difference is comparable in magnitude and has the same sign as the difference expected from shadowing effects due to stronger low-xx gluon suppression in the larger Au nucleus. The relative suppression is opposite to that expected from hot nuclear matter dissociation, since a higher energy density is expected in the Au-going direction.Comment: 349 authors, 10 pages, 4 figures, and 4 tables. Submitted to Phys. Rev. C. For v2, fixed LaTeX error in 3rd-to-last sentence. Plain text data tables for the points plotted in figures for this and previous PHENIX publications are (or will be) publicly available at http://www.phenix.bnl.gov/papers.htm

    Transverse energy production and charged-particle multiplicity at midrapidity in various systems from sNN=7.7\sqrt{s_{NN}}=7.7 to 200 GeV

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    Measurements of midrapidity charged particle multiplicity distributions, dNch/dηdN_{\rm ch}/d\eta, and midrapidity transverse-energy distributions, dET/dηdE_T/d\eta, are presented for a variety of collision systems and energies. Included are distributions for Au++Au collisions at sNN=200\sqrt{s_{_{NN}}}=200, 130, 62.4, 39, 27, 19.6, 14.5, and 7.7 GeV, Cu++Cu collisions at sNN=200\sqrt{s_{_{NN}}}=200 and 62.4 GeV, Cu++Au collisions at sNN=200\sqrt{s_{_{NN}}}=200 GeV, U++U collisions at sNN=193\sqrt{s_{_{NN}}}=193 GeV, dd++Au collisions at sNN=200\sqrt{s_{_{NN}}}=200 GeV, 3^{3}He++Au collisions at sNN=200\sqrt{s_{_{NN}}}=200 GeV, and pp++pp collisions at sNN=200\sqrt{s_{_{NN}}}=200 GeV. Centrality-dependent distributions at midrapidity are presented in terms of the number of nucleon participants, NpartN_{\rm part}, and the number of constituent quark participants, NqpN_{q{\rm p}}. For all AA++AA collisions down to sNN=7.7\sqrt{s_{_{NN}}}=7.7 GeV, it is observed that the midrapidity data are better described by scaling with NqpN_{q{\rm p}} than scaling with NpartN_{\rm part}. Also presented are estimates of the Bjorken energy density, εBJ\varepsilon_{\rm BJ}, and the ratio of dET/dηdE_T/d\eta to dNch/dηdN_{\rm ch}/d\eta, the latter of which is seen to be constant as a function of centrality for all systems.Comment: 706 authors, 32 pages, 20 figures, 34 tables, 2004, 2005, 2008, 2010, 2011, and 2012 data. v2 is version accepted for publication in Phys. Rev.
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