1 research outputs found
EVALUATION OF THE CHITOSAN-COATING EFFECTIVENESS ON A DENTAL TITANIUM ALLOY IN TERMS OF MICROBIAL AND FIBROBLASTIC ATTACHMENT AND THE EFFECT OF AGING
The aim of this study was to obtain a biocompatible and antimicrobial
implant surface by coating Ti6Al4V with chitosan which can be used to
create a smooth transmucosal region for a faster and better wound
healing and an increased bioactivity. Ti6Al4V plates were first abraded
and ultrasonically cleaned and then coated with chitosan. In order to
simulate the conditions of an oral environment, a group of coated plates
were treated in a thermocycle apparatus. The coatings were evaluated
with SEM, EDS, XRD and FTIR spectroscopy. The fibroblastic cell behavior
was determined using HGF-1 cells. P. gingivalis was used to assess the
effectiveness of chitosan as an antimicrobial coating.
It can be said that the Ti6Al4V plates were successfully coated with
chitosan, indicated by the presence of the C, H and O elements in the
EDS results. There were no significant differences between the XRD
patterns of the coated and uncoated plates; however, the characteristic
bands of chitosan were observed in the FTIR patterns of both the coated
and aged samples. The fibroblast-cell attachment and proliferation were
enhanced while the bacterial proliferation was inhibited by the chitosan
coating. Chitosan was shown to be a biologically useful material that
can be used as the coating material for transmucosal regions of dental
implants