Rhinitis in the geriatric population

The current geriatric population in the United States accounts for approximately 12% of the total population and is projected to reach nearly 20% (71.5 million people) by 2030[1]. With this expansion of the number of older adults, physicians will face the common complaint of rhinitis with increasing frequency. Nasal symptoms pose a significant burden on the health of older people and require attention to improve quality of life. Several mechanisms likely underlie the pathogenesis of rhinitis in these patients, including inflammatory conditions and the influence of aging on nasal physiology, with the potential for interaction between the two. Various treatments have been proposed to manage this condition; however, more work is needed to enhance our understanding of the pathophysiology of the various forms of geriatric rhinitis and to develop more effective therapies for this important patient population

Intranasal Corticosteroid Theraphy in Idiopathic Rhinitis: a Comparative Study with Allergic Rhinitis

American-Academy-of-Allergy-Asthma-and-Immunology Annual Meeting -- MAR 18-22, 2011 -- San Francisco, CAWOS: 000295846400777…Amer Acad Allergy Asthma & Immuno

Evaluation of IgE test results in clinical practice

Meeting of the European-Academy-of-Allergy-and-Clinical-Immunology -- JUN 11-15, 2016 -- Vienna, AUSTRIAKalpaklioglu, A. Fusun/0000-0002-6548-6932WOS: 000383679802203…European Acad Allergy & Clin Immuno

Efficacy and safety of H1-antihistamines: An update

PubMed: 23173575H1-antihistamines are inverse agonists that combine with and stabilize inactive conformation of H1-receptors. Thus they interfere with actions of histamine at H1-receptors. They are widely used for treatment of allergic rhinitis, allergic conjunctivitis, urticaria, coughs, colds and insomnia. H1-antihistamines are classified as older 'first generation' and newer 'second generation'. First generation H1-antihistamines have poor receptor H1-receptor selectivity, and cross blood-brain-barrier. They have a lot of adverse events such as anti-muscarinic, anti-?-adrenergic, anti-serotonin, and sedative effects. In contrast, second generation H1-antihistamines were highly selective for the histamine H1-receptor, do not cross the blood brain barrier, and have minimal adverse events. The risks of first-generation H1-antihistamines have been clearly underestimated, particularly when purchased as nonprescribed over the counter medications by public. This review summarizes curent literature to evaluate antihistamines including their mechanism, indications and side-effects. © 2012 Bentham Science Publishers

Correlation of fractional exhaled nitric oxide, nasal nitric oxide and atopic status: a cross-sectional study in allergic rhinitis

Congress of the European-Academy-of-Allergy-and-Clinical-Immunology -- JUN 06-10, 2015 -- Barcelona, SPAINKalpaklioglu, A. Fusun/0000-0002-6548-6932WOS: 000369950702403…European Acad Allergy & Clin Immuno

Is CRP a useful marker for inflammation in different forms of rhinitis?

63rd Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology -- FEB 23-27, 2007 -- San Diego, CAWOS: 000251460401556…Amer Acad Allergy, Asthma & Immuno