Unidirectional Lasing Emerging from Frozen Light in Non-Reciprocal Cavities

We introduce a class of unidirectional lasing modes associated with the frozen mode regime of non-reciprocal slow-wave structures. Such asymmetric modes can only exist in cavities with broken time-reversal and space inversion symmetries. Their lasing frequency coincides with a spectral stationary inflection point of the underlying passive structure and is virtually independent of its size. These unidirectional lasers can be indispensable components of photonic integrated circuitry.Comment: 5 pages, 3 figure

Does time equal vision in the acute treatment of a cohort of AQP4 and MOG optic neuritis?

Objective To investigate whether visual disability which is known to accumulate by poor recovery from optic neuritis (ON) attacks can be lessened by early treatment, we investigated whether the time from symptom onset to high-dose IV methylprednisolone (IVMP) affected visual recovery. Methods: A retrospective study was performed in a consecutive cohort of patients following their first aquaporin-4 (AQP4)-IgG or myelin oligodendrocyte glycoprotein (MOG)-IgG-ON. Best-corrected visual acuity (BCVA) in ON eyes at 3 months (BCVA3mo) was correlated with time to IVMP (days). In cases of bilateral ON, 1 eye was randomly selected. Results: A total of 29 of 37 patients had ON (27 AQP4-seropositive neuromyelitis optica spectrum disorder [NMOSD] and 9 MOG-IgG-ON), 2 of whom refused treatment. Of the 27 patients included, 10 presented later than 7 days from onset. The median BCVA3mo of patients treated >7 days was 20/100 (interquartile range 20/100–20/200). Patients treated >7 days had an OR of 5.50 (95% CI 0.88–34.46, p = 0.051) of failure to regain 0.0 logMAR vision (20/20) and an OR of 10.0 (95% CI 1.39–71.9) of failure to regain 0.2 logMAR vision (20/30) (p = 0.01) compared with patients treated within 7 days. ROC analysis revealed that the optimal criterion of delay in IVMP initiation was ≤4 days, with a sensitivity and specificity of 71.4% and 76.9%, respectively. Conclusions: In this retrospective study of ON with AQP4 and MOG-IgG, even a 7-day delay in IVMP initiation was detrimental to vision. These results highlight the importance of early treatment for the long-term visual recovery in this group of patients. A prospective, multicenter study of the effects of timing of IVMP is currently underway. Classification of evidence: This study provides Class IV evidence that hyperacute treatment of AQP4 and MOG-ON with IVMP increases the chance for good visual recovery (20/20 vision) and that even a greater than 7-day delay in treatment is associated with a higher risk for poor visual recovery

Intracranial internal carotid aneurysm causing diplopia

Internal carotid intracranial aneurysms are a relatively rare form of intracranial aneurysm that presents with diplopia, retro-orbital pain and unilateral headaches. The symptoms are progressive and the diagnosis should be considered in a patient presenting with these complaints. Underlying hypertension and advanced age are specific risk factors

CORROSION STUDIES FOR A FUSED SALT-LIQUID METAL EXTRACTION PROCESS FOR THE LIQUID METAL FUEL REACTOR

Corrosion screening tests were carried out on potential materials of construction for use in a fused salt-liquid metal extraction process plant. The corrodents of interest were NaCl--KCl-- MgCl/sub 2/ eutectic, LiCl--KCl eutectic, Bi-- U fuel, and BiCl/sub 3/, either separately or in various combinations. Screening tests to determine the resistance of a wide range of commercial alloys to the corrodents were performed in static and tilting-furnace capsules. Some ceramic materials were tested in static capsules. Largerscale tests of metallic materials were conducted in thermal convection loops and in a forced circulation loop. Some of the tests were conducted isothermally at 500 deg C, and others were performed under 40 to 50 deg C temperature differences at roughly the same teinperature level. On the basis of metallographic examination of exposed test tabs and chemical analyses of corrodents, it was found that the binary and ternary eutectics by themselves produced little attack on any of the materials tested. A wide variety of materials including 1020 mild steel, 2 1/4 Cr--1 Mo alloy steel, types 304 (ELC), 310, 316, 347, 430, and 446 stainless steel, 16-1 Croloy, Inconel, Hastelloy C, Inor-8, Mo, and Ta is, therefore, available for further study. Corrosion by the ternary salt-fuel system was characteristic of that produced by the fuel alone. Alloys such as 1020 mild steel, and 1 1/4 Cr--1/ 2 Mo, and 2 1/4 Cr--1 Mo alloy steel, which are resistant to fuel, would be likely choices at present for container materials. BiCl/sub 3/ produced extensive attack on ternary salt-fuel containers when the fuel contained insufficient concentrations of oxidizable solutes. Au and Al/sub 2/O/sub 3/ were the only materials not attacked by BiCl/sub 3/ in ternary salt alone. (auth

Recurrent myositis triggered by infections: a case report

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