Renal failure due to renal vein thrombosis in a fetus with growth restriction and thrombophilia

We report a case of renal vein thrombosis diagnosed at 27 weeks of gestation in a dichorionic twin pregnancy. The left kidney of one fetus was hyperechoic and enlarged with echoic streaks following the direction of interlobular veins and the loss of corticomedullary differentiation. In the following weeks, left kidney became smaller and echoic, and Doppler examination showed no flow in both artery and vein. The right kidney had totally normal appearance in the beginning, but it became enlarged and hyperechoic, and progressed into a small echoic kidney with no flow in artery and vein. In the postnatal ultrasound examination, both kidneys appeared hyperechoic with no vascularization in the hilum region. There was thrombosis in arteries and veins of both kidneys, as well as in the inferior vena cava. The investigation for thrombophilia resulted with the combined presence of heterozygote mutation in factor V Leiden and prothrombin 20210 genes

Heart failure caused by thyrotoxicosis in pregnancy-case report.

Purpose of Investigation: To emphasize the importance of untreated thyrotoxicosis in pregnancy. When left untreated, severe maternal, fetal and even neonatal adverse outcomes such as preeclampsia, premature labor, low birthweight infants and increased perinatal mortality are prone to complicate the pregnancy

Fetal Nasal Bone Hypoplasia in the Second Trimester: Comparison of Diagnostic Methods for Predicting Trisomy 21 (Down Syndrome)

Purpose. The aim of this prospective observational study was to identify the best method for use in diagnosing fetal nasal bone (NB) hypoplasia in the second trimester as a means of predicting trisomy 21 (Down syndrome)