10 research outputs found
The mole theory: primary function of melanocytes and melanin may be antimicrobial defense and immunomodulation (not solar protection)
Can the brain inhibit inflammation generated in the skin? The lesson of alpha-melanocyte-stimulating hormone
Effect of Alpha-Melanocyte-Stimulating Hormone on Interleukin 8 and Monocyte Chemotactic Protein 1 Expression in a Human Retinal Pigment Epithelial Cell Line
Factors associated with the risk of gingival disease in patients with rheumatoid arthritis
Alpha-Melanocyte Stimulating Hormone Protects against Cytokine-Induced Barrier Damage in Caco-2 Intestinal Epithelial Monolayers
Beneficial Effect of Covalently Grafted alpha-MSH on Endothelial Release of Inflammatory Mediators for Applications in Implantable Devices
Intravascular devices for continuous glucose monitoring are promising tools for the follow up and treatment of diabetic patients. Limiting the inflammatory response to the implanted devices in order to achieve better biocompatibility is a critical challenge. Herein we report on the production and the characterization of gold surfaces covalently derivatized with the peptide alpha-alpha-melanocyte stimulating hormone (alpha-MSH), with a quantifiable surface density. In vitro study demonstrated that the tethered alpha-MSH is able to decrease the expression of an inflammatory cytokine produced by endothelial cells