Evaluation of quality of life long-term respiratory and functional capacity after lung cancer surgery

Background: In this study we analyzed the relationship between quality of life and respiratory functions, functional capacity in patients who underwent pulmonary resection

SCLEROSING HEMANGIOMA OF THE LUNG CLINICOPATHOLOGIC AND IMMUNOHISTOCHEMICAL FEATURES

The aim of this study was to demonstrate the immunohistochemical profile of sclerosing hemangioma of the lung(SHL) as well as to analyse its clinicopathological features. Immunohistochemical analysis could be peroformed in 3 cases for antibodies against TTF-1, surfactant protein-B, NSE, Chromogranin A, synaptophsin, CD31, CD34, estrogen and progesteron receptors, cytokeratin 7 EMA, p53 and Ki-57. Positive immunoreactivity for EMA in both cells of SHL supports the epithelial origin of this tunor. Also, immunopositivity for TTF-1 (in both cells), cytokeratin 7 (in surface cells) and surfactant protein B (in surface cells) leads to pneumoctytic differentiation of tumor cells. Positivity for progersterone receptor antibody, although it was detected to be local, may be associated with the feamale predominancy of SHL. No evidence of a malignant phenotype was found by Ki-67 and p53 similar with literature. The results of our study were discussed and compared with literature

The diagnostic value of image guided percutaneous fine needle aspiration biopsy in equivocal mediastinal masses

Background and aims: The aim of this study was to assess the diagnostic value of image guided percutaneous fine needle aspiration (FNA) biopsy in equivocal mediastinal masses

Association Between Cytomorphological and Clinicopathological Features of Nonsmall Cell Lung Carcinoma

The most important prognostic factor for lung carcinoma which is one of the most common cancer types, is the stage of the tumor. In this study, we assessed the prognostic importance of cytomorphological features of lung carcinoma in transthoracic fine needle aspiration biopsies with their clinicopathologic correlation

Oxygen uptake kinetics during cardiopulmonary exercise testing and postoperative complications in patients with lung cancer

It is accepted that cardiopulmonary exercise testing is one of the most valuable parameters, especially peak oxygen uptake (VO(2)), for the evaluation of risk assessment in lung cancer surgery It therefore represents an attractive way of identifying a patient at high risk for postoperative complications. However, many patients do not achieve the maximal or predictive level during an incremental exercise testing. The purpose of the current investigation was to study the value of the oxygen uptake efficiency slope (OUES), which shows exercise capacity during submaximal testing, in predicting postoperative mortality in patients with bronchogenic carcinoma scheduled for lung resection. Forty-nine patients with bronchogenic carcinoma participated in studies with exercise tests as a preoperative evaluation. The peak VO(2) was calculated for each subject by averaging values obtained during the final 10 s of exercise. The following equation was used to determine OUES: VO(2)/log(10) VE. Peak VO(2) without postoperative complication was 22.8 +/- 3.3 ml/(kg min), however, peak VO(2) in patients with present complications was 19.1 +/- 4.2 ml/(kg min) (p = 0.001). In addition, although the mean OUES in patients with present complications was 11.1 +/- 1.2, the mean OUES in the absent group was 13.3 +/- 2.1 (p < 0.001). Although peak VO(2) is useful in evaluating selected patients with bronchogenic carcinoma, OUES is also a beneficial parameter and should be calculated and recorded with peak VO(2), a better predictor of poor surgical outcome than absolute values, and should be integrated into preoperative decision making. (C) 2009 Elsevier Ireland Ltd. All rights reserved