A COMPARATIVE STUDY ON EFFECTIVENESS OF VARIOUS MEDIUM OF ADVERTISEMENT IN PERAMBALUR DISTRICT

Advertising may be a sort of communication wont to encourage or persuade an audience to continue or to require some new action. Most commonly the desired result is to derive consumer with respect to a commercial offering. Advertisement covers all the activities connected with the giving of publicity regarding goods and services offered purchasable. Thus the aim of the study is to understand the effectiveness of various medium of advertising according to business needs & expectations to help business maximize their reach public acceptance, personalization, cost effectiveness by selecting the right medium to advertise.Advertisement plays an important role within the success of the business. There are various medium for advertising in today’s world. Each medium have its own merits and demerits to reach out to people. Here the study analyses which medium of advertisement is most effective for the popularity and growth of a business..Medium ormedia selection is a unique decision to be made by the advertiser. KEYWORDS: Advertisement, Communication, Publicity, Commercial, Medium, Decision

Virtues in Purananuru by Auvaiyar

If a man has good moral behavior then he must have been trained well by the elders. The virtues given by Auvaiyar in ‘Purananuru’ are to be followed by others to led a good life. Virtues among the people must be a natural outcome. When a person is hungry, he should be given food by the others. Giving food to others and satisfying a person’s hunger is a kind of virtue. Virtue is the primary source of all human needs. Auvaiyar points out that one who have good thoughts and moral behavior will get plenty of goodness. Similarly, if the king of a country decides to help others, he will come forward to help no matter time or situation it is. The king thinks giving food and gifts to soldiers is the best virtue. At present people are selfish, they earn and spent it for themselves but the kings of Sangam period helped others by giving what they had. They are happy to help the needy. One should help others when they are in dangerous situation. The person who received the help will not forget it as long as he lives, charity is a gift, the land of the virtuous people will always be rich, king’s helping mentality and the nature of helping the needy are discussed well in this article

Application of Qualitative Methods in Health Research: An Overview

Qualitative research is type of formative research that includes specialized techniques for obtaining in-depth responses about what people think and how they feel. It is seen as the research that seeks answer to the questions in the real world. Qualitative researchers gather what they see, hear, read from people and places, from events and activities, with the purpose to learn about the community and to generate new understanding that can be used by the social world. Qualitative research have often been conducted to answer the question “why” rather than “what”. A purpose of qualitative research is the construction of new understanding. Here, we present an overview of application of qualitative methods in health research. We have discussed here the different types of qualitative methods and how we and others have used them in different settings/scenarios; sample size and sampling techniques; analysis of qualitative data; validity in qualitative research; and ethical issues

Molecular mechanisms involved in the generation of calcium signals In insulin secreting cells.

Intracellular Ca 2+ regulates diverse cellular functions in almost all the cells. In the pancreatic ß-cells, Ca 2+ signals are critical for insulin secretion. An increase in the cytoplasmic free Ca 2+ concentration ([Ca 2+ ]i) triggers insulin secretion. Multiple mechanisms increase the [Ca 2+ ]i in the ß-cells, and in this respect depolarization of the plasma membrane and consequent Ca 2+ entry through the voltage-gated Ca 2+ channels is particularly important. For depolarization of ß-cells the closure of KATP channels is essential. In addition, cation channels belonging to Transient Receptor Potential (TRP) family are thought to play important roles in causing depolarization. Previous studies have reported that the Transient Receptor Potential Melastatin-like subtype 5 (TRPM5) channel, a Ca 2+ activated monovalent cation channel, is involved in the stimulus-secretion coupling in the mouse ß-cells. We aimed to study the role of the TRPM5 channel in regulating insulin secretion, and [Ca 2+ ]i in the rat ß-cells. Another focus of this thesis was to evaluate a new human inluinoma cell line as a model for studying Ca 2+ signaling in the ß-cells. Recently a genetically engineered human insulinoma cell line (EndoC-BH1) has been developed. We studied Ca 2+ signaling in the EndoC-BH1 cells, in an attempt to assess whether these cells could be used as a model for this purpose. For inhibiting the TRPM5 channels we used triphenyl phosphine oxide (TPPO), a selective and potent pharmacological inhibitor of the channel. We measured insulin secretion from the islets from Sprague-Dawley rats in batch incubations. For measuring [Ca 2+ ]i from single rat ß-cells and EndoC-BH1 cells, we used fura-2 based ratiometric microfluorometry. We found that TPPO did not inhibit insulin secretion triggered by KCl, or fructose but it significantly reduced insulin secretion in response to glucose, Larginine, and GLP-1. It also significantly inhibited the KATP channel-independent insulin secretion by glucose. TPPO significantly inhibited the [Ca 2+ ]i increase in response to L-arginine. It also inhibited the [Ca 2+ ]i increase triggered by glucose in a KATP channel independent mechanism. However, TPPO did not alter the [Ca 2+ ]i response triggered by KCl, fructose, glucose and GLP-1. We stimulated the EndoC-BH1 cells with gluocse, GLP-1, KCl, carbachol, Larginine, and tolbutamide. These agents that are known to increase [Ca 2+ ]i in the primary ß-cells also increased [Ca 2+ ]i in the these human insulinoma cells. Moreover, we found that GLP-1 was essential for eliciting Ca 2+ response in the EndoC-BH1 cells upon stimulation by tolbutamide and glucose. We conclude that in the rat islets, TRPM5 plays an important role in mediating insulin secretion by glucose, and L-arginine, and in potentiating the glucoseinduced insulin secretion by GLP-1. We also conclude that the EndoC-BH1cells responds by [Ca 2+ ]i increase upon stimulation by several well-known agonists

A STUDY ON EMPLOYEE RETENTION WITH SPECIAL REFERENCE CHETTINAD CEMENT ARIYALUR

The research titled on “A Study on employee retention strategies with special reference chettinad cement ariyalur limited” Ariyalur was conducted. Employee retention is the systematic effort to retain the current employees by providing best policies and to recognize various expectations of the employees. The challenge is not only to attract the talented employees and to retain them. The objective of the study is to analyze the organizational factors influencing the employee retention and to find individual factors leading employees to leave the organization and to examine the necessary conditions to retain the employees. The study has done through descriptive research method and the collection of primary data has done through single cluster sampling method under probability sampling method. The research design followed in this study is descriptive research. Questionnaire is used to collect primary data and conceptual review is used for secondary data collection through books, websites. From the study, the findings show that the respondents are satisfied with compensation benefits & working environment, the employees feel that their work load is high. The company can implement better working environment to the employees; they can provide proper job rotation to motivate them. Provide flexible work schedule to the employees

A parameter uniform fitted mesh method for a weakly coupled system of two singularly perturbed convection-diffusion equations

In this paper, a boundary value problem for a singularly perturbed linear system of two second order ordinary differential equations of convection- diffusion type is considered on the interval [0, 1]. The components of the solution of this system exhibit boundary layers at 0. A numerical method composed of an upwind finite difference scheme applied on a piecewise uniform Shishkin mesh is suggested to solve the problem. The method is proved to be first order convergent in the maximum norm uniformly in the perturbation parameters. Numerical examples are provided in support of the theory

A Case Study on Settlement of Oil Storage Tank Foundations

Foundations of 8 Steel Oil storage tanks and two fire water tanks were proportioned limiting total settlement to 100 mm. The soil at the site consists of alternating layers of cohesive and cohesionless soils. Settlement estimates were based on currently available methods with suitable modifications to the situation met with. The tanks were load tested (Hydrotest) and settlements observed at nine locations along the periphery on tank shell base. These observed settlements are compared with the estimated values

Stupendous Nanomaterials: Carbon Nanotubes Synthesis, Characterization, and Applications

Carbon nanotubes are promising to revolutionize several fields in material science and are suggested to open the way into nanotechnology. These circular rod-shaped carbon nanostructures have novel characteristics that lead them to being potentially beneficial in many applications in nanoscience and nanotechnology. Their precise surface place, stiffness, power, and resilience have brought about lots of exhilaration in various areas. Nanotubes are categorized as single-walled nanotubes, double-walled nanotubes, and multi-walled nanotube. Various techniques have been evolved to produce nanotubes in bulk, including of arc discharge, laser ablation, chemical vapor deposition, electrolysis, and ball milling. Since their first observation nearly 20 years ago by Iijima, carbon nanotubes have been the focus of considerable research. Numerous researchers have reported remarkable physical and chemical properties for this new form of advanced carbon nanomaterials. Carbon nanotubes offer tremendous opportunities for the development of new material systems. This paper provides a concise report on recent advances in carbon nanotubes and their potential applications

STABILITY-INDICATING REVERSED-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR ANALYZING INJECTION DOSAGE FORMULATION CONTAINING MEDROXYPROGESTERONE ACETATE AND ESTRADIOL CYPIONATE

Objective: Stability-indicating reversed-phase high-performance liquid chromatography method with photodiode array detection is described for the assay of medroxyprogesterone acetate (MDA) and estradiol cypionate (ECA) in bulk and injection dosage form. Methods: MDA and ECA were determined on a Cosmicsil (250 mm × 4 mm) C18, 5 μm analytical column using mobile phase of 0.1 M KH2PO4 and acetonitrile (65:35 v/v) supplied isocratically by a flow rate of 1 ml/min. During stress testing, the sample was subjected to stress with 0.1 N HCl, 0.1 N NaOH, 30% hydrogen peroxide, water, and 105°C in oven and sunlight. Method validation was done in accordance with international conference on harmonization. Results: The linear response was obtained over the concentration range from 2.5 to 7.5 μg/ml for ECA and 12.5 to 37.50 μg/ml for MDA. The recoveries of MDA and ECA were 99.31%–99.45% and 99.59%–99.79%, with relative standard deviation ranging from 0.021% to 0.217% and 0.027% to 0.187%, respectively. The limits of detection for MDA and ECA were 0.097 μg/ml and 0.042 μg/ml, respectively. The method was able to selectively quantitate MDA and ECA in the presence of the degradation products and, hence, can be considered as stability-indicating one. Proposed method was applied to the quantification of MDA and ECA in injection dosage form with good precision and accuracy. Conclusion: The method can be employed for routine and quality control analysis of MDA and ECA simultaneously

A comparative study on effectiveness of constraint induced movement therapy Versus conventional therapy in improving upper limb functional on patients with stroke.

INTRODUCTION : Constraint induece movement therapy is a rehabitation approach that is designed to reduce in capitating motor deficits of the upper limbs in patient after neurological injury and increase their functional independence. Conventional Therapy (CT) is a usual and customary care on improve the upper extremity function. AIM : The study is to find out whether there is any significant difference between constraint induced movement therapy versus conventional therapy in improving upper limb function on patients with stroke. METHODS : The study was experimental in nature. Twenty samples were selected using simple random sampling method and divided into two equal groups. 1. Experimental group – I, 2. Experimental group - II Pretest measurements of upper limb function were taken for both The groups using Fug1 – meyer scale. After the pretest, the experimental group – I received conventional therapy whereas experimental group II received constraint induced movement therapy for a period of 8 weeks. Post – test measurement where taken for both the experimental groups in a similar fashion as that of pretest assessment at the end of 8 weeks. RESULTS : The data was subjected to statistical analysis and the following results were obtained. Conventional therapy is significantly effective in improving upper limb function on patients with stroke. Constraint induced movement therapy is significantly effective in improving upper limb function on patients with stroke. Constraint induced movement therapy is significantly effective in improving upper limb function on patients with stroke. Constraint induced movement therapy is significantly effective in improving upper limb function than conventional therapy on patients with stroke. CONCLUSION ; The results of this study make us conclude that constraint include movement therapy is significantly effective in improving upper limb function than conventional therapy on patients with stroke