Outbreak of gastroenteritis caused by Yersinia pestis in Afghanistan.

Plague, which is most often caused by the bite of Yersinia pestis-infected fleas, is a rapidly progressing, serious disease that can be fatal without prompt antibiotic treatment. In late December 2007, an outbreak of acute gastroenteritis occurred in Nimroz Province of southern Afghanistan. Of the 83 probable cases of illness, 17 died (case fatality 20·5%). Being a case was associated with consumption or handling of camel meat (adjusted odds ratio 4·4, 95% confidence interval 2·2-8·8, P<0·001). Molecular testing of patient clinical samples and of tissue from the camel using PCR/electrospray ionization-mass spectrometry revealed DNA signatures consistent with Yersinia pestis. Confirmatory testing using real-time PCR and immunological seroconversion of one of the patients confirmed that the outbreak was caused by plague, with a rare gastrointestinal presentation. The study highlights the challenges of identifying infectious agents in low-resource settings; it is the first reported occurrence of plague in Afghanistan

Dependence and motivation to stop smoking as predictors of success of a quit attempt among smokers seeking help to quit.

INTRODUCTION: It is not known how well motivation to stop smoking predicts abstinence in a clinical sample relative to the most widely used measure of cigarette dependence. METHODS: A secondary analysis was conducted from a trial with 864 smokers making quit attempt. Fagerström Test of Cigarette Dependence (FTCD), Heaviness of Smoking Index (HSI), and motivation to stop smoking (composite of determination to quit and importance of quitting) were measured at baseline. Continuous smoking abstinence, validated by expired-air carbon monoxide, was assessed at 4weeks, 6months and 12months post-quit date. FTCD, HSI, non-HSI items in FTCD, and motivation were assessed as predictors of abstinence. RESULTS: In multiple-logistic regressions, controlling for age, gender and medication use, lower scores for FTCD, HSI and non-HSI all significantly predicted abstinence at all follow-ups, while motivation did not predict abstinence at any time. Likelihood ratio tests showed that the FTCD contributed most to the model at 4weeks and 6months; at 12months FTCD and non-HSI equally contributed most to the model. At 4weeks and 6months, predictions were improved by combining HSI and non-HSI components, compared with using these components alone. CONCLUSIONS: Cigarette dependence, measured by the FTCD, or by its HSI or non-HSI components, predicts both short-term and medium-term outcomes of attempts to stop smoking in treatment-seeking smokers involved in a clinical trial, whereas strength of motivation to stop predicts neither. Both the HSI and non-HSI components may be considered as briefer alternatives to the full FTCD

Effect of Magnetic Field on Torsional Waves in Non-Homogeneous Aeolotropic Tube

ABSTRACT The effect of magnetic field on torsional waves propagating in non-homogeneous viscoelastic cylindrically aeolotropic material is discussed. The elastic constants and non-homogeneity in viscoelastic medium in terms of density and elastic constant is taken. The frequency equations have been derived in the form of a determinant involving Bessel functions. Dispersion equation in each case has been derived and the graphs have been plotted showing the effect of variation of elastic constants and the presence of magnetic field. The obtained dispersion equations are in agreement with the classical result. The numerical calculations have been presented graphically by using MATLAB

Petrogenesis of plagiogranites in the Muslim Bagh Ophiolite, Pakistan: implications for the generation of Archaean continental crust

High-SiO2 rocks referred to as oceanic plagiogranites are common within the crustal sequences of ophiolites; however, their mode of petrogenesis is controversial with both late-stage fractional crystallization and partial melting models being proposed. Here, we present new whole-rock data from plagiogranitic dyke-like bodies and lenses from the lower and middle sections of the sheeted dyke complex of the Cretaceous Muslim Bagh Ophiolite, northwestern Pakistan. The plagiogranites have similar geochemical signatures that are inconsistent with them being the fractionation products of the mafic units of the Muslim Bagh Ophiolite. However, the plagiogranites all display very low TiO2 contents (<0.4 wt%), implying that they formed by partial melting of mafic rocks. Melt modelling of a crustal gabbro from the Muslim Bagh Ophiolite shows that the trace-element signature of the plagiogranites can be replicated by 5–10% melting of a crustal hornblende gabbro with amphibole as a residual phase, resulting in a concave-up middle rare Earth element pattern. Compositional similarities between the Muslim Bagh Ophiolite plagiogranites and Archaean TTG (trondhjemite–tonalite–granodiorite) has implications for the generation of juvenile Archaean continental crust. As the Muslim Bagh Ophiolite was derived in a supra-subduction zone, it is suggested that some Archaean TTG may have been derived from melting of mafic upper crust in early subduction-like settings. However, due to the small volume of Muslim Bagh Ophiolite plagiogranites, it is inferred that they can be instructive on the petrogenesis of some, but not all, Archaean TTG

Genetic distance and differences in happiness across nations: some preliminary evidence

Survey studies worldwide have revealed large differences in happiness, both within and across nations. Many of the within-nation differences have a genetic basis, as twin studies have shown. Is there also a genetic component in the large differences across nations? In this paper, we report an initial exploration of this question in 104 nations. We estimate the relative importance of the genetic component in a bilateral analysis, calculating the correlation between the distance in genetic profile and average happiness, measured as satisfaction with life-as-a-whole. In this analysis, genetic distance explains 8.4% of the variance in cross-national differences in happiness. However, after controlling for cultural, institutional, economic, and geographical differences between countries, the explained variance is significantly reduced. We conclude that the direct effect of genetic distance is probably small

EXPRESSION. OF HYBRID VIGOUR AND DOMINANCE IN INTERVARIETAL CROSSES OF COTTON

Level of hybrid vigour and dominance estimates for six quantitative and qualitative parameters were examined in intervarietal crosses of nine cultivars of cotton. Results demonstrated that the parents and their F 1 hybrids differed significantly (P &lt; 0.01) for all the traits studied indicating manifestation of heterosis for all the traits in at least one or more crosses. Highest average heterosis (32.41%), heterobeltiosis (16.37%) and dominance estimates (4.93) were found for number of bolls per plant. The extent of heterotic effects was appreciably influenced by the hybrid genotype, the direction of cross and the trait concerned. The cross Qalandri x Allepo-I may be selected as the superior hybrid combination which could be exploited in cotton breeding programme for developing new high yielding cotton varieties for commercial production

Effect of waste materials on acoustical properties of semi-dense asphalt mixtures

Among the urban societal burdens rolling noise generation from tire pavement interaction and urban waste stand apart. Many urban waste materials can be used in pavements with comparable mechanical performance. Noise-related pavement characteristics such as porosity, sound absorption and surface texture, were measured for semi-dense low noise pavement mixtures using urban waste materials namely: recycled concrete aggregates, crumb rubber, polyethylene terephthalate and polyethylene. The results show that the use of these materials is a viable sustainable option for low noise pavements, however that may affect the noise reduction properties. With values around 0.2 at 1000 Hz, the sound absorption of all the mixtures is relatively low and the use of mean profile depth (MPD) alone is not enough to characterize the noise reduction properties. Surface texture was altered in different degrees depending on the waste material used. The results presented can aid in policy pertaining to noise abatement and waste reduction

Implementation of Parallel K-Means Algorithm to Estimate Adhesion Failure in Warm Mix Asphalt

Warm Mix Asphalt (WMA) and Hot Mix Asphalt (HMA) are prepared at lower temperatures, making it more susceptible to moisture damage, which eventually leads to stripping due to the adhesion failure. Moreover, the assessment of the adhesion failure depends on the expertise of the investigator’s subjective visual assessment skills. Nowadays, image processing has gained popularity to address the inaccuracy of visual assessment. To attain high accuracy from image processing algorithms, the loss of pixels plays an essential role. In high-quality image samples, processing takes more execution time due to the greater resolution of the image. Therefore, the execution time of the image processing algorithm is also an essential aspect of quality. This manuscript proposes a parallel k means for image processing (PKIP) algorithm using multiprocessing and distributed computing to assess the adhesion failure in WMA and HMA samples subjected to three different moisture sensitivity tests (dry, one, and three freeze-thaw cycles) and fractured by indirect tensile test. For the proposed experiment, the number of clusters was chosen as ten (k = 10) based on k value and cost of k means function was computed to analyse the adhesion failure. The results showed that the PKIP algorithm decreases the execution time up to 30% to 46% if compared with the sequential k means algorithm when implemented using multiprocessing and distributed computing. In terms of results concerning adhesion failure, the WMA specimens subjected to a higher degree of moisture effect showed relatively lower adhesion failure compared to the Hot Mix Asphalt (HMA) samples when subjected to different levels of moisture sensitivity