7 research outputs found

    Engineered biosynthesis of milbemycins in the avermectin high-producing strain Streptomyces avermitilis

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    Additional file 3 : Figure S2. HPLC analysis of milbemycins produced from S. avermitilis mutant strains and authentic standard milbemycins

    Vulnerable maximizers: The role of decision difficulty

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    Adding to prior literature that has examined the relationship between maximization and dissatisfaction, the present research suggests that maximizers, as defined by the original maximization scale, are unhappier decision makers than satisficers because maximizers fail to adequately handle dissonant experiences. Throughout three studies that use different conceptualization and measurement of maximization, we show that maximizers are more vulnerable to negative feedback about one’s choice such that they decrease positivity toward the chosen option to a greater level than satisficers. However, this effect was mainly driven by the decision difficulty factor in the conceptualization of maximization. When decision difficulty was conceptualized as a defining component of maximization (Study 1 and 2), “maximizers” show greater positivity drop in the face of negative feedback. However, in the absence of a decision difficulty component, a recently proposed two-component model of maximization (the goal to get the best and search for alternatives; Cheek and Schwartz, 2016) did not play a significant role in predicting positivity drop, while perceived decision difficulty did (Study 3). Together our findings suggest that previously reported contradictory outcomes of maximization may be due to inconsistent conceptualization and measurement, especially treating decision difficulty as a defining component of maximization

    RRED: A Radiology Report Error Detector based on Deep Learning Framework

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    Radiology report is an official record of radiologists interpretation of patients radiographs and its a crucial component in the overall medical diagnostic process. However, it can contain various types of errors that can lead to inadequate treatment or delay in diagnosis. To address this problem, we propose a deep learning framework to detect errors in radiology reports. Specifically, our method detects errors between findings and conclusion of chest X-ray reports based on a supervised learning framework. To compensate for the lack of data availability of radiology reports with errors, we develop an error generator to systematically create artificial errors in existing reports. In addition, we introduce a Medical Knowledge-enhancing Pre-training to further utilize the knowledge of abbreviations and key phrases frequently used in the medical domain. We believe that this is the first work to propose a deep learning framework for detecting errors in radiology reports based on a rich contextual and medical understanding. Validation on our radiologist-synthesized dataset, based on MIMIC-CXR, shows 0.80 and 0.95 of the area under precision-recall curve (AUPRC) and the area under the ROC curve (AUROC) respectively, indicating that our framework can effectively detect errors in the real-world radiology reports.N
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