Inhibition of paracetamol-induced oxidative stress in rats by extracts of lemongrass (Cymbropogon citratus) and green tea (Camellia sinensis) in rats

The water extract of green tea and lemongrass were investigated for their antioxidant effects in Wistar albino rats. Control and Test groups of rats were administered with paracetamol (2 g/kg) on the 10th dayof the experiment while the test groups were pre-treated with 100 mg/kg body weight of green tea and lemongrass for 10 days. The effect of the extracts on serum levels of malondialdehyde, catalase activityand vitamin C were measured in paracetamol-induced hepatotoxicity in rats. Further, the effects of the extract on cholesterol and phospholipids were estimated. Cholesterol/phospholipids ratio was computed. The extracts of green tea and lemongrass produced significant (