1 research outputs found
Antibacterial and cytotoxic activities of <i style="">Spondias pinnata </i>(Linn. f.) Kurz fruit extract
265-267The
plant Spondias pinnata (Linn. f.) Kurz belonging to Anacardiaceae
family, is used as a medicinal agent in Bangladesh. In the present
investigation, attempt was undertaken to study the antibacterial potency and
cytotoxic activity of 80% ethanol extract of its fruit. The antibacterial
activity was performed by the disc diffusion method and cytotoxicity was
observed by brine shrimp lethality bioassay. The fruit extract exhibited mild
to potent antibacterial activity against some Gram-positive and Gram-negative
bacteria at a concentration of 500 µg/disc. Among
them Pseudomonas aeruginosa and Staphylococcus epidermidis shows promising result. The ethanolic extract revealed strong cytotoxicity having
LC50 of 2.12±0.09 µg/ml.</span