Hazard Ratios of Contact to a Psychiatric Hospital for Specific Psychiatric Diagnoses among Individuals with Non-Syndromic Oral Cleft Compared With the Matched Comparison Cohort.

<p>Hazard Ratios of Contact to a Psychiatric Hospital for Specific Psychiatric Diagnoses among Individuals with Non-Syndromic Oral Cleft Compared With the Matched Comparison Cohort.</p

Characteristics of Individuals with Non-Syndromic Oral Cleft and the Matched Comparison Cohort.

<p>Characteristics of Individuals with Non-Syndromic Oral Cleft and the Matched Comparison Cohort.</p

Inclusion Criteria for Individuals with Non-Syndromic Oral Cleft and Matched Comparison Cohort.

<p>Inclusion Criteria for Individuals with Non-Syndromic Oral Cleft and Matched Comparison Cohort.</p

Classification of Psychiatric Disorders According to ICD-10-DCR and equivalent ICD-8 Diagnoses.

<p>Classification of Psychiatric Disorders According to ICD-10-DCR and equivalent ICD-8 Diagnoses.</p

Cutoff values defining high-risk levels of biomarkers.

<p>a) Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults. Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001; 285: 2486–2497.</p><p>b) NHLBI Obesity Education Initiative Expert Panel on the Identification, Evaluation, and Treatment of Obesity in Adults (US). Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults—the evidence report. Obes Res 1998;6:51S-209S.</p><p>c) WHO. Waist circumference and waist-hip ratio: Report of a WHO expert consultation, Geneva 2011: World Health Organization.</p><p>d) Mancia G, Fagard R, Narkiewicz K, et al. ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 2013;34:2159–2219.</p><p>e) Rodbard H, Blonde L, Braithwaite S, Brett E, Cobin R, et al. American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the Management of Diabetes Mellitus. Endocrine Practice 2007; 13: 1–68.</p><p>f) Pearson TA, Mensah GA, Alexander RW, et al. Markers of Inflammation and Cardiovascular Disease: Application to Clinical and Public Health Practice: A Statement for Healthcare Professionals From the Centers for Disease Control and Prevention and the American Heart Association. Circulation 2003;107:499–511.</p><p>g) Defined by the highest quintile of the sex-specific distribution.</p><p>h) Prineas RJ, Crow RS, Zhang Z-M. The Minnesota Code Manual of Electrocardiographic Findings. London: Springer-Verlag London New York; 2010.</p><p>Cutoff values defining high-risk levels of biomarkers.</p

Association of poor self-rated health with biomarker levels in the total and sex-specific samples.

<p>a: Model 1 includes sex, age, and quadratic age; Model 2: Model 1 plus biomarker (each separately), smoking status, current alcohol consumption, and presence of alcohol problems in the past.</p><p>b: HDL—high density lipoproteins, Hb–hemoglobin, CRP—C-reactive protein, IL-6—interleukin-6, MI–myocardial infarction, Major Q-wave–Major Q-wave abnormalities with high MI probability, AF–atrial fibrillation or atrial flutter, LVH-ST—Left ventricular hypertrophy plus ST-T abnormalities, OR–odds ratio, CI–confidence interval.</p><p>Association of poor self-rated health with biomarker levels in the total and sex-specific samples.</p

Prevalence of high-risk levels of biomarkers.

<p>a: ASP–age-standardized prevalence (based on the standard European population), SE–standard error, HDL—high density lipoproteins, Hb–hemoglobin, CRP—C-reactive protein, IL-6—interleukin-6, MI–myocardial infarction, Major Q-wave–Major Q-wave abnormalities with high MI probability, AF–atrial fibrillation or atrial flutter, LVH-ST—Left ventricular hypertrophy plus ST-T abnormalities.</p><p>Prevalence of high-risk levels of biomarkers.</p

Descriptive statistics of poor physical functioning and poor self-rated health.

<p>a: SE—standard error, ASP–age–standardized prevalence</p><p>b: p–value for sex difference in the prevalence of poor physical functioning and poor self-rated health</p><p>Descriptive statistics of poor physical functioning and poor self-rated health.</p

Association of physical functioning with biomarker levels in total and sex-specific samples.

<p>a: Model 1 includes sex, age, and quadratic age; Model 2: Model 1 plus biomarker (each separately), smoking status, frequency of current alcohol consumption, and presence of alcohol problems in the past</p><p>b: HDL—high density lipoproteins, Hb–hemoglobin, CRP—C-reactive protein, IL-6—interleukin-6, MI–myocardial infarction, Major Q-wave–Major Q-wave abnormalities with high MI probability, AF–atrial fibrillation or atrial flutter, LVH-ST—Left ventricular hypertrophy plus ST-T abnormalities, OR–odds ratio, CI–confidence interval.</p><p>Association of physical functioning with biomarker levels in total and sex-specific samples.</p

Temporality and impact of morbidity in singletons diagnosed with hypothyroidism.

<p>a) Overall associations: number of individuals with a first time hit of the respective disease category.</p><p>b) P-value from overall associations.</p><p>c) Odds ratios before the diagnosis of hypothyroidism, adjusted for age and sex.</p><p>d) Hazard ratios after the diagnosis of hypothyroidism, adjusted for the Charlson score.</p><p>e) Dementia, gastric ulcer, liver disease, liver failure, hemiplegia, kidney disease, and AIDS Data given in bold represent significant findings.</p