10 research outputs found
Molecular Interactions between Prions as Seeds and Recombinant Prion Proteins as Substrates Resemble the Biological Interspecies Barrier In Vitro
- Author
- C Wong
- Claudine Mayer
- Detlev Riesner
- Dieter Willbold
- DL Vanik
- DW Colby
- DW Colby
- E Birkmann
- Eva Birkmann
- FE Cohen
- G Legname
- G Panza
- GA Wells
- Giannantonio Panza
- GJ Raymond
- GP Saborio
- I Mehlhorn
- IV Baskakov
- J Safar
- J Stohr
- Jan Stöhr
- JC Geoghegan
- JC Watts
- JD Harper
- JT Jarrett
- Jürgen Weiβ
- K Jansen
- KM Green
- KW Leffers
- L Li
- Lars Luers
- Luitgard Nagel-Steger
- M Eigen
- M Laurent
- NR Deleault
- OV Bocharova
- R Atarashi
- RH Kimberlin
- T Konold
- V Beringue
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2009
- Field of study
Prion diseases like Creutzfeldt-Jakob disease in humans, Scrapie in sheep or bovine spongiform encephalopathy are fatal neurodegenerative diseases, which can be of sporadic, genetic, or infectious origin. Prion diseases are transmissible between different species, however, with a variable species barrier. The key event of prion amplification is the conversion of the cellular isoform of the prion protein (PrPC) into the pathogenic isoform (PrPSc). We developed a sodiumdodecylsulfate-based PrP conversion system that induces amyloid fibril formation from soluble α-helical structured recombinant PrP (recPrP). This approach was extended applying pre-purified PrPSc as seeds which accelerate fibrillization of recPrP. In the present study we investigated the interspecies coherence of prion disease. Therefore we used PrPSc from different species like Syrian hamster, cattle, mouse and sheep and seeded fibrillization of recPrP from the same or other species to mimic in vitro the natural species barrier. We could show that the in vitro system of seeded fibrillization is in accordance with what is known from the naturally occurring species barriers
Cross Slip Viewed at the Nano- and Micrometer Scale
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2004
- Field of study
Time-of-flight magnetic resonance angiography in the follow-up of intracranial aneurysms treated with Guglielmi detachable coils
- Author
- 3rd Huston J
- A. M. van der Vliet
- AB Boulin
- AE Casasco
- AM Leffers
- C Cognard
- CG McDougall
- CP Derdeyn
- D Roy
- F Vinuela
- FG Shellock
- G Guglielmi
- G Guglielmi
- G Guglielmi
- G Schuierer
- H. E. Westerlaan
- J. D. M. Metzemaekers
- J. J. A. Mooij
- J. M. Hew
- JE Heiserman
- JG Rowe
- JH Gurian
- JKA Hope
- JR Waugh
- JS Ross
- JV Byrne
- JV Byrne
- JV Byrne
- KW Stock
- L Brunereau
- L. C. Meiners
- M. Oudkerk
- N Anzalone
- NC Todd
- NG Warnock
- S Matsubara
- S Mullan
- S Mullan
- S Tateshima
- SW Atlas
- T Horikoshi
- T Lin
- TF Massoud
- TJ Hodgson
- TW Malisch
- U Grzyska
- VB Graves
- VJ Kähära
- W Weber
- WM Adams
- Y Korogi
- Y Korogi
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The ultrastructure of infectious L-type bovine spongiform encephalopathy prions constrains molecular models
- Author
- A Aguzzi
- A Kraus
- A Senatore
- AG Biacabe
- AV Kajava
- B Caughey
- B Chesebro
- BR Groveman
- BW Caughey
- C Casalone
- C Govaerts
- C Terry
- C Terry
- CJ Silva
- DJ Levine
- E Vazquez-Fernandez
- EF Pettersen
- F Lopez Garcia
- F Wang
- G Spagnolli
- G Spagnolli
- GA Wells
- H Wille
- H Wille
- H Wille
- H Wille
- H Wille
- I Vanni
- IV Baskakov
- J Frank
- J Safar
- JG Jacobs
- JG Safar
- JM Flores-Fernández
- JP Glaves
- JR Requena
- JW Wilesmith
- KJ Knaus
- KW Leffers
- LQ Wang
- M MartÃn-Pastor
- M Ohi
- M van Heel
- M Zweckstetter
- MR Scott
- N Nathanson
- NJ Cobb
- R Morales
- R Riek
- S Dudas
- SB Prusiner
- SB Prusiner
- SJ Ludtke
- T Konold
- V Smirnovas
- VL Sim
- W Goldmann
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Seeded Fibrillation as Molecular Basis of the Species Barrier in Human Prion Diseases
- Author
- AF Hill
- AH Peden
- B Demeler
- CD Orru
- Detlev Riesner
- Dieter Willbold
- DW Colby
- E Birkmann
- E Birkmann
- ED Belay
- Eva Birkmann
- F Wang
- G Legname
- G Panza
- G Panza
- G Tamguney
- GJ Raymond
- GJ Raymond
- GP Saborio
- J Castilla
- J Castilla
- J Collinge
- J Collinge
- J Cuillé
- J Safar
- J Stohr
- Jan Stöhr
- JD Harper
- JW Ironside
- JW Wilesmith
- KM Green
- KW Leffers
- L Li
- Lars Luers
- Luitgard Nagel-Steger
- M Caramelli
- M Eigen
- MA Barria
- Mark D. Zabel
- Martin Wolff
- ME Bruce
- Michael Marius Wördehoff
- MK Sandberg
- MR Scott
- MW Miller
- N Hunter
- NR Deleault
- O Andreoletti
- Oliver Bannach
- P Brown
- Q Kong
- R Atarashi
- R Atarashi
- R Wilson
- RF Marsh
- RG Will
- RG Will
- RT Johnson
- S Mawhinney
- S Vascellari
- V Beringue
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Treatment of Intracranial Aneurysms: Clipping Versus Coiling
- Author
- A Campi
- A Keedy
- A Molyneux
- A Morita
- AJ Molyneux
- AJ Molyneux
- AM Leffers
- Ann Liu
- AP Lozier
- AS Pandey
- B Krischek
- BL Hoh
- BL Hoh
- C Raftopoulos
- CG Mcdougall
- CG McDougall
- CS Ogilvy
- D Fiorella
- D Krex
- D Tampieri
- DO Wiebers
- DO Wiebers
- DO Wiebers
- E Lusseveld
- EH Brilstra
- EJ Lee
- ET Chappell
- F Caranci
- F Proust
- FH Linn
- G Lanzino
- G Pradilla
- G Schuierer
- GJ Rinkel
- GJ Zipfel
- HA Deutschmann
- HH Weng
- J Hernesniemi
- J Menke
- J Raymond
- J Rinne
- JB Bederson
- JE Dion
- JE Heiserman
- JJ Connors 3rd
- JL Brisman
- JM Caplan
- JM Caplan
- JM Gelder van
- JM Wardlaw
- JR Waugh
- Judy Huang
- K Ohno
- K Tsutsumi
- KE Schwab
- KW Stock
- M Kangasniemi
- M Lehecka
- M Okahara
- M Piotin
- M Ryttlefors
- M Sonobe
- MF Berman
- MH Vlak
- MJ Harrison
- MJ Wermer
- MS Pearl
- MW Vernooij
- NG Warnock
- P Mitchell
- PM White
- PN Karamanakos
- PV Raja
- R Anxionnat
- R Gasparotti
- R Sellar
- R Vanninen
- RE Harbaugh
- RF Spetzler
- S Asari
- S Bracard
- S Dammert
- S Juvela
- S Juvela
- S Tanoue
- SC Johnston
- SC Johnston
- SC Johnston
- SM Raza
- T Koivisto
- T Koivisto
- Unruptured intracranial aneurysms--risk of rupture and risks of surgical intervention
- VL Chiang
- VS Alg
- W Brinjikji
- W Brinjikji
- WE Dandy
- WE Stehbens
- Y Cai
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Prognostic biomarkers in endometrial and ovarian carcinoma
- Author
- A Abe
- A Alkushi
- A Bali
- A Gan
- A Katagiri
- A Sorolla
- A Steinbakk
- A Yeramian
- AA Ahmed
- AJ Bock
- AM Gassel
- AS Felix
- B Clarke
- B Davidson
- B Lindahl
- BA Clarke
- Ben Davidson
- BT Hennessy
- C Bárcena
- C Kandoth
- C Krakstad
- C Li
- C Morrison
- C Palmieri
- C Tempfer
- CA Hamilton
- CA Liebscher
- Cancer Genome Atlas Research Network
- CB Bijen
- CB Gilks
- CY Hsu
- D Delair
- D Llobet
- D Llobet
- DA Garcia-Dios
- DE Pinke
- DJ Hetzel
- DS Tan
- E Birkeland
- E Kuhn
- E Ortega
- E Wik
- ES Ratner
- F Marmé
- F Meng
- F Yang
- G Bonatz
- G Bonatz
- G Liu
- GP Sfakianos
- H Tanabe
- HB Salvesen
- HB Salvesen
- HB Salvesen
- HT Stavnes
- I Diaz-Padilla
- I Shih
- I Sohn
- IB Engelsen
- IB Engelsen
- IB Engelsen
- IM Bachmann
- IM Stefansson
- IM Stefansson
- J Dupont
- J Huang
- J Huvila
- J Kang
- J PlanagumÃ
- J Prat
- J Prat
- JD Seidman
- JD Wright
- JE Allard
- JE Carser
- JE Spowart
- JI Weberpals
- JM Pijnenborg
- JM Pijnenborg
- JM Pijnenborg
- JM Rubatt
- JY Lee
- K Brusegard
- K Hoshimoto
- K Ito
- K Levan
- K Milne
- K Shoji
- KJ Dedes
- KL White
- KW Min
- L BergadÃ
- L Kleinberg
- L Yu
- LA Brown
- LC Britton
- LM Prentice
- M Karaayvaz
- M Köbel
- M Köbel
- M Mannelqvist
- M Mannelqvist
- M Pradhan
- M Santacana
- M Schwede
- M Yanokura
- MB Elstrand
- MB Elstrand
- MB Raeder
- MJ Callahan
- MK McConechy
- MM Woo
- MT Rahman
- N Kapucuoglu
- N Leffers
- N Leffers
- NG Ordóñez
- NW Hamel
- P Chaudhry
- P Graeff de
- P Mhawech-Fauceglia
- P Mhawech-Fauceglia
- P Mhawech-Fauceglia
- PA Konstantinopoulos
- PM O’Brien
- R Ali-Fehmi
- R Sabatier
- R Siegel
- RA Jong de
- RA Jong de
- RA Soslow
- RG Verhaak
- RJ Kurman
- RW Tothill
- S Aust
- S Banerjee
- S Bondong
- S Darb-Esfahani
- S Yamamoto
- S Yamamoto
- S Yamamoto
- SA Byron
- SF Lax
- SL Leen
- SP Tsofack
- SS Li
- T Hogberg
- T Susini
- TE Hetland
- TM Zaid
- TZ Tan
- V Jongen
- VH Jongen
- W Kildal
- W Sieh
- W Tian
- W Weichert
- WG McCluggage
- WT Hwang
- X Dolcet
- Xavier Matias-Guiu
- XB Trinh
- Y Kanamori
- Y Liu
- Y Yao
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
High-resolution structure of infectious prion protein: the final frontier
- Author
- A Aguzzi
- AA Serag
- AL Delez
- AM Deleault
- B Caughey
- B Caughey
- B Caughey
- B Chesebro
- B Frost
- B Schuler
- BC May
- BH Toyama
- BW Caughey
- C Govaerts
- C Meyerett
- C Soto
- C Soto
- C Soto
- C Soto
- C Wasmer
- CJ Sigurdson
- CL Wilder
- Claudio Soto
- D Peretz
- D Riesner
- D Westaway
- DA Kocisko
- DC Bolton
- DC Gajdusek
- DW Colby
- DW Colby
- ED Eanes
- F Chiti
- F Wang
- F Wang
- G Legname
- GP Saborio
- GS Baron
- GS Jackson
- GT Westermark
- H Büeler
- H Diringer
- H Wille
- H Wille
- IV Baskakov
- J Castilla
- J Castilla
- J Castilla
- J Collinge
- J Collinge
- J Collinge
- J Hope
- J Safar
- JC Geoghegan
- JI Ayers
- JI Kim
- JI Kim
- JR Piro
- JR Piro
- JR Silveira
- JS Griffith
- JT Jarrett
- K Abid
- KE Nazor
- KM Pan
- KW Leffers
- M Junker
- MA Baldwin
- MA Pastrana
- ML DeMarco
- MP McKinley
- MP McKinley
- N Makarava
- N Stahl
- NJ Cobb
- NJ Cobb
- NJ Cobb
- NR Deleault
- NR Deleault
- OV Bocharova
- P Aucouturier
- P Brundin
- P Parchi
- P Tixador
- PA Merz
- R Chiesa
- R Gabizon
- R Halfmann
- R Halfmann
- R Nelson
- R Nelson
- R Riek
- RA Bessen
- RA Williamson
- RB Wickner
- RG Will
- Rodrigo Diaz-Espinoza
- S Cronier
- S Supattapone
- S Supattapone
- SB Prusiner
- SM Uptain
- T Alper
- V Adler
- V Smirnovas
- VL Sim
- WK Surewicz
- WS Jackson
- Y Cordeiro
- Y Cordeiro
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Ovarian Cancer: Diagnostic, Biological and Prognostic Aspects
- Author
- Abe A
- Ahmed AA
- Aust S
- Banerjee S
- Beach A
- Bearfoot JL
- Bendoraite A
- Berek JS
- Bondong S
- Boyerinas B
- Bárcena C
- Caburet S
- Cancer Genome Atlas Research Network
- Carser JE
- Chao A
- Cho JA
- Clarke B
- Corney DC
- Davidson B
- Davidson B
- Davidson B
- de Graeff P
- Delair D
- Elstrand MB
- English DP
- Escrevente C
- Fang H
- Flavin R
- Fu X
- Gan A
- Gilbert L
- Gilks CB
- Heravi-Moussavi A
- Hetland TE
- Holman LL
- Hu X
- Hwang WT
- Kang J
- Karagiannis GS
- Katagiri A
- Kataoka F
- Kleinberg L
- Kobayashi M
- Konstantinopoulos PA
- Kuhn E
- Köbel M
- Köbel M
- Köbel M
- Laios A
- Leen SL
- Leffers N
- Li C
- Li J
- Liang B
- Liu Z
- Lu KH
- Marchini S
- Marmé F
- Marsh T
- McCann CK
- McCluggage WG
- Mhawech-Fauceglia P
- Milne K
- Min KW
- Mitamura T
- Mitra AK
- Morotti M
- Moyer VA
- Nik NN
- O'Brien PM
- Ordóñez NG
- Palmieri C
- Partridge EE
- Peng DX
- Peng P
- Permuth-Wey J
- Polanska UM
- Polytarchou C
- Prat J
- Qiu W
- Rahman MT
- Reade CJ
- Rubatt JM
- Ryland GL
- Sabatier R
- Schenberg T
- Schwede M
- Sfakianos GP
- Shih KK
- Siegel R
- Sieh W
- Slomski A
- Soslow RA
- Spowart JE
- Stavnes HT
- Sun C
- Tan DS
- Tan TZ
- Tanabe H
- Tang Z
- Tothill RW
- Trinh XB
- Tropé CG
- Tsofack SP
- Vaksman O
- Valadi H
- Vang S
- Vecchione A
- Verhaak RG
- Walters CL
- Wang S
- Wang S
- Weberpals JI
- Weissman SM
- White KL
- Wurz K
- Yamamoto S
- Yamamoto S
- Yang F
- Yeh YM
- Zaid TM
- Publication venue
- 'Future Medicine Ltd'
- Publication date
- Field of study
Schussverletzungen
- Author
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- A Fatteh
- A Fatteh
- A Goonetilleke
- A Goonetilleke
- A Gross
- A Illchmann-Christ
- A Isfort
- A Jason
- A Schöntag
- A Schöntag
- A Schöntag
- A Suneson
- A Suneson
- A Suneson
- A Werkgartner
- A Werkgartner
- A Yellin
- AB Zhuk
- AH Ross
- AJ Bentley
- AJ Chapman
- AJ Dziemian
- AJ Dziemian
- AJ Ritchie
- AM Jones
- AM Jones
- AN Black
- AR Copeland
- AR Josselson
- AS Soliman
- AW Carroll
- AW Wolf
- B Gerdin
- B Jacob
- B Janzon
- B Janzon
- B Janzon
- B Karger
- B Karger
- B Karger
- B Karger
- B Karger
- B Karger
- B Karger
- B Karger
- B Karger
- B Karger
- B Karger
- B Karger
- B Karger
- B Karger
- B Karger
- B Karger
- B Karger
- B Karger
- B Karger
- B Karger
- B Karger
- B Knight
- B Leffers
- B Madea
- B Madea
- B Mueller
- B Randall
- B Randall
- BD Ragsdale
- BD Ragsdale
- BD Ragsdale
- BD Ragsdale
- BD Ragsdale
- BD Ragsdale
- BG Stephens
- BL Petersen
- BN Mattoo
- BP Kneubuehl
- BP Kneubuehl
- BP Kneubuehl
- BP Kneubuehl
- BR Burnett
- BV Stromberg
- BW Given
- C Franz
- C Goroncy
- C Journee
- C Mallak
- C Schyma
- C Schyma
- C Schyma
- C Schyma
- C Schyma
- C Zietlow
- CA Balouris
- CA Nichols
- CA Nichols
- CE Peters
- CE Peters
- CE Peters
- CHM Choi
- CI Stone
- CI Stone
- CI Stone
- CJ Clemedson
- CJ Stahl
- CJ Stahl
- CM Herget
- Cranz C (1925/1926/1927) Lehrbuch der Ballistik Bd. I (1925),Bd. II
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- CS Petty
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- EN Harvey
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- EP Marshall
- ER Donoghue
- F Bakonyi
- F Hausbrandt
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- F Introna
- F Michelassi
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- P Shen
- P Zink
- P Zink
- PC Hartline
- PE Lantz
- PF Guerin
- PJ Cashman
- PJT Knudsen
- PJT Knudsen
- PJT Knudsen
- PJT Knudsen
- PJT Knudsen
- PJT Knudsen
- PL Morrow
- PSJ Ellis
- PT Orlowskil
- R Berlin
- R Berlin
- R Berlin
- R Berlin
- R Breitenecker
- R Breitenecker
- R Breitenecker
- R Cooper
- R Cornelis
- R Henn
- R Klaue
- R Lorenz
- R Miller
- R Nennnstiel
- R Nennstiel
- R Scott
- R Selway
- R Touquet
- RA Steindler
- RA Wascher
- RC Challener
- RC Harruff
- RC Menzies
- RE Gold
- RE Mittieman
- RF Bellamy
- RH Lewis
- RK Bentsen
- RL Rivers
- RL Singer
- RL Thompson
- RM Brissie
- RM Mayer
- Rommeney
- RT Sherman
- RU Krönlein
- S Basu
- S Berg
- S Berg
- S Berg
- S Cohle
- S Kellermann
- S Pollak
- S Pollak
- S Pollak
- S Pollak
- S Pollak
- S Pollak
- S Pollak
- S Pollak
- S Pollak
- S Pollak
- S Smith
- S Thoresen
- S Tikka
- S-O Baik
- SC Rose
- SE Conradi
- SJ Bond
- SJ Cina
- SP Avis
- SR Jones
- SR Jones
- SS Krishnan
- SYA Ragheb
- T Bhoopat
- T Karlsson
- T Karlsson
- T Kocher
- T Lochte
- T Schwär
- T Sigrist
- T Suwanjutha
- TA Gonzales
- TA Warlow
- TB Cole
- TM Canfield
- TO Marsh
- TW Burke
- TW Burke
- U Klages
- U Klages
- V Drake
- V Levy
- V Schmidt
- V Schneider
- VF Rowe
- VJ Rao
- VJ Rao
- VJM Dimaio
- VJM Dimaio
- VJM Dimaio
- VJM Dimaio
- VJM Dimaio
- VJM Dimaio
- VJM Dimaio
- VJM Dimaio
- VJM Dimaio
- VW Weedn
- W Ballhause
- W Boltz
- W Brüning
- W Dittmann
- W Eisenmenger
- W Harris
- W Heess
- W Holczabek
- W Janssen
- W Janssen
- W Janssen
- W Janssen
- W Janssen
- W Kanert
- W Kokinakis
- W Krauland
- W Krauland
- W Lampel
- W Lampel
- W Lampel
- W Marty
- W Marty
- W Marty
- W Nasilowski
- W Pflug
- W Pichler
- W Rabl
- W Rabl
- W Robens
- W Sattler
- W Schollmeyer
- W Schollmeyer
- W Tributsch
- W Weber
- W Weber
- W Weimann
- W Weimann
- W Weimann
- W Weimann
- WE Demuth Jr
- WJ Bruchey
- WP Sight
- WU Spitz
- WU Spitz
- XY Cheng
- ZG Wang
- ZG Wang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2004
- Field of study