A Femtosecond Neutron Source

The possibility to use the ultrashort ion bunches produced by circularly polarized laser pulses to drive a source of fusion neutrons with sub-optical cycle duration is discussed. A two-side irradiation of a thin foil deuterated target produces two countermoving ion bunches, whose collision leads to an ultrashort neutron burst. Using particle-in-cell simulations and analytical modeling, it is evaluated that, for intensities of a few $10^{19} W cm^{-2}$, more than $10^3$ neutrons per Joule may be produced within a time shorter than one femtosecond. Another scheme based on a layered deuterium-tritium target is outlined.Comment: 15 pages, 3 figure

Relationship between radiographic changes and symptoms or physical examination findings in subjects with symptomatic medial knee osteoarthritis: a three-year prospective study

<p>Abstract</p> <p>Background</p> <p>Although osteoarthritis (OA) of the knee joints is the most common and debilitating joint disease in developed countries, the factors that determine the severity of symptoms are not yet understood well. Subjects with symptomatic medial knee OA were followed up prospectively to explore the relationship between radiographic changes and symptoms or physical examination findings.</p> <p>Methods</p> <p>One-hundred six OA knees in 68 subjects (mean age 71.1 years; 85% women) were followed up at 6-month intervals over 36 months. At each visit, knee radiographs were obtained, symptoms were assessed by a validated questionnaire, and the result of physical examination was recorded systematically using a specific chart. Correlations between the change of radiographs and clinical data were investigated in a longitudinal manner.</p> <p>Results</p> <p>During the study period, the narrowing of joint space width (JSW) was observed in 34 joints (32%). Although those knees were clinically or radiographically indistinguishable at baseline from those without JSW narrowing, differences became apparent at later visits during the follow-up. The subjects with knees that underwent JSW narrowing had severer symptoms, and the symptoms tended to be worse for those with higher rates of narrowing. A significant correlation was not found between the severity of symptoms and the growth of osteophytes. For the knees that did not undergo radiographic progression, the range of motion improved during the follow-up period, possibly due to the reduction of knee pain. Such improvement was not observed with the knees that underwent JSW narrowing or osteophyte growth.</p> <p>Conclusion</p> <p>The result of this study indicates that the symptoms of knee OA patients tend to be worse when JSW narrowing is underway. This finding may explain, at least partly, a known dissociation between the radiographic stage of OA and the severity of symptoms.</p

Learning physical examination skills outside timetabled training sessions: what happens and why?

Lack of published studies on students’ practice behaviour of physical examination skills outside timetabled training sessions inspired this study into what activities medical students undertake to improve their skills and factors influencing this. Six focus groups of a total of 52 students from Years 1–3 using a pre-established interview guide. Interviews were recorded, transcribed and analyzed using qualitative methods. The interview guide was based on questionnaire results; overall response rate for Years 1–3 was 90% (n = 875). Students report a variety of activities to improve their physical examination skills. On average, students devote 20% of self-study time to skill training with Year 1 students practising significantly more than Year 3 students. Practice patterns shift from just-in-time learning to a longitudinal selfdirected approach. Factors influencing this change are assessment methods and simulated/real patients. Learning resources used include textbooks, examination guidelines, scientific articles, the Internet, videos/DVDs and scoring forms from previous OSCEs. Practising skills on fellow students happens at university rooms or at home. Also family and friends were mentioned to help. Simulated/real patients stimulated students to practise of physical examination skills, initially causing confusion and anxiety about skill performance but leading to increased feelings of competence. Difficult or enjoyable skills stimulate students to practise. The strategies students adopt to master physical examination skills outside timetabled training sessions are self-directed. OSCE assessment does have influence, but learning takes place also when there is no upcoming assessment. Simulated and real patients provide strong incentives to work on skills. Early patient contacts make students feel more prepared for clinical practice

Radiological characterisation of photon radiation from ultra-high-intensity laser-plasma and nuclear interactions.

With the increasing number of multi-terawatt (10(12) W) and petawatt (10(15) W) laser interaction facilities being built, the need for a detailed understanding of the potential radiological hazards is required and their impact on personnel is of major concern. Experiments at a number of facilities are being undertaken to achieve this aim. This paper describes the recent work completed on the Vulcan petawatt laser system at the CCLRC Rutherford Appleton Laboratory, where photon doses of up to 43 mSv at 1 m per shot have been measured during commissioning studies. It also overviews the shielding in place on the facility in order to comply with the Ionising Radiation Regulations 1999 (IRR99), maintaining a dose to personnel of less than 1 mSv yr(-1) and as low as reasonably practicable (ALARP)

Ultrafast evolution of electric fields from high-intensity laser-matter interactions

The interaction of high-power ultra-short lasers with materials offers fascinating wealth of transient phenomena which are in the core of novel scientific research. Deciphering its evolution is a complicated task that strongly depends on the details of the early phase of the interaction, which acts as complex initial conditions. The entire process, moreover, is difficult to probe since it develops close to target on the sub-picosecond timescale and ends after some picoseconds. Here we present experimental results related to the fields and charges generated by the interaction of an ultra-short high-intensity laser with metallic targets. The temporal evolution of the interaction is probed with a novel femtosecond resolution diagnostics that enables the differentiation of the contribution by the high-energy forerunner electrons and the radiated electromagnetic pulses generated by the currents of the remaining charges on the target surface. Our results provide a snapshot of huge pulses, up to 0.6 teravolt per meter, emitted with multi-megaelectronvolt electron bunches with sub-picosecond duration and are able to explore the processes involved in laser-matter interactions at the femtosecond timescale