9 research outputs found
Periostin regulates fibrocyte function to promote myofibroblast differentiation and lung fibrosis
- Author
- A Kudo
- A Leask
- A Maatta
- B B Moore
- B Hinz
- BB Moore
- BB Moore
- BB Moore
- BB Moore
- BD Humphreys
- C A Wilke
- C Garcia de Alba
- C Hung
- CJ Scotton
- DH Madsen
- EM Zeisberg
- FJ Martinez
- IE Fernandez
- IO Ajayi
- J Chesney
- J Chesney
- J Xu
- J Xu
- J Yang
- JC Bonner
- JJ Osterholzer
- JP Hutchinson
- K Horiuchi
- K Izuhara
- K K Kim
- K Ruan
- KE Lipson
- KM Antoniou
- KR Kleaveland
- KR Kleaveland
- L Bianchetti
- M Okamoto
- M Schmidt
- M Selman
- M Uchida
- MS Wilson
- N Hashimoto
- NI Reed
- PK Naik
- R Abe
- R Bucala
- R Kalluri
- R Kalluri
- RJ Phillips
- S L Ashley
- SH Phan
- SK Madala
- SL Ashley
- SL Ashley
- T Maruhashi
- TE King Jr.
- TS Blackwell
- VS LeBleu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Anti-fibrotic efficacy of nintedanib in pulmonary fibrosis via the inhibition of fibrocyte activity
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis
- Author
- AA Eddy
- B Reich
- BD Humphreys
- D Orlic
- EM Zeisberg
- F Klingberg
- F Strutz
- FY Ma
- HJ Anders
- I Goren
- I Grgic
- J Li
- J Xiao
- J Yan
- J Yan
- J Yang
- JE Mooney
- JS Duffield
- K Inazaki
- K Jinde
- K Kitamoto
- KR Kleaveland
- LL Falke
- M Broekema
- M Iwano
- M Mack
- PJ Murray
- R Bucala
- S Wang
- SB Haudek
- SD Ricardo
- SE Quaggin
- SJ Forbes
- T Lawrence
- TD Hewitson
- VS LeBleu
- XM Meng
- XM Meng
- XM Meng
- XR Huang
- Y Ikezumi
- Y Ikezumi
- YY Ng
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The role of periostin in lung fibrosis and airway remodeling
- Author
- A Chetta
- A James
- A Kudo
- A Moeller
- A Sood
- American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus
- AT Goodwin
- AY Liu
- B Chen
- B Hinz
- B Moore
- BB Moore
- BB Moore
- BB Moore
- BB Moore
- Bethany B. Moore
- C Blanchard
- C Garcia de Alba
- David N. O’Dwyer
- DH Madsen
- DJ Tschumperlin
- DN O’Dwyer
- DN O’Dwyer
- ED Gordon
- ES White
- FJ Martinez
- G Jia
- G Passalacqua
- G Raghu
- G Takayama
- H Loomis-King
- H Scheerens
- H Tanjore
- HE Trejo Bittar
- HR Collard
- I Noth
- I Suzaki
- J Chesney
- J Chesney
- J Xu
- J Xu
- JE Kolodsick
- JK Bentley
- JM Lopez-Guisa
- JP Bridges
- JP Hutchinson
- JR Stokes
- JS Walsh
- K Horiuchi
- K Izuhara
- K Komiya
- K Ruan
- KM Akram
- KR Kleaveland
- KR Kleaveland
- L Bianchetti
- L Hong
- L Morra
- L Shulgina
- LT McDonald
- M Kuehnel
- M Matsusaka
- M Okamoto
- M Schmidt
- M Uchida
- M Wang
- MA Kim
- MA Seibold
- MK Han
- MS Wilson
- MW Johansson
- MY Armanios
- N Hashimoto
- N Khalil
- N Khalil
- NA Hanania
- PD Bozyk
- PG Woodruff
- PG Woodruff
- PK Naik
- PL Molyneaux
- R Abe
- R Bucala
- RG Jenkins
- RJ Phillips
- RP Naikawadi
- S Bhattacharyya
- S Ohta
- S Sehra
- SA Antoniu
- SK Madala
- SL Ashley
- SS Sidhu
- T Maruhashi
- T Nance
- TE King Jr
- V Lama
- VJ Thannickal
- W Chang
- WE Lawson
- WE Lawson
- Y Aschner
- Y Huang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Impact of a CXCL12/CXCR4 Antagonist in Bleomycin (BLM) Induced Pulmonary Fibrosis and Carbon Tetrachloride (CCl4) Induced Hepatic Fibrosis in Mice
- Author
- A Dar
- A Moeller
- AL Mark
- AM Tager
- B Debnath
- B-S Ding
- Bernard Lo
- Betina Y. Y. Ng
- C Hung
- C Weiler-Normann
- C Ying Jun
- CC Bleul
- CW Hendrix
- D Schols
- Eric Simonson
- F Hong
- FJ Eng
- G Raghu
- G Raghu
- G Raghu
- H Makino
- HJ Dranse
- I Mederacke
- Ingrid Barta
- Irina Manisali
- J Wu
- J Wu
- J Xu
- JA Bjoraker
- Jason Crawford
- JB Crawford
- JJ Egan
- JP Iredale
- JS Song
- Kelly M. McNagny
- KR Kleaveland
- Leola N. Chow
- LP Nicod
- M Watanabe
- Michael R. Hughes
- Murray Webb
- N Hamada
- N Hashimoto
- NC Henderson
- ND Stone
- NI Chaudhary
- O Kollet
- O Wald
- P Ramachandran
- P Spagnolo
- Partha Mukhopadhyay
- Petra Schreiner
- PW Noble
- R. Wilder Scott
- RJ Phillips
- RM Mosi
- RT Skerlj
- S Lim Y-
- Samantha Lecour
- SL Friedman
- SL Friedman
- T Lapidot
- T Nagasawa
- T. Michael Underhill
- TE King
- Vionarica Gusti
- X-D Wang
- Y Saiman
- Y-R Zou
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
The Role of Fibrocytes in Fibrogenic Liver Diseases
- Author
- A Bellini
- A Blakaj
- A Moeller
- A Regev
- AB Farris
- AS Chu
- BB Moore
- BB Moore
- C Balmelli
- C Li
- C Li
- D Pilling
- D Pilling
- D Pilling
- D Scholten
- DA Brenner
- DA Brenner
- DD Shao
- E Seki
- EL Herzog
- G Grieb
- G Nunnari
- H Ikeda
- H Peng
- J Chesney
- J Chesney
- J Xu
- JR Crawford
- JS Duffield
- JS Duffield
- K Taura
- KE Nakken
- KR Kleaveland
- LA Murray
- LA Murray
- LA Murray
- M Fausther
- M Niedermeier
- M Roderfeld
- M Roderfeld
- MV Medeiros
- N Hashimoto
- N Sakai
- N Sakai
- OA Chow
- R Abe
- R Bataller
- R Bucala
- R Bucala
- R Kalluri
- RG Wells
- RM Strieter
- RM Strieter
- S Schwalm
- S Shiohira
- S Yousefi
- SB Haudek
- SK Mathai
- SL Lin
- T Kisseleva
- T Kisseleva
- T Kisseleva
- T Wada
- TA Wynn
- TE Quan
- TE Quan
- V Brinkmann
- WR Lin
- X Liu
- X Xie
- Y Inagaki
- Y Ishida
- Y Li
- Y Takuwa
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The Long Pentraxin PTX3 Promotes Fibrocyte Differentiation
- Author
- A Andersson-Sjöland
- A Doni
- A Doni
- A Ioan-Facsinay
- A Mantovani
- A Mantovani
- AJ Nauta
- AL Hughes
- AP Castano
- AP van Rossum
- AS Maharjan
- AS Maharjan
- AS Maharjan
- AV Misharin
- B Bottazzi
- B Bottazzi
- B Han
- B Mehrad
- BB Moore
- BB Moore
- C Auffray
- C Garlanda
- CY Seiler
- D Bharadwaj
- D Okutani
- D Pilling
- D Pilling
- D Pilling
- D Pilling
- D Pilling
- D Pilling
- D Pilling
- D Verzijl
- Darrell Pilling
- DD Shao
- DM Smadja
- E Banerjee
- ER Job
- F Liu
- F Moalli
- F Nimmerjahn
- F Nimmerjahn
- Gernot Zissel
- GW Lee
- H Teoh
- I Hartlapp
- J Balhara
- J Kitaura
- J Lu
- J Lu
- J Lu
- J Zhang
- J. Sjef Verbeek
- JF Wagenaar
- JF Wang
- JR Crawford
- JR Crawford
- JV Ravetch
- K Boonnak
- KR Kleaveland
- L Bianchetti
- L Deban
- L Mori
- L Yang
- LA Murray
- M Daeron
- M Introna
- M Nebuloni
- M Schmidt
- M van Egmond
- MA Pegues
- MJ van Vugt
- MJV White
- MR Dillingh
- MR Santhiago
- MW Epperly
- N Cox
- N Cox
- N Hashimoto
- N Sakai
- N Sakai
- N Sakai
- NC Direkze
- Nehemiah Cox
- NS Pauwels
- P Boross
- P Boross
- P Bruhns
- P Bruhns
- PN Hawkins
- R Abe
- R Bucala
- RA Reilkoff
- RC Monteiro
- Richard H. Gomer
- RJ Phillips
- RL Varcoe
- S Aiba
- S Jaillon
- S Jaillon
- S Rajagopal
- SB Haudek
- SB Haudek
- SE Cowper
- SE Herlihy
- T Kenakin
- T Kisseleva
- T Sprong
- TE Quan
- Varsha Vakil
- WL Hazenbos
- WL Hutchinson
- X He
- YJ Ma
- ZI Li
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/01/2015
- Field of study
Monocyte-derived, fibroblast-like cells called fibrocytes are associated with fibrotic lesions. The plasma protein serum amyloid P component (SAP; also known as pentraxin-2, PTX2) inhibits fibrocyte differentiation in vitro, and injections of SAP inhibit fibrosis in vivo. SAP is a member of the pentraxin family of proteins that includes C-reactive protein (CRP; PTX1) and pentraxin-3 (PTX3). All three pentraxins are associated with fibrosis, but only SAP and CRP have been studied for their effects on fibrocyte differentiation. We find that compared to SAP and CRP, PTX3 promotes human and murine fibrocyte differentiation. The effect of PTX3 is dependent on FcÎłRI. In competition studies, the fibrocyte-inhibitory activity of SAP is dominant over PTX3. Binding competition studies indicate that SAP and PTX3 bind human FcÎłRI at different sites. In murine models of lung fibrosis, PTX3 is present in fibrotic areas, and the PTX3 distribution is associated with collagen deposition. In lung tissue from pulmonary fibrosis patients, PTX3 has a widespread distribution, both in unaffected tissue and in fibrotic lesions, whereas SAP is restricted to areas adjacent to vessels, and absent from fibrotic areas. These data suggest that the relative levels of SAP and PTX3 present at sites of fibrosis may have a significant effect on the ability of monocytes to differentiate into fibrocytes
Paracrine functions of fibrocytes to promote lung fibrosis
- Author
- Abreu JG
- Aiba S
- Andersson-Sjoland A
- Bartram U
- Baud L
- Bellini A
- Bethany B Moore
- Bonniaud P
- Bornstein P
- Brigstock DR
- Bucala R
- Cabrera S
- Chesney J
- Field JJ
- Fontana L
- Fontana L
- Fuchs Y
- Fujiwara A
- Galligan CL
- Gan Y
- Garcia-de-Alba C
- Garibaldi BT
- Hanumegowda C
- Harris DA
- Hartlapp I
- Hashimoto N
- Horan GS
- Huang C
- Iwamoto N
- Kalluri R
- Kao HK
- Kathryn R Kleaveland
- Kevin K Kim
- Kisseleva T
- Kolodsick JE
- LaPar DJ
- Leask A
- Leask A
- Leitinger B
- Levental KR
- Lipson KE
- Mani SA
- Mason RJ
- Mathai SK
- Mehrad B
- Moore BB
- Morel AP
- Myllyharju J
- Nemzek JA
- Oikonomidi S
- Olaso E
- Ozaki T
- Phan SH
- Pilling D
- Puthawala K
- Quan TE
- Rafii R
- Rawlins EL
- Rawlins EL
- Rawlins EL
- Saunders R
- Savagner P
- Schmeckebier S
- Schmidt M
- Schmidt M
- Sonnylal S
- Strieter RM
- Swiderski RE
- Takase HM
- Tanjore H
- Tourkina E
- Tourkina E
- Tschumperlin DJ
- van Deventer HW
- Vannella KM
- Wan YY
- Wang CH
- Wang JF
- Wang R
- Wardlaw AJ
- Weng CM
- Wilborn J
- Wilborn J
- Wipff PJ
- Wipff PJ
- Xu J
- Zeisberg EM
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Cardiovascular Activity
- Author
- A Baartscheer
- A Baartscheer
- A Baartscheer
- A Bachmann
- A Bauer
- A Bergdahl
- A Bezold von
- A Biedl
- A Bomzon
- A Bonnacrossi
- A Braillon
- A Brkovic
- A Brueggemann
- A BrĂĽggemann
- A Bucchi
- A Capri
- A Carmeliet
- A Carotenuto
- A Cavalié
- A Cavalli
- A Chatelier
- A Chu
- A Claing
- A Daugherty
- A Daugherty
- A Daugherty
- A Ezzaher
- A Fabiato
- A Fleckenstein
- A Fleckenstein
- A Fleckenstein
- A Fleckenstein
- A Fleckenstein
- A Fleckenstein
- A Gagliardi
- A Genao
- A Genovese
- A Gibson
- A Gibson
- A Gibson
- A Goll
- A Grassegger
- A Graziani
- A Grollman
- A Haugan
- A Hedberg
- A Helman
- A Hilditch
- A Hilditch
- A Hilditch
- A Hislop
- A Hislop
- A Hutchaleelaha
- A Inoue
- A Inoue
- A Inoue
- A Jarisch
- A Jarisch
- A Jarisch
- A Karlin
- A Kasai
- A Kochhar
- A Lerman
- A Lopez de Leon
- A Luchner
- A Luchner
- A LĂĽckhoff
- A LĂĽckhoff
- A Malhotra
- A Marchese
- A Marjamäki
- A Marmarou
- A Mattes
- A McRae
- A Menargues
- A Miwa
- A Molteni
- A Molteni
- A Molteni
- A Molteni
- A Monopoli
- A Morita
- A MĂĽlsch
- A Nygren
- A Osajima
- A Reaux
- A Reaux
- A Rudolph
- A Rutledge
- A Salimbeni
- A Sanbe
- A Sattin
- A Schuster
- A Schömig
- A Sculptoreanu
- A Sgoifo
- A Shiroshita-Takeshita
- A Stirrat
- A Sunami
- A Tajima
- A Tamura
- A Terzic
- A Tzanidis
- A Vacca
- A Vacca
- A Vaille
- A Vegh
- A Vegh
- A Verma
- A Volovsek
- A Wahhab
- A Ward
- A Wollenberger
- A Woppmann
- A Wright
- A Yu
- AA Andreadis
- AA Kochegarow
- AA Owji
- AA Pieper
- AB Fawzi
- AB Schreiber
- AB Schreiber
- AB Steffens
- AC Chiou
- AC Dolphin
- AC MacKinnon
- AC MacKinnon
- AC Sulpizio
- ACG Uprichard
- ACG Uprichard
- AD Medhurst
- AD Michel
- AD Michel
- AD Muskett
- AD Muskett
- AE Busch
- AE Busch
- AE Freedlender
- AE RiberoMO
- AEFH Meijer
- AF Green
- AF Green
- AF Green
- AF Green
- AF Green
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- AJ Bold De
- AJ Carter
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- AJ Gower
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- AJ Kaumann
- AJ Kielblock
- AJ King
- AJ Newell
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- AJ Pijl
- AJ Rice
- AJ Susswein
- AJ SzentmiklĂłsi
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- AL Blatz
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- U Benelli
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- Wienen W Hauel N, van Meel JCA, Narr B, Ries U, Entzeroth M (1993) Pharmacological characterization of the novel nonpeptide angiotensin II receptor antagonist, BIBR 277. Br J Pharmacol 110:245–252 Wong PC, Quan ML, Saye JAM, Bernard R, Crain EJ Jr, Nc- Call DE, Watson CA, Zaspel AM, Smith RD, Wexler RR, Timmermans PBMWM, Chiu AT
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2007
- Field of study