CERTIFICATION REPORT The certification of the mass fraction of arsenobetaine in water: ERM®-AC626

This report describes the production of ERM-AC626, an aqueous solution material certified for the mass fraction of arsenobetaine (AB). The material was produced following ISO Guide 34:2009. The starting material was 10 g of solid AB monohydrate. The purity of AB was assessed through measurements carried out by laboratories of demonstrated competence and within the scope of accreditation to ISO/IEC 17025:2005. An aqueous solution was prepared and ampouled into 2 mL amber glass ampoules under argon atmosphere. Between unit-homogeneity was quantified and stability during dispatch and storage were assessed in accordance with ISO Guide 35:2006. Due to the inherent homogeneity of water solutions, determination of minimum sample intake (within-unit homogeneity) was not required. The sample intake used in the homogeneity study was adopted as the recommended minimum sample intake. The minimum sample intake is 50 µg. The certified value was obtained from the gravimetric preparation of the solution, taking into account the purity of the starting material. The certified value was confirmed by independent analyses carried out by laboratories of demonstrated competence and adhering to ISO/IEC 17025. Uncertainties of the certified values were calculated in compliance with the Guide to the Expression of Uncertainty in Measurement (GUM) and include uncertainties related to possible inhomogeneity and instability and to characterisation. The material is intended to be used as a calibrant and quality control sample. The CRM is available in amber glass ampoules containing 1 mL of AB aqueous solution closed under argon atmosphere. The minimum amount of sample to be used is 50 µg. The CRM was accepted as European Reference Material (ERM®) after peer evaluation by the partners of the European Reference Materials consortium.JRC.F.6-Reference Material

CERTIFICATION REPORT: The certification of the mass fractions of elements in Trout Muscle: ERM-CE101

This report describes the production of ERM-CE101, which is a matrix material certified for the mass fractions of elements. This material was produced following ISO Guide 34:2009 [ ] and is certified in accordance with ISO Guide 35:2006 [2]. The material was produced from fresh fish muscle from both trout and Nile perch. Batches of the fish muscle were frozen and cryogenically milled before being blended in mixing/cutting equipment. The resulting paste was pre-cooked and filled into glass jars. The jars were capped and autoclaved to ensure preservation of the sample. Between unit-homogeneity was quantified and stability during dispatch and storage were assessed in accordance with ISO Guide 35:2006 [ ]. Within-unit homogeneity was quantified to determine the minimum sample intake. The material was characterised by an interlaboratory comparison of laboratories of demonstrated competence and adhering to ISO/IEC 17025. Technically invalid results were removed but no outlier was eliminated on statistical grounds only. Uncertainties of the certified values were calculated in accordance with the Guide to the Expression of Uncertainty in Measurement (GUM) [ ] and include uncertainties related to possible inhomogeneity, instability and characterisation. The material is intended for quality control and assessment of method performance. As with any reference material, it can be used for establishing control charts or validation studies. The CRMs is available in glass jars containing at least 40 g of homogenised fish muscle, which were sealed with a pop-up safety lid. The minimum amount of sample to be used is 500 mg.JRC.F.6-Reference Material

Разпространение на хронично бъбречно заболяване сред населението на град Варна, Община Вълчи дол и Община Аврен

В световен мащаб хроничното бъбречно заболяване (ХБЗ) представлява нарастващ по тежест здравословен и икономически проблем. Според данните от Световния бъбречен ден близо 850 милиона хора по света страдат от ХБЗ с различна етиология, като 2,4 милиона души годишно умират от бъбречни заболявания. Тази честота поставя ХБЗ като 6-ата най-бързо зачестяваща причина за смъртност сред населението. Във финансов план лечението на терминалната бъбречна недостатъчност (ESRD) представлява огромна тежест за всяка държава, като хемодиализата се нарежда сред най-натоварващите бюджета на една държава вид лечение. По повод Световния бъбречен ден 2019 (14 март), Клиниката по нефрология на УМБАЛ „Св. Марина“ – Варна проведе безплатна скрининг кампания сред населението на град Варна, като поради големия интерес бяха обхванати и две общини във Варненска област – Аврен и Вълчи дол. Целта на програмата с мото „Здраве за всеки, навсякъде“ бе да открие латентно протичащи бъбречни заболявания, да акцентира върху най-сериозните рискови фактори, които биха довели до развитието на ХБЗ, както и да изостри вниманието на обществото към провежданата паралелно с програмата инициатива за донорство и трансплантация. В резултат на проведената кампания бяха обхванати общо 195 души, като при 75 от тях се откри хронично бъбречно заболяване, а 120 бяха без обективни данни за бъбречна патология. Получените данни дават основание да се смята, че са необходими по-мащабни стратегии за диагностика и превенция на хроничното бъбречно заболяване, което би се отразило благоприятно както върху здравния статус на населението, така и на финансовото и икономическо положение на държавата

Abstracts Of The Proceedings And The Posters From The Third Scientific Session Of The Medical College Of Varna

October 2-3, 201