The Distribution of game in Uganda

Volume: I

Initial Clinical Referral Standards after Newborn Screening for Congenital Hypothyroidism: Final Report of the UK Newborn Screening Programme Centre Expert Working Group and Systematic Evidence Review 2010-2011.

Background In April 2010, the Initial Clinical Referral Standards (ICR) for Congenital Hypothyroidism (CHT) Expert Working Group was convened as a sub-group of the Joint Standing Committee for Congenital Hypothyroidism (CHT JSC) to review and revise the UK National Screening Programme Initial Clinical Referral Standards after Newborn Screening for Congenital Hypothyroidism. The work commenced with a systematic review of the published evidence undertaken by Dr R Knowles and Ms F Olafsdottir. The Expert Working Group reviewed and recommended revisions to the existing (2005) UKNSPC standards and guidelines to support confirmatory diagnosis and initial management for babies in whom CHT is suspected. This included a review of current CHT screening policy and UK performance against national standards and European standards and guidelines. The Expert Working Group, chaired by Dr T Cheetham (Consultant Paediatric Endocrinologist), met on four occasions between July 2010 and September 2011 to review and revise the referral standards. Scope of the review To support the review process with evidence review and expert consensus where published evidence is lacking, focusing on the following topic areas: • Screening test performance and indications for referral • Diagnostic schedule for confirmatory diagnosis of CHT • Initial treatment and frequency of follow up to the point of diagnosis or definitive management • Communication flows • Communication with parents Public Consultation A public consultation was carried out in May/June 2012 and subsequent changes to the standards on the basis of the responses are included in this final version of the report. Summary and Recommendations The subgroup’s final recommendations were endorsed by the Joint Standing Committee and Blood Spot Advisory Group (BSAG) and submitted to the Fetal Maternal and Child Health Subgroup of the National Screening Committee (NSC) for approval of changes to current screening policy and standards. This final report presents the revised standards, screening protocol and diagnostic protocol developed by the Expert Working Group and finalised after public consultation, as well as the evidence basis for the revised standards and guidelines

Probing quasiparticle excitations in a hybrid single electron transistor

We investigate the behavior of quasiparticles in a hybrid electron turnstile with the aim of improving its performance as a metrological current source. The device is used to directly probe the density of quasiparticles and monitor their relaxation into normal metal traps. We compare different trap geometries and reach quasiparticle densities below 3um^-3 for pumping frequencies of 20 MHz. Our data show that quasiparticles are excited both by the device operation itself and by the electromagnetic environment of the sample. Our observations can be modelled on a quantitative level with a sequential tunneling model and a simple diffusion equation

A Potential Representation for Two-Dimensional Waves in Elastic Materials of Harmonic Type

In the present note we consider two-dimensional finite dynamical deformations for the class of homogeneous, isotropic elastic materials introduced by F. John in [1] and referred to by him as materials of harmonic type. The theory of such materials, developed in [1] and [2], appears to be simpler in many respects than that of more general elastic materials, and it may offer the possibility of investigating some features of nonlinear elastic behavior more explicitly than is possible in general. For plane motions of such materials, we derive here a representation for the displacements in terms of two potentials which is analogous to the theorem of Lamé in classical linear elasticity (see [3]) for the case of plane strain. The two nonlinear differential equations satisfied by the potentials reduce upon linearization to the wave equations associated with irrotational and equivoluminai waves in the linear theory. In the following section we state without derivation the equations governing two-dimensional waves in an elastic material of harmonic type. The reader is referred to [1] for details. In Sec. 3 we derive the representation in terms of potentials described briefly above

Novel sol–gel preparation of (PO)–(CaO)–(NaO)–(TiO) bioresorbable glasses (X = 0.05, 0.1, and 0.15)

Quaternary phosphate-based glasses in the PO–CaO–NaO–TiO system with a fixed PO and CaO content of 40 and 25 mol% respectively have been successfully synthesised via sol–gel method and bulk, transparent samples were obtained. The structure, elemental proportion, and thermal properties of stabilised sol–gel glasses have been characterised using X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDX), P nuclear magnetic resonance (P NMR), titanium K-edge X-ray absorption near-edge structure (XANES), fourier transform infrared (FTIR) spectroscopy, and differential thermal analysis (DTA). The XRD results confirmed the amorphous nature for all stabilized sol–gel derived glasses. The EDX result shows the relatively low loss of phosphorus during the sol–gel process and Ti K-edge XANES confirmed titanium in the glass structure is in mainly six-fold coordination environment. The P NMR and FTIR results revealed that the glass structure consist of mainly Q and Q phosphate units and the Ti cation was acting as a cross-linking between phosphate units. In addition DTA results confirmed a decrease in the glass transition and crystallisation temperature with increasing NaO content. Ion release studies also demonstrated a decrease in degradation rates with increasing TiO content therefore supporting the use of these glasses for biomedical applications that require a degree of control over glass degradation. These sol–gel glasses also offer the potential to incorporate proactive molecules for drug delivery application due to the low synthesis temperature employed

Method of Monte Carlo grid for data analysis

This paper presents an analysis procedure for experimental data using theoretical functions generated by Monte Carlo. Applying the classical chi-square fitting procedure for some multiparameter systems is extremely difficult due to a lack of an analytical expression for the theoretical functions describing the system. The proposed algorithm is based on the least square method using a grid of Monte Carlo generated functions each corresponding to definite values of the minimization parameters. It is used for the E742 experiment (TRIUMF, Vancouver, Canada) data analysis with the aim to extract muonic atom scattering parameters on solid hydrogen.Comment: 16 pages, 10 figures, submitted to NI

Bark beetle impacts on remotely sensed evapotranspiration in the Colorado Rocky Mountains

January 2019.Includes bibliographical references.Bark beetles represent a major ongoing forest disturbance throughout the southern Rocky Mountains with unknown implications for hydrological partitioning between the abiotic (evaporation) and biotic (transpiration) components of the total evapotranspiration (ET) flux. Since changes in ET are linked to both groundwater and surface water recharge processes, this scenario has the potential to affect water delivery to agricultural, industrial, and residential consumers downstream. Accordingly, this research used satellite remote sensing, eddy covariance, and hydrological modeling approaches to independently quantify the impact of bark beetles on growing season ET, the transpiration fraction of ET (T/ET), and streamflow across a range of spatial scales throughout the 144,462 km2 EPA Level III Southern Rocky Mountain ecoregion. The results of this work demonstrate statistically significant post-disturbance ET reductions between 9% (remote sensing) and 28% (eddy covariance) relative to pre-disturbance conditions. Further, commensurate decreases in transpiration and T/ET from disturbed areas suggest that the total ET flux was primarily sensitive to changes in transpiration. In the context of the water balance, the Variable Infiltration Capacity (VIC) hydrological model simulated decreased canopy interception and increased soil moisture as a result of beetle disturbance, which increased streamflow by 9%. Factoring in the number of grid cells that were disturbed, bark beetles decreased ET by 62,000 acre-feet and increased streamflow by 54,000 acre-feet between 2000 and 2013. These results will benefit water managers tasked with forecasting water resources from disturbed areas both now and in the future