Numerical study of hydrodynamic characteristics of gas liquid slug flow in vertical pipes

Multiphase flows occur in wide applications including; nuclear, chemical, and petroleum industries. One of the most important flow regime encountered in multiphase flow is the slug flow which is often encountered in oil and gas production systems. The slugging problems may cause flooding of downstream processing facilities, severe pipe corrosion and the structural instability of pipeline and further induce the reservoir flow oscillations, and a poor reservoir management. In the present study, computational fluid dynamics simulation is used to investigate two phase slug flow in vertical pipe using the volume of fluid (VOF) methodology implemented in the commercial code ANSYS Fluent. Theviscous, inertial, and interfacial forces have the significant effect on the hydrodynamic characteristics of two-phase slug flow. These forces can have investigated by introducing a set of dimensionless numbers, namely; inverse viscosity number, Nf, Eotvos number, Eo, and Froude number, FrTB. The simulation accounts for the hydrodynamic features of two phase slug flow including; the shape of Taylor bubble, bubble profile, velocity and thickness of the falling film, wake flow pattern, and wall shear stress distribution. The CFD simulation results are in good agreement with previous experimental data and models available in literature

Modeling intracranial aneurysm stability and growth: An integrative mechanobiological framework for clinical cases

We present a novel patient-specific fluid-solid-growth framework to model the mechanobiological state of clinically detected intracranial aneurysms (IAs) and their evolution. The artery and IA sac are modeled as thick-walled, non-linear elastic fiber-reinforced composites. We represent the undulation distribution of collagen fibers: the adventitia of the healthy artery is modeled as a protective sheath whereas the aneurysm sac is modeled to bear load within physiological range of pressures. Initially, we assume the detected IA is stable and then consider two flow-related mechanisms to drive enlargement: (1) low wall shear stress; (2) dysfunctional endothelium which is associated with regions of high oscillatory flow. Localized collagen degradation and remodelling gives rise to formation of secondary blebs on the aneurysm dome. Restabilization of blebs is achieved by remodelling of the homeostatic collagen fiber stretch distribution. This integrative mechanobiological modelling workflow provides a step towards a personalized risk-assessment and treatment of clinically detected IAs