Adenomatoid mesothelioma arising from the diaphragm: a case report and review of the literature

Background Adenomatoid mesothelioma is a rare subtype of malignant mesothelioma that can be confused with adenomatoid tumors, which are classified as benign. The clinical features and optimal management of adenomatoid mesothelioma have not been elucidated in the literature. In this report, we present an extremely rare case of adenomatoid mesothelioma that developed on the peritoneal surface of the diaphragm as well as a literature review of adenomatoid mesothelioma in the abdominal cavity. Case presentation The patient was a 61-year-old Japanese woman who had undergone resection of a malignant peripheral nerve sheath tumor of the hand 18 years prior. She was diagnosed with clinical stage I lung adenocarcinoma on follow-up chest radiography. Simultaneously, a 20-mm enhancing nodule with slow growth on the right diaphragm was detected on contrast-enhanced computed tomography. She presented no specific clinical symptoms. At this point, the lesion was suspected to be a hypervascular tumor of borderline malignancy, such as a solitary fibrous tumor. After a left upper lobectomy for lung adenocarcinoma, she was referred to our department, and laparoscopic tumor resection was performed. Adenomatoid tumors were also considered based on the histopathological and immunohistochemical analyses, but we made the final diagnosis of adenomatoid mesothelioma using the results of the genetic profile. The patient remains alive, with no recurrence noted 6 months after surgery. Conclusion We encountered a valuable case of adenomatoid mesothelioma of peritoneal origin. There are some previously reported cases of adenomatoid mesothelioma and adenomatoid tumors that may need to be recategorized according to the current classification. It is important to accumulate and share new findings to clarify the clinicopathological characteristics and genetic status of adenomatoid mesothelioma

Spacetime dynamics and baryogenesis in braneworld

We point out that the effective theory for the Randall-Sundrum braneworld models with bulk fields contains the baryon number violation process depending on the spacetime dynamics. Combining to the curvature-current interaction, the net baryon number observed today may be explained. The resultant baryon to entropy ratio is determined by the ratio of the Planck scales in four dimensional and five dimensional spacetime except for the parameter for CP violation.Comment: 8 pages, references adde

Higgs Boson Mass in Low Scale Gauge Mediation Models

We consider low scale gauge mediation models with a very light gravitino m_{3/2}~16 eV, in the light of recent experimental hints on the Higgs boson mass. The light gravitino is very interesting since there is no gravitino over-production problem, but it seems difficult to explain the Higgs boson mass of ~125 GeV. This is because of the conflict between the light gravitino mass and heavy SUSY particle masses needed for producing the relatively heavy Higgs boson mass. We consider two possible extensions in this paper: a singlet extension of the Higgs sector, and strongly coupled gauge mediation. We show that there is a large parameter space, in both scenarios, where the Higgs boson mass of ~125 GeV is explained without any conflict with such a very light gravitino.Comment: 23 pages, 5 figure

Aspects of Non-minimal Gauge Mediation

A large class of non-minimal gauge mediation models, such as (semi-)direct gauge mediation, predict a hierarchy between the masses of the supersymmetric standard model gauginos and those of scalar particles. We perform a comprehensive study of these non-minimal gauge mediation models, including mass calculations in semi-direct gauge mediation, to illustrate these features, and discuss the phenomenology of the models. We point out that the cosmological gravitino problem places stringent constraints on mass splittings, when the Bino is the NLSP. However, the GUT relation of the gaugino masses is broken unlike the case of minimal gauge mediation, and an NLSP other than the Bino (especially the gluino NLSP) becomes possible, relaxing the cosmological constraints. We also discuss the collider signals of the models.Comment: 56 pages, 8 figures; v2:minor corrections, references added; v3:minor correction

Super-resolution for a dispersive spectrometer using a tilted area sensor and spectrally varying blur kernel interpolation

The grating, lens, and linear sensor determine a spectrometer’s wavelength resolution and measurement range. While conventional methods have tried to improve the optical design to obtain a better resolution, they have a limitation caused by the physical property. To improve the resolution, we introduce a super-resolution method from the computer vision field. We propose tilting an area sensor to realize accurate subpixel shifting and recover a high-resolution spectrum using interpolated spectrally varying kernels. We experimentally validate that the proposed method achieved a hig

Recovering temporal PSF using ToF camera with delayed light emission

Abstract Recovering temporal point spread functions (PSFs) is important for various applications, especially analyzing light transport. Some methods that use amplitude-modulated continuous wave time-of-flight (ToF) cameras are proposed to recover temporal PSFs, where the resolution is several nanoseconds. Contrarily, we show in this paper that sub-nanosecond resolution can be achieved using pulsed ToF cameras and an additional circuit. A circuit is inserted before the illumination so that the emission delay can be controlled by sub-nanoseconds. From the observations of various delay settings, we recover temporal PSFs of the sub-nanosecond resolution. We confirm the effectiveness of our method via real-world experiments

Differential effects of sodium-glucose cotransporter 2 inhibitor and low-carbohydrate diet on body composition and metabolic profile in obese diabetic db/db mice

Introduction Treatment using sodium-glucose cotransporter (SGLT) 2 inhibitor and low-carbohydrate diet (LCD) for obesity and type 2 diabetes are similar in terms of carbohydrate limitation. However, their mechanisms of action differ, and the effects on the body remain unclear. We investigated the effects of SGLT2 inhibitor and LCD on body composition and metabolic profile using the db/db mouse model for obesity and type 2 diabetes.Research design and methods Eight-week-old male db/db mice were divided into four groups: mice receiving normal diet and vehicle or canagliflozin (Cana) administration and mice receiving LCD and vehicle or Cana administration for 8 weeks. Consumed calories were adjusted to be equal among the groups.Results Both Cana administration and LCD feeding resulted in significant weight gain. Cana administration significantly decreased plasma glucose levels and increased plasma insulin levels with preservation of pancreatic β cells. However, LCD feeding did not improve plasma glucose levels but deteriorated insulin sensitivity. LCD feeding significantly reduced liver weight and hepatic triglyceride content; these effects were not observed with Cana administration. Combined treatment with LCD did not lead to an additive increase in blood β-ketone levels.Conclusions SGLT2 inhibitors and LCD exert differential effects on the body. Their combined use may achieve better metabolic improvements in obesity and type 2 diabetes