502 research outputs found
Mechanism of oxygen release from Li-rich cathode material for lithium ion batteries
For further wide spread of high energy density batteries, one of the most important technological challenges is preventing thermal runaway. For that, a key phenomenon is the oxygen release from cathode active materials, because released oxygen may react with the organic solvent and generate heat. Therefore, it is important to understand the mechanism of oxygen release to ensure safe battery operation. While the reaction of charged cathode material and organic solvent was investigated well [1], the mechanism of oxygen release from cathode material is not understood so far [2]. In this study, oxygen release behavior of Li-rich cathode material Li1.2Mn0.6Ni0.2O2-d was investigated, and the mechanism of oxygen release was discussed based on defect chemistry and thermodynamics.
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Assessment of biological dosimetric margin for stereotactic body radiation therapy
Purpose: To develop a novel biological dosimetric margin (BDM) and to create a biological conversion factor (BCF) that compensates for the difference between physical dosimetric margin (PDM) and BDM, which provides a novel scheme of a direct estimation of the BDM from the physical dose (PD) distribution.
Methods: The offset to isocenter was applied in 1‐mm steps along left‐right (LR), anterior‐posterior (AP), and cranio‐caudal (CC) directions for 10 treatment plans of lung stereotactic body radiation therapy (SBRT) with a prescribed dose of 48 Gy. These plans were recalculated to biological equivalent dose (BED) by the linearquadratic model for the dose per fraction (DPF) of d = 3–20 Gy/fr and α/β= 3 - 10. BDM and PDM were defined so that the region that satisfied that the dose covering 95% (or 98%) of the clinical target volume was greater than or equal to the 90% of the prescribed PD and BED, respectively. An empirical formula of the BCF was created as a function of the DPF.
Results: There was no significant difference between LR and AP directions for neither the PDM nor BDM. On the other hand, BDM and PDM in the CC direction were significantly larger than in the other directions. BCFs of D95% and D98% were derived for the transverse (LR and AP) and longitudinal (CC) directions.
Conclusions: A novel scheme to directly estimate the BDM using the BCF was developed. This technique is expected to enable the BED‐based SBRT treatment planning using PD‐based treatment planning systems
Fast deuteron diagnostics using visible light spectra of 3He produced by deuteron–deuteron reaction in deuterium plasmas
The fast deuteron (non-Maxwellian component) diagnostic method, which is based on the higher resolution optical spectroscopic measurement, has been developed as a powerful tool. Owing to a decrease in the D–H charge-exchange cross section, the diagnostic ability of conventional optical diagnostic methods should be improved for ∼MeV energy deuterons. Because the 3He–H charge-exchange cross section is much larger than that of D–H in the ∼MeV energy range, the visible light (VIS) spectrum of 3He produced by the dueteron–dueteron (DD) reaction may be a useful tool. Although the density of 3He is small because it is produced via the DD reaction, improvement of the emissivity of the VIS spectrum of 3He can be expected by using a high-energy beam. We evaluate the VIS spectrum of 3He for the cases when a fast deuteron tail is formed and not formed in the ITER-like beam injected deuterium plasma. Even when the beam energy is in the MeV energy range, a large change appears in the half width at half maximum of the VIS spectrum. The emissivity of the VIS spectrum of 3He and the emissivity of bremsstrahlung are compared, and the measurable VIS spectrum is obtained. It is shown that the VIS spectrum of 3He is a useful tool for the MeV beam deuteron tail diagnostics
Investigation into Systematized Teaching Method Between a University and Attached School in Teacher Training for Teaching Technology.
教育実習は教員養成における教科に関しての専門的知識,実践的指導力の育成に大きく関わると考えられている。また,単数の専任教員が指導する技術科において,大学・学部と学校現場の連携は非常に重要である。本研究では,教育実習における技術科教員養成のための体系的な指導方法を検討・試行することを目的とし,到達目標および指導方法の検討と,学生が教育実習時に自己評価するための「授業評価チェックシート」を開発した。授業評価チェックシートは,技術科の教育実習で身に付けられる実践的指導力を整理し,授業観察,学習指導案の作成,模擬授業,授業実践時に用いることができるように構成した。そして,この授業評価チェックシートを用いた指導方法を附属学校で統一し,教育実習関連科目での観察実習や授業実践の場面で実践した。その結果,2期制の教育実習において,附属学校教員がそれぞれの到達目標や方法をもとに学生に指導することができ,それぞれの学校で一貫した指導ができた。「授業評価チェックシート」を用いることで,技術科教員として身に付けるべき資質や能力を学生が自己分析することができ,実践的指導力の向上に貢献できると考えられる。The purpose of this study is to examine the teaching method for student teachers of technology in teaching practice. We developed a “Lesson Evaluation Check Sheet” for student teachers of technology to self-evaluate lessons at the time of educational practice. This sheet was constructed so that practical leadership skills acquired in the teaching practice of the technical department can be categorized and used for lesson observation and lesson practice. We used this sheet in observation practice and teaching practice in the courses related to teaching practice. As a result, attached school teachers were able to instruct students based on our methods in their teaching practice. Furthermore, students were able to self-evaluate the qualities and abilities the students should possess using the “Lesson Evaluation Check Sheet”. We believe that this check sheet will contribute to improving students’ practical leadership skills
E-selectin as a prognostic factor of patients hospitalized due to acute inflammatory respiratory diseases
When examining patients with acute inflammatory respiratory diseases, it is difficult to distinguish between infectious pneumonia and interstitial pneumonia and predict patient prognosis at the beginning of treatment. In this study, we assessed whether endothelial selectin (E-selectin) predicts the outcome of patients with acute inflammatory respiratory diseases. We measured E-selectin serum levels in 101 patients who were admitted to our respiratory care unit between January 2013 and December 2013 because of acute inflammatory respiratory diseases that were eventually diagnosed as interstitial pneumonia (n = 38) and lower respiratory tract infection (n = 63). Seven of these patients (n = 101) died. The pneumonia severity score was significantly higher and the oxygen saturation of arterial blood measured by pulse oximeter (SpO2)/fraction of inspiratory oxygen (FiO2) was significantly lower in the deceased patients than in the surviving patients. There were significantly fewer peripheral lymphocytes and significantly higher E-selectin serum levels in the deceased patients than in the surviving patients. In the multiple logistic regression analysis, the E-selectin serum levels and SpO2/FiO2 ratio were independent predictive factors of prognosis. The risk of death during acute respiratory disease was determined using a receiver operating characteristic (ROC) curve analysis. The area under the curve (AUC) was 0.871 as calculated from the ES, and the cutoff value was 6453.04 pg/ml, with a sensitivity of 1.00 and a specificity of 0.72 (p = 0.0027). E-selectin may be a useful biomarker for predicting the prognosis of patients with acute inflammatory respiratory diseases
MafB silencing in macrophages does not influence the initiation and growth of lung cancer induced by urethane
An increased number of tumor-associated macrophages (TAMs) that exhibit the M2 macrophage phenotype is related to poorer prognosis in cancer patients. MafB is a transcription factor regulating the differentiation of macrophages.
However, involvement of MafB for the development of TAMs is unknown. This study was designed to
investigate the role of MafB in a murine urethane-induced lung cancer model. Urethane was injected intraperitoneally into wild-type and dominant-negative MafB transgenic mice. Twenty-four weeks later, mice were sacrificed and their lungs removed for pathological analysis. The numbers and mean areas of lung cancer were evaluated. In addition, the numbers of Mac-3-positive macrophages were evaluated in each tumor. The numbers and mean areas of lung cancer induced by urethane administration were not significantly different between wild-type and dominant-negative MafB transgenic mice. The numbers of TAMs in lung cancer tissue were not significantly different between the two groups. MafB silencing using dominant-negative MafB did not influence the initiation and growth of lung cancer in mice exposed to urethane. These data suggest that MafB may not be related to the development of TAMs
Indirect energy transfer channel between fast ions via nuclear elastic scattering observed on the large helical device
An energy transfer phenomenon between energetic ions, which cannot be explained only considering the Coulomb scattering process, was observed on a large helical device (LHD). This phenomenon often occurs in fusion reactivity enhancement and fast-ion slowing-down process that can be observed as a delay in the decay time of the D(d,n)3He neutron generation rate. The transferred energy required to induce such a reactivity enhancement or delay in the fast-ion slowing-down time (neutron decay time) was examined based on the Boltzmann−Fokker−Planck analysis in which a discrete energy transfer process, called nuclear elastic scattering (NES), is included. It was shown that even though the cross section of the NES is smaller than that of the Coulomb scattering, enough knock-on population appears in the energetic region in ion distribution function to induce the observable NES effects; thus, enough energy is transferred from beam ions to fast component of bulk ion distribution function indirectly and the transferred energy per unit time via NES is comparable to the Coulomb scattering rate. This study analytically demonstrates that the observed phenomena on LHD can be explained smoothly by considering the alternative indirect energy transfer channel between energetic ions, which can be comparable with the one via Coulomb scattering
Functional tooth number and mortality
Aim: Previous studies on the association between intraoral conditions and mortality in community-dwelling older individuals reported that fewer present teeth (PT) are significant risk factors for mortality. However, how the number of PT relative to the number of functional teeth (FT), including both present and rehabilitated teeth, influences mortality has not been investigated fully. This study examined the impact of the number of FT on mortality among community-dwelling Japanese older adults.
Methods: This study was a retrospective, observational and population-based follow-up study, which examined 1188 older individuals who participated in an annual geriatric health examination from 2009 to 2015. The average follow-up period was 1697.0 ± 774.5 days. The primary outcome was all-cause mortality at follow-up. The numbers of PT and FT of each participant were counted during an oral examination. In addition, demographics, clinical variables, blood nutrient markers, physical functions and perceived masticatory function were measured.
Results: Kaplan–Meier analysis, followed by a log-rank test, revealed that fewer PT (P < 0.001) and FT (P = 0.002) were significantly associated with a reduced survival rate. Cox's proportional hazard analysis indicated that the number of FT, but not the number of PT, was a significant independent mortality risk factor after adjusting for demographics, clinical variables, nutrient markers and physical functioning (P = 0.036, hazard ratio: 2.089).
Conclusions: Current results suggest that the number of FT more strongly predicts all-cause mortality than the number of PT among community-dwelling older adults. Further studies are necessary to consider the confounding of socioeconomic status and disability status
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