15 research outputs found
Immunological and parasitological parameters after treatment with dexamethasone in murine Schistosoma mansoni
This work aimed to evaluate the effect of diphenyl dimethyl bicarboxylate (DDB) and dexamethasone alone and in combination with praziquantel on various parasitological, immunological and pathological parameters reflecting disease severity and morbidity in murine schistosomiasis. DDB and dexamethasone had no effect on worm burden but altered tissue egg distribution. This indicates that, under the schedule used, neither drug interfered with the development of adult worms or oviposition, but both can modulate liver pathology. Dexamethasone resulted in a greater reduction in granuloma size than did DDB. Dexamethasone-treated mice also showed lower levels of serum gamma interferon (IFN-γ), interleukin-12 (IL-12) and IL-4, together with higher IL-10 levels, than infected untreated control animals. These data suggest that dexamethasone is a convenient and promising coadjuvant agent that results in decreased morbidity in murine schistosomiasis
Green Criminology Before ‘Green Criminology’: Amnesia and Absences
Although the first published use of the term ‘green criminology’ seems to have been made by Lynch (Green criminology. Aldershot, Hampshire, 1990/2006), elements of the analysis and critique represented by the term were established well before this date. There is much criminological engagement with, and analysis of, environmental crime and harm that occurred prior to 1990 that deserves acknowledgement. In this article, we try to illuminate some of the antecedents of green criminology. Proceeding in this way allows us to learn from ‘absences’, i.e. knowledge that existed but has been forgotten. We conclude by referring to green criminology not as an exclusionary label or barrier but as a symbol that guides and inspires the direction of research
Climate Change and Peacemaking Criminology: Ecophilosophy, Peace and Security in the ?War on Climate Change?
Some commentators have recently sought to cast climate change as primarily an issue of national security, thereby necessitating a "war on climate change." In this article, we argue that the adoption of a securitizing and war-making approach is problematic in that it proposes solutions that parallel the very human actions that contribute to climate change. Because the securitizing responses to the problem of climate change only further the hierarchical domination that contributes to the problem, we contend that we must approach climate change from a critical perspective informed by peacemaking and liberation rather than war-making. Given the harms attendant to war, neoliberal capitalism, security and domination, we maintain that solutions to climate change that rely on making war, securitizing and commoditizing are likely to only exacerbate and extend the negative impacts of anthropogenic climate change. As such, this article proposes that peacemaking and liberation be integrated into human-environment interaction(s) by calling for the rejection of a "war on climate change" and by suggesting what a "peace treaty with the earth" would look like