The Kuiper Belt and Other Debris Disks

We discuss the current knowledge of the Solar system, focusing on bodies in the outer regions, on the information they provide concerning Solar system formation, and on the possible relationships that may exist between our system and the debris disks of other stars. Beyond the domains of the Terrestrial and giant planets, the comets in the Kuiper belt and the Oort cloud preserve some of our most pristine materials. The Kuiper belt, in particular, is a collisional dust source and a scientific bridge to the dusty "debris disks" observed around many nearby main-sequence stars. Study of the Solar system provides a level of detail that we cannot discern in the distant disks while observations of the disks may help to set the Solar system in proper context.Comment: 50 pages, 25 Figures. To appear in conference proceedings book "Astrophysics in the Next Decade

Lysyl oxidase ( Lox ) maps between Grl-1 and Adrb-2 on mouse Chromosome 18

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47002/1/335_2004_Article_BF00352234.pd

The Physics of Star Cluster Formation and Evolution

© 2020 Springer-Verlag. The final publication is available at Springer via https://doi.org/10.1007/s11214-020-00689-4.Star clusters form in dense, hierarchically collapsing gas clouds. Bulk kinetic energy is transformed to turbulence with stars forming from cores fed by filaments. In the most compact regions, stellar feedback is least effective in removing the gas and stars may form very efficiently. These are also the regions where, in high-mass clusters, ejecta from some kind of high-mass stars are effectively captured during the formation phase of some of the low mass stars and effectively channeled into the latter to form multiple populations. Star formation epochs in star clusters are generally set by gas flows that determine the abundance of gas in the cluster. We argue that there is likely only one star formation epoch after which clusters remain essentially clear of gas by cluster winds. Collisional dynamics is important in this phase leading to core collapse, expansion and eventual dispersion of every cluster. We review recent developments in the field with a focus on theoretical work.Peer reviewe

Mucolipidosis III. (Pseudo-Hurler polydystrophy) ultrastructure of conjunctival biopsies

Conjunctival biopsies of six patients with mucolipidosis III (pseudo-Hurler polydystrophy) were studied by light and electron microscopy. Pathologic changes were consistently evident only at the ultrastructural level and involved fibrillogranular material and few lamellar lipid inclusions within lysosomes of fibroblasts, capillary endothelial cells and occasional Schwann cells. The moderate and variable storage evident in these patients' tissues may be consistent with the concept of genetic heterogeneity in multiple lysosomal hydrolase deficiencies and with the hypothesis that mucolipidosis III represents the mild phenotype of I-cell disease.SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe

Retinal toxicity of intravitreal gentamicin: an electron microscopic study

info:eu-repo/semantics/publishe

Retinal toxicity of intravitreal aminoglycoside antibiotics: Differential susceptibility of the retinal pigment epithelium to drug toxicity

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Comparative toxicity of intravitreal aminoglycoside antibiotics

We compared the toxicity of the aminoglycoside antibiotics (tobramycin, amikacin, netilmicin, and kanamycin) by ophthalmoscopy, light and electron microscopy, and electroretinography after intravitreal injection in rabbits in doses ranging from 100 to 3,000 μg. The earliest manifestations of toxicity were confined to the outer retina with each drug, with lamellar lysosomal inclusions in the retinal pigment epithelium as the earliest finding. However, the aminoglycosides displayed marked differences in the threshold dose required to produce toxic reactions, permitting the following ordering of toxicity: (most toxic) gentamicin > netilmicin = tobramycin > amikacin = kanamycin (least toxic). © 1985.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Retinal toxicity of intravitreal aminoglycoside antibiotics: Differential susceptibility of RPE to drug toxicity

info:eu-repo/semantics/nonPublishe

Retinal toxicity of intravitreal aminoglycoside antibiotics: Differential susceptibility of RPE to drug toxicity

info:eu-repo/semantics/publishe