40 research outputs found
Relationship of Circulating Ghrelin and Leptin Concentrations in Beef Cattle ExhibitingDifferences in Composition of Gain
Beef steers (n = 72) of similar age, weight (651 ± 3.1 lb), and genetic background (Angus crossbred) were used to determine the effects of growing period diet on the relationship of plasma ghrelin and leptin concentrations with growth performance and carcass composition. At trial initiation (d 0), 8 steers were harvested for initial carcass composition. The remaining 64 steers were allotted, by weight, to pen and treatment was assigned randomly. Treatments were 1) a high‐forage diet fed during the growing period (0‐116 d) followed by a high‐concentrate diet during the finishing period (117‐209 d; GRW‐FNSH) or 2) a high‐concentrate diet fed for the duration of the trial (0‐209 d; FNSH‐FNSH). Steers were allowed ad libitum consumption regardless of dietary treatment. Eight steers per treatment (1 pen) were harvested on d 88, 116, 165, and 209. At each harvest date, 9‐10‐11th rib sections were dissected for chemical composition, and carcass characteristics were recorded. Replicate blood samples were collected from every steer prior to each harvest, and assayed for ghrelin, leptin, GH, insulin, and NEFA concentrations. Hormone, growth performance, and carcass composition were analyzed statistically using the GLM procedure of SAS to evaluate diet, harvest date, and their interaction. Linear, quadratic, and cubic contrasts were performed. Percent carcass protein decreased linearly (P \u3c 0.001) and percent carcass fat increased linearly (P \u3c 0.001) in both treatments. At each harvest day, FNSH‐FNSH steers had greater carcass fat (P \u3c 0.01) compared with GRW‐FNSH steers. Plasma ghrelin concentrations for FNSH‐FNSH increased quadraticly (P \u3c 0.001) over time, whereas plasma ghrelin concentrations were not different over time for GRW‐FNSH. Plasma leptin concentrations for FNSH‐FNSH increased (P \u3c 0.001) from d 0 to 88 and then plateaued, whereas plasma leptin concentrations increased linearly (P \u3c 0.001) for the GRW‐FNSH. Plasma ghrelin and leptin concentrations fluctuated relative to nutritional status, and plasma ghrelin concentrations were highest in excessively fat cattle. The role of ghrelin during fat accumulation warrants further investigation
Post-weaning Nutritional Programming of Ovarian Developmentin Beef Heifers
The nutritional management of replacement females from weaning to breeding is critical to lifetime productivity. Traditionally, cereal grains have been used to develop replacement heifers to attain puberty and enter the breeding system at a younger age. However, overfeeding heifers decreases number of calves weaned, while peri-pubertal caloric restriction increased primordial follicle numbers in the developing ovary. The number of primordial follicles a female has can determine her overall fertility; females with a greater amount of follicles have greater reproductive lifespans. In this study, two groups of heifers were developed to prebreeding status. One group received a control diet (228 kcal ME/BW kg0.75) while the other received a restricted diet (157 kcal ME/BW kg0.75) for 84 days, and were then stepped up to receive a diet containing 277 kcal ME/BW kg0.75. Both groups were evaluated at three different time points for number of primordial follicles. Heifers on the restricted diet had more primordial follicles than control heifers at 13 mo of age. In summary, heifer input costs could be decreased without negatively effecting overall fertility and perhaps improve fertility
Running Spectral Index and Formation of Primordial Black Hole in Single Field Inflation Models
A broad range of single field models of inflation are analyzed in light of
all relevant recent cosmological data, checking whether they can lead to the
formation of long-lived Primordial Black Holes (PBHs). To that end we calculate
the spectral index of the power spectrum of primordial perturbations as well as
its first and second derivatives. PBH formation is possible only if the
spectral index increases significantly at small scales, i.e. large wave number
. Since current data indicate that the first derivative of the
spectral index is negative at the pivot scale , PBH formation
is only possible in the presence of a sizable and positive second derivative
("running of the running") . Among the three small-field and five
large-field models we analyze, only one small-field model, the "running mass"
model, allows PBH formation, for a narrow range of parameters. We also note
that none of the models we analyze can accord for a large and negative value of
, which is weakly preferred by current data.Comment: 26 pages, 5 figures, Refs. added, Minor textual change; version to
appear in JCA
Non-Gaussian isocurvature perturbations in dark radiation
We study non-Gaussian properties of the isocurvature perturbations in the
dark radiation, which consists of the active neutrinos and extra light species,
if exist. We first derive expressions for the bispectra of primordial
perturbations which are mixtures of curvature and dark radiation isocurvature
perturbations. We also discuss CMB bispectra produced in our model and forecast
CMB constraints on the nonlinearity parameters based on the Fisher matrix
analysis. Some concrete particle physics motivated models are presented in
which large isocurvature perturbations in extra light species and/or the
neutrino density isocurvature perturbations as well as their non-Gaussianities
may be generated. Thus detections of non-Gaussianity in the dark radiation
isocurvature perturbation will give us an opportunity to identify the origin of
extra light species and lepton asymmetry.Comment: 32 pages, 7 figure
Isocurvature perturbations in extra radiation
Recent cosmological observations, including measurements of the CMB
anisotropy and the primordial helium abundance, indicate the existence of an
extra radiation component in the Universe beyond the standard three neutrino
species. In this paper we explore the possibility that the extra radiation has
isocurvatrue fluctuations. A general formalism to evaluate isocurvature
perturbations in the extra radiation is provided in the mixed inflaton-curvaton
system, where the extra radiation is produced by the decay of both scalar
fields. We also derive constraints on the abundance of the extra radiation and
the amount of its isocurvature perturbation. Current observational data favors
the existence of an extra radiation component, but does not indicate its having
isocurvature perturbation. These constraints are applied to some particle
physics motivated models. If future observations detect isocurvature
perturbations in the extra radiation, it will give us a hint to the origin of
the extra radiation.Comment: 41 pages, 8 figures; version accepted for publication in JCA
Issues Concerning Loop Corrections to the Primordial Power Spectra
We expound ten principles in an attempt to clarify the debate over infrared
loop corrections to the primordial scalar and tensor power spectra from
inflation. Among other things we note that existing proposals for nonlinear
extensions of the scalar fluctuation field introduce new ultraviolet
divergences which no one understands how to renormalize. Loop corrections and
higher correlators of these putative observables would also be enhanced by
inverse powers of the slow roll parameter . We propose an extension
which should be better behaved.Comment: 36 pages, uses LaTeX2e, version 3 revised for publication with a much
expanded section 4, proving that our proposed extension of the zeta-zeta
correlator absorbs the one loop infrared divergences from graviton