17 research outputs found
Synthesis and Biological Activity of N-Sulfonyltripeptides with C-Terminal Arginine as Potential Serine Proteases Inhibitors
House dust mites known to be an allergen source for 50 years: Der p 1 still detectable in the original sample
Prevalence of the group 1 Dermatophagoides allergens Der p 1 and Der f 1 in homes with no dogs, healthy dogs and Dermatophagoides-sensitized atopic dogs in Liverpool
Sensitization to house dust mites in Reykjavik, Iceland, in the absence of domestic exposure to mites
Effects of Tripeptides on the Amidolytic Activities of Urokinase, Thrombin, Plasmin and Trypsin
House dust and forage mite allergens and their role in human and canine atopic dermatitis
This article reviews the literature regarding the role of house dust and forage mite allergens in canine atopic dermatitis. The presence of immunoglobulin E (IgE) to these mites, especially to Dermatophagoides farinae, is common in both normal and atopic dogs. Exposure of dogs to the different mites is described both in the direct environment and in the coat of animals for house dust mites and in the food for forage mites. Allergens causing allergic disease in dogs seem to be different from those in humans. Dogs seem to react to high molecular weight allergens, compared to the low molecular weight group 1 and group 2 proteases that are commonly implicated in humans with atopic diseases. Despite numerous published studies dealing with this subject, a number of questions still need to be addressed to better understand the exact role of these mites in the pathogenesis of canine atopic dermatitis and to improve the quality of the allergens used in practice.T. J. Nuttall, Peter B. Hill, E. Bensignor, T. Willemse and the members of the International Task Force on Canine Atopic Dermatiti