Correlation between lung neoplasm and serum level of osteopontin: A meta-analysis

Abstract. The aim of this meta?analysis was to evaluate the clinical significance of serum osteopontin (OPN) levels inlung neoplasm in patients to establish a novel diagnostic score model. Articles were identified by searching the PubMed,Web of Science, Google Scholar, China National Knowledge Infrastructure, and Wang Fang databases. Studies identifiedwere pooled, and the standardized mean difference (SMD) and its corresponding 95% confidence interval (CI) werecalculated. Subgroup analyses and publication bias detection were also conducted. Version 12.0 STATA software wasused for statistical analysis. A final analysis of 1,327 subjects together (740 patients with lung neoplasms and 587 controls)was performed from 10 clinical case?control studies. The meta?analysis results showed a positive association betweenserum OPN levels and lung neoplasm (SMD=5.59, 95% CI: 1.85?3.32,

Non-Noble Metal High-Entropy Alloy-Based Catalytic Electrode for Long-Life Hydrogen Gas Batteries

The development of efficient, stable, and low-cost bifunctional catalysts for the hydrogen evolution/oxidation reaction (HER/HOR) is critical to promote the application of hydrogen gas batteries in large scale energy storage systems. Here we demonstrate a non-noble metal high-entropy alloy grown on Cu foam (NNM-HEA@CF) as a self-supported catalytic electrode for nickel-hydrogen gas (Ni-H2) batteries. Experimental and theoretical calculation results reveal that the NNM-HEA catalyst greatly facilitates the HER/HOR catalytic process through the optimized electronic structures of the active sites. The assembled Ni-H2 battery with NNM-HEA@CF as the anode shows excellent rate capability and exceptional cycling performance of over 1800 h without capacity decay at an areal capacity of 15 mAh cm–2. Furthermore, a scaled-up Ni-H2 battery fabricated with an extended capacity of 0.45 Ah exhibits a high cell-level energy density of ∼109.3 Wh kg–1. Moreover, its estimated cost reaches as low as ∼107.8 $ kWh–1 based on all key components of electrodes, separator and electrolyte, which is reduced by more than 6 times compared to that of the commercial Pt/C-based Ni-H2 battery. This work provides an approach to develop high-efficiency non-noble metal-based bifunctional catalysts for hydrogen batteries in large-scale energy storage applications