Unveiling the nucleon tensor charge at Jefferson Lab: A study of the SoLID case

Future experiments at the Jefferson Lab 12 GeV upgrade, in particular, the Solenoidal Large Intensity Device (SoLID), aim at a very precise data set in the region where the partonic structure of the nucleon is dominated by the valence quarks. One of the main goals is to constrain the quark transversity distributions. We apply recent theoretical advances of the global QCD extraction of the transversity distributions to study the impact of future experimental data from the SoLID experiments. Especially, we develop a simple strategy based on the Hessian matrix analysis that allows one to estimate the uncertainties of the transversity quark distributions and their tensor charges extracted from SoLID data simulation. We find that the SoLID measurements with the proton and the effective neutron targets can improve the precision of the u- and d-quark transversity distributions up to one order of magnitude in the range 0.05 < x < 0.6.Comment: 11 pages, 3 figures, published on Physics Letters

Anti-aging effect of hydrocolloid on tartary buckwheat parfaith

The effects of mono-hydrophilic colloid(xanthan gum,guar gum,sodium alginate,hydroxypropyl methylcellulose and carrageenan) on the anti-aging of tartary buckwheat parfait were studied with sensory evaluation and hardness as indexes,and three kinds of hydrophilic colloid with better anti-aging effect were screened out.Based on this,the optimal anti-aging agent of tartary buckwheat parfait was determined by response surface analysis method.The results showed that the optimal anti-aging agent formula was 0.13%of xanthan gum,0.17% of sodium alginate and 0.24% of carrageenan(calculated bytotal slurryweight).The storage time of tartary buckwheat parfait with compound hydrophilic colloids was prolonged by 2 times(14 days)of that without hydrocolloid the at-4 ℃

The latest application and research progress of Glycemic Index

Glycemic Index, proposed by Dr.Jekins in 1970, was an index that measured blood sugar capacity of food. Recent research indicated that glycemic index had positive effects on therapy of diabetic patients and weight management for the overweight. In this paper, the author introduced the concept of glycemic index, food materials grading based on GI, the relationships between GI and food components, the physiological reaction of human separately consuming high GI or low GI food, the application of GI in prevention and cure of diabetes. The review will provided scientific evidences for medical treatment and designing nutritional meal for diabetic patients in comtemporary medical science

The Influence of Secondary Extrusion Process on The Quality of Instant Rice Noodle

In order to study the influence of the two-stage extrusion process on the quality of instant rice noodle, the key parameters of the two-stage extrusion process including: the first and second stage extruder barrel temperature, the first and second stage extruder screw speed, feeding speed, and the template hole diameter were taken as the single factor research objects, and the single factor experiment and response surface experiment were used to optimize them. The results show that the optimization of extrusion parameters can improve the quality of instant rice noodle in a certain range. The final optimization of the two-stage extrusion process parameters are as follows: the first stage extruder barrel temperature was 173 ℃,the second stage extruder barrel temperature was 39 ℃, the first stage extruder screw speed was 30 Hz, the second stage extruder screw speed was 20 Hz, the feeding speed was 11.8hz, and the template aperture was 0.7 mm. Under this condition, the instant rice noodle product is made with Strong fragrance and good comprehensive quality which can reach market product quality. This study can provide a reference for the continuous production of instant rice noodle

Progress in key technologies for traceability of rice industry chain

As one of the main food crops in the world, the rice quality and safety situation is not optimistic, the development of rice traceability system has become a hot topic at home and abroad. This paper summarizes the research status of rice traceability technology from two aspects including the origin diagnosis technology (such as: physical index fingerprint technology, stable isotope technology, multi-element analysis technology, near-infrared spectroscopy technology) and the traceability system technology (such as: physical identification technology, information coding technology, information transmission technology). Based on this analysis, the development trend of rice traceability system was analyzed, and new technologies will continue to be applied to the traceability system

Luspatercept Enhances Hemoglobin Levels in a Chinese Boy With Congenital Sideroblastic Anemia: A Case Report

BACKGROUND: Congenital sideroblastic anemia (CSA) is a rare and heterogeneous group of genetic disorders. Conventional treatment include pyridoxine (vitamin B6) and allogeneic hematopoietic stem cell transplantation (allo-HSCT), and can alleviate anemia in the majority of cases. Nevertheless, some CSA cases remain unresponsive to pyridoxine or are unable to undergo allo-HSCT. Novel management approaches is necessary to be developed. To explore the response of luspatercept in treating congenital sideroblastic anemia. CASE SUMMARY: We share our experience in luspatercept in a 4-year-old male patient with CSA. Luspatercept was administered subcutaneously at doses of 1.0 mg/kg/dose to 1.25 mg/kg/dose every 3 wk, three consecutive doses, evaluating the hematological response. Luspatercept leading to a significant improvement in the patient\u27s anemia. The median hemoglobin during the overall treatment with three doses of luspatercept was 90 (75-101) g/L, the median absolute reticulocyte count was 0.0593 (0.0277-0.1030) × 10 CONCLUSION: We believe that luspatercept might emerge as a viable therapeutic option for the maintenance treatment of CSA or as a bridging treatment option before hematopoietic stem cell transplantation

Pure curcumin decreases the expression of WT1 by upregulation of miR-15a and miR-16-1 in leukemic cells

<p>Abstract</p> <p>Background</p> <p>Pure curcumin has been reported to down-regulate the expression of WT1 in leukemic cells. However, the molecular mechanism underlying the down-regulation of WT1 by curcumin is not completely delineated. The purpose of this present study is to identify a new miRNA-mediated mechanism which plays an important role in the anti-proliferation effects of curcumin in leukemic cells.</p> <p>Methods</p> <p>K562 and HL-60 cells were treated with different concentrations of curcumin for 24 and 48 hours, the level of miR-15a/16-1 and WT1 were detected by qRT-PCR and Western blotting. WT1 expression and cell proliferation were detected by Western blotting and CCK-8, after curcumin treated-K562 and HL-60 cells were transfected with anti-miR-15a/16-1 oligonucleotides.</p> <p>Results</p> <p>We found that pure curcumin upregulated the expression of miR-15a/16-1 and downregulated the expression of WT1 in leukemic cells and primary acute myeloid leukemia (AML) cells. Overexpression of miR-15a/16-1 deduced the protein level of WT1 in leukemic cells, but downregulation of WT1 by siRNA-WT1 could not increase the expression of miR-15a/16-1 in leukemic cells. These results reveal that curcumin induced-upregulation of miR-15a/16-1 is an early event upstream to downregulation of WT1. Furthermore, anti-miR-15a/16-1 oligonucleotides (AMO) partly reversed the downregulation of WT1 induced by pure curcumin in leukemic cells and AMO promoted the growth of curcumin treated-K562 and HL-60 cells.</p> <p>Conclusion</p> <p>Thus, these data suggest for the first time that pure curcumin downregulated the expression of WT1 partly by upregulating the expression of miR-15a/16-1 in leukemic cells. miR-15a/16-1 mediated WT1 downregulation plays an important role in the anti-proliferation effect of curcumin in leukemic cells.</p