CLINICAL AND BIOCHEMICAL STUDIES ON THE BASIS OF KETONE BODIES IN CATTLE : II. URINE KETONE BODIES IN NORMAL DAIRY CATTLE

These clinical and biochemical studies were made on the basis of the urine ketone bodies in 368 clinically healthy dairy cows. The results thus obtained may be summarized as follows. 1. The values for the urine ketone bodies of the clinically healthy cows varied so widely that they were statistically divided into 2 groups, viz., "normal and sub-normal groups". 2. The mean values for the ketone bodies of the normal group were 6.19 (2.12〜43.41) mg/100 ml in total ketone, and 1.25 (0.18〜24.95) mg/100 ml in free acetone. 3. The mean values for the ketone bodies of the sub-normal group were 122.50 (47.97〜258.00) mg/100 ml in total ketone, and 54.50 (25.83〜123.00) mg/100 ml in free acetone. 4 The values for free acetone, acetoacetic acid and β-hydroxybutyric acid increased in accordance with the increase of the total ketone. 5. All of the internal and external factors exerted influence upon the rise and fall of the total ketone, especially the stress of parturition, milk yield, season and feeding-management are very important. 6. The strength of the sugar and urobilinogen reaction in urine runs in parallel with the increase of the urine ketones. 7. In the sub-norml group, not only the increase of the ketone bodies but also increase of the blood sugar level and marked decrease in number of eosinophilic leucocytes were clarified

CLINICAL AND BIOCHEMICAL STUDIES ON THE BASIS OF KETONE BODIES IN CATTLE : I. BLOOD KETONE BODIES IN NORMAL DAIRY CATTLE

These clinical and biochemical studies were made on the basis of the blood ketone bodies in 368 clinically healthy dairy cows. The result thus obtained may be summarized as follows. 1. The values for the blood ketone bodies of the clinically healthy cows varied so widely that they were statistically divided into 2 groups, viz., "normal and sub-normal groups." 2. The mean values for the ketone bodies of the normal group were 3.11 (0.99〜11.17)mg/100ml in total ketone, and 0.79 (0.22〜4.53)mg/100ml in free acetone. 3. The mean values for the ketone bodies of the sub-normal group were 39.10 (12.30〜73.80)mg/100ml in total ketone, and 8.23 (5.20〜10.50)mg/100ml in free acetone. 4. The values for free acetone, acetoacetic acid and β-hydroxybutyric acid increased in accordance with the increase of the total ketone. 5. All of the internal and external factors exerted influence upon the rise and fall of the total ketone, especially, it may be supposed that the stress of parturition, milk yield, season and feeding-management were very important. 6. It was clarified that the sub-normal group showed not only the increase of the ketone bodies but also increase of the blood sugar level and marked decrease in number of eosinophilic leucocytes