Infection By Cytomegalovirus In Patients With Neonatal Cholestasis

Background - Neonatal cholestasis syndrome with an intra or extrahepatic origin has been associated to viral infections. The participation of the cytomegalovirus in the etiopathogenesis of neonatal hepatitis has been already known for some time, but only recently there have been indications that this virus may be one of the possible etiological factors for extrahepatic biliary atresia. Aims - To assess the prevalence of infection by cytomegalovirus in patients with intrahepatic cholestasis and extrahepatic cholestasis. To compare the clinical characteristics of the intrahepatic cholestasis and extrahepatic cholestasis groups with the cytomegalovirus serological results. Patients and Methods - This study consisted of 76 patients with neonatal cholestasis who were admitted between January 1980 and January 1999 when they underwent a cytomegalovirus serologic study using the ELISA method. A case note was kept on each patient with the following data: age of patient at admission, serologic result for cytomegalovirus, history of maternal infection, prematurity, fetal distress, birth weight, ponderal gain, choluria and fecal acholia. The final anatomic diagnosis of cholestasis was based on the results of an abdominal ultrasonography, a liver biopsy and its evolution. The patients were then divided into two groups: group I - intrahepatic cholestasis and group II - extrahepatic cholestasis. Each of these groups were then divided into two subgroups: subgroup A - positive serology (IgM) for cytomegalovirus and subgroup B - negative serology (IgM) for cytomegalovirus. Results - The frequency of positive serology (IgM) for cytomegalovirus was 29.4% in children with intrahepatic cholestasis and 28.5% in children with extrahepatic cholestasis. In comparison with group IIB, group IIA presented a higher rate of maternal infection history. The patients in group IIA demonstrated a delayed access to the service in comparison with group IA. The groups did not demonstrate any significant differences regarding the onset age of jaundice, choluria and fecal acholia, birth weight and ponderal gain. Conclusions - The positive (IgM) seroprevalence for cytomegalovirus in children with intrahepatic cholestasis and extrahepatic cholestasis is high. The history of maternal infection was more common in extrahepatic cholestasis patients with positive serology for cytomegalovirus. 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Cross-Cultural Comparison of Company Organization Structure

This study tends to quantify some differences of developed and developing countries in the field of human resources. Due to different social and cultural milieus, no global solution is available to fit each country. This fact necessitates a special examination for countries according to their cultural context. In this part of the study, the cultural and social influential elements of the working force in a developing country were examined. The specific elements of satisfaction and production driving force with accordance with the motivation factors were defined. Variables that are most associated with individual performance, behavior and social structure that govern the inter-personnel relations were specified

Productivity and cost analysis of semi-mechanised and mechanised systems on the Viphya forest plantations in Malawi

At least 200 000 m3 of timber is harvested annually using semi-mechanised harvesting systems on the Viphya forest plantations in Malawi. Although these systems have long been used on the Viphya, no investigation on their productivity has so far been reported. Additionally, the absence of localised productivity analyses in Malawi has created a paucity of information on appropriate timber harvesting systems for production maximisation and cost minimisation. The objective of this study was to compare the production rates and operational costs of chainsaw/grapple skidder (semi-mechanised) and feller-buncher/grapple skidder (mechanised) harvesting systems in order to determine the economic feasibility of mechanised systems in the Viphya forest plantations. The study was conducted in Pinus kesiya compartments at the Kalungulu and Champhoyo forest stations of the Viphya forest plantations. A work study approach was followed to capture harvesting time and volume data for the semi-mechanised system. Secondary work study data were used to simulate productivity of the mechanised system on similar compartment conditions. A timber-harvesting costing model was used to analyse the results. The study showed that the simulated mechanised system was associated with lower operating costs and inventories with higher production rates than the semi-mechanised system. The cost marginal difference was US$0.89 m−3. It was therefore established that migration to mechanised systems could optimise timber harvesting productivity on the Viphya in future, if optimal volumes are available to ensure the efficient application of the mechanised harvesting system.Mzuzu University and the SAFCOL Forest Chair of University of Pretoria, Barloworld Equipment (Isando) and John Deere (Nelspruit)http://www.tandfonline.com/loi/tsfs202015-08-30hb201