Antiplasmodial and larvicidal flavonoids from Derris trifoliata

From the dichloromethane-methanol (1:1) extract of the seed pods of Derris trifoliata, a new flavanone derivative (S)-lupinifolin 4´-methyl ether was isolated. In addition, the known flavonoids lupinifolin and rotenone were identified. The structures were determined on the basis of spectroscopic evidence. Lupinfolin showed moderate in vitro antiplasmodial activity against the D6 (chloroquine-sensitive) and W2 (chloroquineresistant)strains of Plasmodium falciparum. The different parts of this plant showed larvicidal activities against Aedes aegypti and rotenoids were identified as the active principles

Insecticidal activity of extracts derived from different parts of the mangrove tree rhizophora mucronata (rhizophoraceae) lam. Against three arthropods

The insecticidal and antifeedant activity of extracts derived from different parts of the mangrove tree Rhizophora mucronata (Rhizophoraceae) Lam. is reported. The 70% ethanol extracts of leaves, bark, stem wood and pith were tested for toxicity against adults of the desert locust Schistocerca gregaria (Forskal), the 2nd instar larvae of Aedes aegypti (L.) and the 1st instar larvae of the brine shrimp Artemia salina (Leach). Antifeedant activity of the extracts was assessed through tests conducted on S. gregaria adults by the paper feeding protection bioassay. In tests carried out on A. aegypti mosquito larvae, bark and pith extracts showed high toxicity with 48 hour LC50’s of 157.4 ppm and 168.3 ppm respectively. Stem wood extracts had low activity with an LC50 of 1003.4 ppm while leaf extracts did not exhibit toxic effects at a concentration of 1000 ppm. A similar trend in activity was observed with antifeedant tests conducted on the desert locust S. gregaria and on toxicity tests carried out on A. salina larvae. The bulk of the active compounds are sequestered in the bark, pith and stem wood with the least being found in the leaves. The results indicate that R.mucronata is a potential source of botanical insecticides(s)