10 research outputs found
Nanofibrous Poly(ε-Caprolactone)/Poly(Vinyl Alcohol)/Chitosan Hybrid Scaffolds for Bone Tissue Engineering using Mesenchymal Stem Cells
Osteogenic Differentiation of Human Bone Marrow Stromal Cells on Partially Demineralized Bone Scaffolds in Vitro
Article Commentary: Thoracolumbar Spine Trauma: Diagnostic and Therapeutic Considerations for the General Surgeon
Physicochemical properties and applications of poly(lactic-co-glycolic acid) for use in bone regeneration
Item does not contain fulltextPoly(lactic-co-glycolic acid) (PLGA) is the most often used synthetic polymer within the field of bone regeneration owing to its biocompatibility and biodegradability. As a consequence, a large number of medical devices comprising PLGA have been approved for clinical use in humans by the American Food and Drug Administration. As compared with the homopolymers of lactic acid poly(lactic acid) and poly(glycolic acid), the co-polymer PLGA is much more versatile with regard to the control over degradation rate. As a material for bone regeneration, the use of PLGA has been extensively studied for application and is included as either scaffolds, coatings, fibers, or micro- and nanospheres to meet various clinical requirements
Nanophase hydroxyapatite as a biomaterial in advanced hard tissue engineering: a review
Item does not contain fulltextHydroxyapatite is a biocompatible material that is extensively used in the replacement and regeneration of bone material. In nature, nanostructured hydroxyapatite is the main component present in hard body tissues. Hence, the state of the art in nanotechnology can be exploited to synthesize nanophase hydroxyapatite that has similar properties with natural hydroxyapatite. Sustainable methods to mass-produce synthetic hydroxyapatite nanoparticles are being developed to meet the increasing demand for these materials and to further develop the progress made in hard tissue regeneration, especially for orthopedic and dental applications. This article reviews the current developments in nanophase hydroxyapatite through various manufacturing techniques and modifications