Peliosis of the spleen: possible association with chronic renal failure and erythropoietin therapy.

Splenic peliosis was identified at necropsy in a 62-year-old woman receiving continuous ambulatory peritoneal dialysis for end-stage renal failure, and erythropoietin therapy for uraemia and anaemia. The immediate cause of death was arrhythmia related to ischaemic heart disease, following an episode of intramuscular haematoma (secondary to platelet dysfunction). The unusual association between peliosis and renal failure, and possibly erythropoietin therapy, is discussed

X-ray holography

With the dramatic increase in x-ray source brilliance and associated coherent photon flux, holography with x-rays has become feasible and is increasingly used for real-space investigations of static and dynamic properties of nanoscale systems. We describe the basic principles and capabilities of the method and present the current state of the art. A particular emphasis is put on the investigation of magnetic nanostructures, where x-ray holography has been applied at synchrotron radiation sources and free-electron x-ray lasers to investigate dynamic effects on time scales down to the femtosecond regime