9 research outputs found
Lack of stereospecificity in lysophosphatidic acid enantiomer-induced calcium mobilization in human erythroleukemia cells
Theia: an advanced optical neutrino detector
Š 2020, The Author(s). New developments in liquid scintillators, high-efficiency, fast photon detectors, and chromatic photon sorting have opened up the possibility for building a large-scale detector that can discriminate between Cherenkov and scintillation signals. Such a detector could reconstruct particle direction and species using Cherenkov light while also having the excellent energy resolution and low threshold of a scintillator detector. Situated deep underground, and utilizing new techniques in computing and reconstruction, this detector could achieve unprecedented levels of background rejection, enabling a rich physics program spanning topics in nuclear, high-energy, and astrophysics, and across a dynamic range from hundreds of keV to many GeV. The scientific program would include observations of low- and high-energy solar neutrinos, determination of neutrino mass ordering and measurement of the neutrino CP-violating phase δ, observations of diffuse supernova neutrinos and neutrinos from a supernova burst, sensitive searches for nucleon decay and, ultimately, a search for neutrinoless double beta decay, with sensitivity reaching the normal ordering regime of neutrino mass phase space. This paper describes Theia, a detector design that incorporates these new technologies in a practical and affordable way to accomplish the science goals described above11sci
Environmental drivers of increased ecosystem respiration in a warming tundra
Arctic and alpine tundra ecosystems are large reservoirs of organic carbon1,2. Climate warming may stimulate ecosystem respiration and release carbon into the atmosphere3,4. The magnitude and persistency of this stimulation and the environmental mechanisms that drive its variation remain uncertain5â7. This hampers the accuracy of global land carbonâclimate feedback projections7,8. Here we synthesize 136 datasets from 56 open-top chamber in situ warming experiments located at 28 arctic and alpine tundra sites which have been running for less than 1 year up to 25 years. We show that a mean rise of 1.4 °C [confidence interval (CI) 0.9â2.0 °C] in air and 0.4 °C [CI 0.2â0.7 °C] in soil temperature results in an increase in growing season ecosystem respiration by 30% [CI 22â38%] (n = 136). Our findings indicate that the stimulation of ecosystem respiration was due to increases in both plant-related and microbial respiration (n = 9) and continued for at least 25 years (n = 136). The magnitude of the warming effects on respiration was driven by variation in warming-induced changes in local soil conditions, that is, changes in total nitrogen concentration and pH and by context-dependent spatial variation in these conditions, in particular total nitrogen concentration and the carbon:nitrogen ratio. Tundra sites with stronger nitrogen limitations and sites in which warming had stimulated plant and microbial nutrient turnover seemed particularly sensitive in their respiration response to warming. The results highlight the importance of local soil conditions and warming-induced changes therein for future climatic impacts on respiration
May the weak force be with you: The power of the mass media in modern politics
The idea that the modern mass media have a strong and malign effect on many aspects of social and political life is widely and strongly held. Television is often said to undermine democratic government popular support for leaders and institutions. In spite of all that has been written about media malaise, however, both theory and evidence suggests that the media are a comparatively weak force whose effects can be deflected, diluted and diffused by stronger forces. These include bedrocks political values associated with class, religion, age, gender and education, as well as social networks and discussions, distrust of the mass media, and personal knowledge and experience. Equally, the variables that mediate the media may also magnify its effects so that what appears to be a large media effect is, in fact, the result of an interaction between the media and other forces. This article lays out the argument of the media malaise literature that covers government and politics, then outlines the social forces that mediate the media, and finally provides some evidence to illustrate the argument that the media are generally a weak force in society