11,612 research outputs found

    Common fixed point theorems of different compatible type mappings using Ciric\u27s contraction type condition

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    The purpose of this paper is to establish necessary and sufficient conditions for the existence of common fixed points for a compatible pair of selfmaps under Ciric\u27s contraction type condition. These theorems improve and generalize the results of Mukherjee and Verma [11] and Jungck [9] to a pair of selfmaps. Also established the existence of common fixed points for a pair of compatible mappings of type (B), and obtain a result on the existence of common fixed points for a pair of compatible mappings of type (A) as corollary. Greguš fixed point theorem follows as a special case to our results

    Novel phytosynthesis of nanoparticles using Indigeneous Australian Plants

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    Nanoparticles are considered to be the building blocks of nanotechnology. Biosynthesis of nanoparticles using plant material is an exciting and relatively new developing research area in nanobiotechnology. In the present study, Eucalyptus leaves were collected from Olive pink botanical garden, Alice Springs, Australia and were used to synthesize silver nanoparticles. Cubical structured and well monodispersed silver nanoparticles were formed with an average size of 50nm. The formed silver nanoparticles are found to have promising applications in medicine as good antimicrobial agents. To the best of our knowledge this is the first report on exploiting indigeneous Australian plant sources for the synthesis of metallic nanoparticles

    Characteristics of superplasticity domain in the processing map for hot working of as-cast Mg–11.5Li-1.5Al alloy

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    Processing map for hot working of as-cast Mg-11.5Li-1.5Al alloy has been developed in the temperature range 200–450°C and strain rate range 0.001-100 s−1. The map exhibited a single domain with a peak efficiency of 65% occurring at 400°C and 0.001 s−1. Under these conditions, the material exhibited abnormal elongation. On the basis of the elongation, the grain structure, the apparent activation energy for hot deformation (95 kJ mole−1) and the peak efficiency of power dissipation (65% corresponding to a strain rate sensitivity of about 0.5), the domain is interpreted to represent superplasticity. At strain rates higher than about 10 s−1, the material exhibits microstructural instability, while at temperatures of 450°C and a strain rate of 0.001 s−1, grain boundary cracking is observed

    Rock Magnetic properties of Proterozoic mafic dykes from the Southern margin of Cuddapah Basin

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    Seventeen basic dykes of Proterozoic age intruding the Archaean basement from the Southern margin of the Cuddapah Basin were studied from five sites for their magnetic characters. NRM intensity (Jn) of the dykes range between 1793 and 57×10−3 Am−1 while magnetic susceptibility (χ) ranges from 31 to 303×10−6 CGS units. Koenigsberger's ratio (Qn) varies from 1 to 55 for most of the specimens. All the above parameters are indicative of retaining the original magnetization in most of the dykes sampled. Based on the above mentioned rock magnetic properties along with hysterisis studies and low temperature (−196°C) magnetic studies, it is inferred that the main magnetic carrier in these dykes is magnetite in multi domain and mixed domain states. Dykes from Tirupati area seems to be magnetically altered

    Effect of phospholipase A on the structure and functions of membrane vesicles from Mycobacterium phlei

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    The phospholipid composition of the electron transport particles and coupling factor-depleted electron transport particles of Mycobacterium phlei are the same, but they differ in contents. The accessibility of partially purified phospholipase A to these membrane phospholipids was found to be different. Treatment of membranes of Mycobacterium phlei with phospholipase A impairs the rate of oxidation as well as phosphorylation. The inhibition of phosphorylation can be reversed by washing the membranes with defatted bovine serum albumin. The reconstitution of membrane-bound coupling factor-latent ATPase activity to phospholipase A-treated depleted electron transport particles and their capacity to couple phosphorylation to oxidation of substrates remained unaffected after phospholipase A treatment. However, the pH gradient as measured by bromthymol blue was not restored after reconstitution of phospholipase A-treated depleted electron transport particles with membrane-bound coupling factor-latent ATPase. These findings show that the phosphorylation coupled to the oxidation of substrates can take place without a pronounced pH gradient in these membrane vesicles. The dye 1-anilino-8-naphthalene sulfonic acid (ANS) exhibited low levels of energized and nonenergized fluorescence in phospholipase A-treated membranes. This decrease in the level of ANS fluorescence in phospholipase A-treated membranes was found to be directly related to the amount of phospholipids cleaved. The decrease in the energy-dependent ANS response in phospholipase A-treated electron transport particles, as compared with untreated electron transport particles, was shown to be a result of a change in the apparent Kd of the dye-membrane complex, and of a decrease in the number of irreversible or slowly reversible binding sites, with no change in the relative quantum efficiency of the dye. The decrease in ANS fluorescence in phospholipase A-treated particles appears to be due to a decrease in the hydrophobicity of the membranes

    A descriptive study of the prevalence of hypothyroidism among antenatal women and foetal outcome in treated hypothyroid women

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    Background:The objective of the study was to find out the prevalence of hypothyroidism among pregnant women and to study the foetal outcome in antenatal mothers in whom treatment was initiated early in pregnancy.Methods:This was a descriptive study conducted in the department of OBG Sree Gokulam Medical College, Venjaramoodu, Trivandrum from April 2013 to Oct 2014. 500 antenatal women coming for routine antenatal check up in the first trimester to antenatal OP were screened for hypothyroidism.TSH(thyroid stimulating hormone) was done in the first trimester and the prevalence of hypothyroidism was estimated. Patients were diagnosed as having subclinical or overt hypothyroidism based on the FT3 (free T3) and FT4 (free T4) results. Patients detected with hypothyroidism –both subclinical and overt were started on appropriate dose of L-thyroxin depending on her gestational age, body weight and level of TSH. Every 6weeks TSH levels were estimated and the dose of the drug adjusted. All these patients were followed up for their foetal outcome such as intrauterine demise, hyperbilirubinemia, prematurity, stillbirths and neonatal hypothyroidism.Results: In the present study, the prevalence of hypothyroidism was 5.6% of which 4% were having subclinical and 1.6% was having overt hypothyroidism. No significant difference in foetal complications, perinatal mortality and morbidity was noted between hypothyroid and euthyroid women.Conclusions:TSH testing should be included in routine antenatal investigations for early detection of subclinical and overt hypothyroidism among antenatal women and early treatment should be initiated so as to prevent complications.1.       Akhter SN, Tarannum R, Kabir MS. Pregnancy in overt and subclinical hypothyroidism and its fetomaternal outcome. Med Today. 2014;25(2). 2.       Sahu MT, Das V, Mittal S, Aggarwal A, Sahu M. overt and subclinical hypothyroid dysfunction among Indian pregnant women and its effect on maternal and foetal outcome. Arch Gynecol Obstet. 2010;281(2):215-20.3.       Ajmani SN, Aggarwal D, Bhatia P, Sharma M, Sarabhai V, Paul M. Prevalence of overt and subclinical thyroid dysfunction among pregnant women and its effect on maternal and foetal outcome. J Obstet Gynecol India. 2014;64(2):105-10.4.       Nirmala CV. Maternal outcome of hypothyroidism in pregnancy- a south Indian perspective. Am J Clin Med Res. 2014;2(2):47-50.5.       Goel P, Radotra A, Devi K, Malhotra S, Aggarwal A, Huria A. Maternal and perinatal outcome in pregnancy with hypothyroidism. Indian J Med Sci. 2005;59 (3):116-7.6.       Cleary-Goldman J, Malone FD, Lambert-Messerlain G, Sullivan L, Canick J, Porter TF, et al. Maternal thyroid hypo function and pregnancy outcome. Obstet Gynecol. 2008;112(1):85-92.7.       Casey BM, Dashe JS, Wells CE, McIntre DD, Byrd W, Leveno KJ, et al. Subclinical hypothyroidism and pregnancy outcomes. Obstet Gynecol. 2005;105(2):239-45.8.       Allan WC, Haddow JE, Palomaki GE, Williams J R, Mitchell ML, Hermos RJ, et al. Maternal thyroid deficiency and pregnancy complications implications for population screening. J Med Screen. 2000;7(3):127-30.9.       Stagnaro-Green A, Abalovich M, Alexander E, Azizi F, Mestman J, Negro R, et al. Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum. Thyroid Off J Am Thyroid Association. 2011;21(10):1081-125.10.    Cite this article as: Prasad DR, Nair NV, Deepika K.A descriptive study of the prevalence of hypothyroidism among antenatal women and foetal outcome in treated hypothyroid women.Int J Reprod Contracept Obstet Gynecol 2016;5:1892-6. Basnet P, Aggarwal N, Suri V, Dutta P, Mukhopadhyay K. Comparison of Maternal and perinatal outcome in pregnant women with hypothyroidism diagnosed before conception with hypothyroidism diagnosed during pregnancy Univers Coll Med Sci. 2014;2(2)

    Different mechanisms of energy coupling for transport of various amino acids in cells of Mycobacterium phlei

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    Whole cells of Mycobacterium phlei were shown to actively accumulate proline, leucine, lysine, tryptophan, histidine, glutamine, and glutamic acid to different steady state levels. The transport of proline, in contrast to that of other amino acids, was found to be insensitive to various respiratory inhibitors, e.g. cyanide, arsenate, azide, and sulfhydryl reagents. However, oxygen was an obligatory requirement for the uptake of proline, as well as for the other amino acids. The results indicate that the energy requirements for proline uptake are different from those of other amino acids. In contrast to the system from Escherichia coli, the mode of energy transduction for the uptake of proline, glutamine, and glutamic acid is different even though these amino acids are shock resistant in the M. phlei system

    ANTIOXIDANT AND ANTIULCER POTENTIAL OF ETHANOLIC EXTRACT OF BARK OF MYRICA ESCULENTA IN PYLORIC LIGATION ULCER MODEL

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    Objective: To evaluate the antiulcer and antioxidant potential of ethanolic extract of bark of Myrica esculenta in pyloric ligated ulcer model in albino rats.Methods: The rats were subjected to pyloric ligation ulcer model and the ethanolic extract of bark of Myrica esculenta were compared with the induced and standard drug Ranitidine. The activity of antioxidant parameters was analysed in the homogenate of stomachs.Results: The levels of gastric volume, total acidity, free acidity, lipid peroxidation and glutathione (GSH) were reduced significantly and antioxidant, parameters like catalase, nitrite and myeloperoxidase (MPO) were increased significantly in the ethanloic extract of bark of Myrica esculenta. Conclusion: The present study revealed that the ethanolic extract of bark of Myrica esculenta improved the anti ulcer and antioxidant potential. Â
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