Delayed presentation of primary parenchymal arachnoid cyst in adult population: a rare location of a common cyst—case report and review of the literature

Abstract Background Arachnoid cysts account for about 1% of all intracranial mass lesions. Intraparenchymal arachnoid cysts are an uncommon entity. Only a few reports are available in adults with the intraparenchymal arachnoid cyst. Case presentation We present a 40-year-old lady with right-side progressive hemiparesis, and radiology revealed a cystic mass located in the left posterior frontal area. She underwent craniotomy and excision of the cyst. In the postoperative period, she recovered well. Immunohistochemistry stains confirm arachnoid cyst. Conclusion This was a case of a pure frontal arachnoid cyst with delayed clinical presentation without any communication with sub-arachnoid space or ventricle

Supratentorial Pure Cortical Ependymoma: An Unusual Lesion Causing Focal Motor Aware Seizure

Ependymomas usually arise from the ependymal lining cells of the ventricular system and central canal of the spinal cord. Supratentorial ependymoma is a rare entity with the variable clinical course. In a small number of cases, ependymoma arises from supratentorial parenchyma. Only a few cases are reported in the literature. We report a case of 3-year-old girl with left frontal mass. Total removal of the mass lesion was performed without any neurological deficit. Pathological examination of the excised tumor was consistent with anaplastic ependymoma. We have discussed management strategy of this rare entity

Intracranial Germ Cell Tumors: Spectrum of Disease in an Indian Cohort and Management Strategies

Background: Germ cell tumors (GCTs) represent approximately 3% of primary pediatric brain tumors in the West, whereas in Asia, they constitute between 8% and 15% of pediatric brain tumors. Methods: We retrospectively studied all patients with intracranial GCT managed at our institute from January 1998 to December 2013. The clinical data and radiological data were analyzed. Results: Forty-eight patients with intracranial GCT including 36 males and 16 females formed the cohort. The proportion of GCT in our study was 0.29%. The mean age was 16.5 ± 2.5 years. Germinomas constituted 56.3% and nongerminomatous GCTs constituted 43.7% of all the tumors. The most common location was posterior third ventricle (58.3%) followed by suprasellar (22.9%). Histopathological diagnosis was obtained in almost all patients (96%). Surgical procedures included tumor decompression (71.7%), stereotactic biopsy (13%), and endoscopic third ventriculostomy and biopsy (15%). Patient's age, location of the tumor, and histology did not influence the survival. Women with GCTs had poorer survival when compared to men. Conclusions: The present study documented a lower hospital-based incidence of GCT in Indian cohort. A multidisciplinary approach including surgical strategy based on location, appropriate radiation planning, and chemotherapy is needed for effective treatment and improved outcomes

“Simple Methods to Derive Primary Malignant Glioma Cell Lines and Assay of Cellular Damage for Preclinical Studies”

<p>Primary malignant glioma cell lines are being used for initial screening of anticancer agents. We utilized a simple mechanical disaggregation method for deriving cell lines from tumor tissues; and a Coverslip Culture-Acridine Orange Staining method to study cellular damage. Cell lines could be grown for up to three passages within three weeks after surgery. Cell proliferation, total cellular damage, and MTT assay were studied as parameters of cytotoxic response. Frequencies of damaged cells varied in different cell lines; and increased after cytotoxic treatments under clinically relevant conditions. These methods could contribute to preclinical evaluation of treatment response before commencement of radio-chemotherapy.</p

Studies in electromagnetic wave interaction techniques./

The technique of interaction of guided electromagnetic waves in magneto plasmas is utilized to study the phenomena resulting from the cylotron resonance (f = fH= gyrofrequency of electrons) absorption of microwave energy by the electron gas. The enhancement in electronic energy caused by this absorption is experimentally evidenced by study of (1) gyro-interaction of microwaves of different frequencies, (2) emission of microwave noise power at frequencies fn greater than fH, (3) intensity of visible light excitation and, (4) rapid disintergration of the plasma. A correlation of these experimental results show that (1) the rate of heating of any specific region of the plasma changes drastically during different time intervals of the pulsed resonant heating microwave sitnal and (2) non-uniform heating occurs along the plasma axis. Implication of these results on wave propagation in a magnetoplasma will be discussed. Electron cyclotron resonance abosrption of microwave energy by the electron gas in decaying magneto plasmas of oxygen and nitrogen gases is investigated. (Author)."October 1963."The technique of interaction of guided electromagnetic waves in magneto plasmas is utilized to study the phenomena resulting from the cylotron resonance (f = fH= gyrofrequency of electrons) absorption of microwave energy by the electron gas. The enhancement in electronic energy caused by this absorption is experimentally evidenced by study of (1) gyro-interaction of microwaves of different frequencies, (2) emission of microwave noise power at frequencies fn greater than fH, (3) intensity of visible light excitation and, (4) rapid disintergration of the plasma. A correlation of these experimental results show that (1) the rate of heating of any specific region of the plasma changes drastically during different time intervals of the pulsed resonant heating microwave sitnal and (2) non-uniform heating occurs along the plasma axis. Implication of these results on wave propagation in a magnetoplasma will be discussed. Electron cyclotron resonance abosrption of microwave energy by the electron gas in decaying magneto plasmas of oxygen and nitrogen gases is investigated. (Author).Prepared for Air Force Cambridge Research Laboratories, Office of Aerospace Research, United States Air Force, L.G. Hanscom Field, Bedford, Massachusetts, under contract no.Mode of access: Internet